Astros vs. Angels Odds & Betting Predictions - June 22, 2025

Astros at Angels

1:38 am • FDSW

Houston Astros

75-60

1 - 9

Los Angeles Angels

62-72

pitcher		team	era	w-l
J.Soriano			3.85	9-9
B.Walter			3.35	1-3

MatchupOpenSpreadTotalMoneyline
Astros 75-60	-1.5	+1.5-194	o8.5-108	+108
Angels 62-72	u8.5	-1.5+168	u8.5-114	-130

Sunday 1:38 a.m.

June 22, 2025

Angel StadiumAnaheim

Under 4.5 (F5)-138

0.5u

Tailing @cawright95

B.Walter o4.5 Ks-110

Grabbing this too. Love what we’ve seen from Walter.

Under 4.5 (F5)-138

1.38u

Full writeup: https://www.actionnetwork.com/mlb/houston-astros-vs-los-angeles-angels-prediction-pick-odds-saturday-june-21-qs?utm_source=action_app&utm_medium=app&utm_campaign=article_share

B.Walter o4.5 Ks-118

HOU +110

0.5u

Bet to +100

LAA -125

0.8u

LAA -110

0.91u

Follow @PicksOffice on X to read the full writeup.

Under 8.5-117

1.17u

B.Walter u17.5 Outs+100

Under 4 (F5)-110

1.1u

B.Walter u4.5 Ks+115

LAA +101

1.01u

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Astros vs. Angels: How to Bet the F5
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Jun 21, 2025 UTC
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See more MLB Coverage

No props found

MLB Public Betting

Angels are 1-4 in their last 5 games.
Angels are 2-3 in their last 5 games against the spread
Angels are 33-32 in their road games against the spread
The totals have gone OVER in 2 of Angels' last 5 games
The totals have gone OVER in 38 of Angels' 69 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Angels	72-62	39-30	33-32	11-21	59-41
Astros	68-67	32-37	36-30	37-53	31-12

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Angels	73-57-4	38-28-3	35-29-1	17-14-1	55-42-3
Astros	61-68-6	29-39-1	32-29-5	41-47-2	18-21-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Angels	62-72	34-35	28-37	17-15	43-57
Astros	75-60	41-28	34-32	50-40	25-18

date	opponent	score	spread	over/under	moneyline
Jun 21st	HOU	L 2-3	+1.5 W	U 8	HOU +141
Jun 19th	@NYY	L 3-7	+1.5 L	U 10.5	NYY +230
Jun 18th	@NYY	W 3-2	+1.5 W	U 9.5	LAA +207
Jun 17th	@NYY	W 4-0	+1.5 W	U 9	LAA +198
Jun 16th	@NYY	W 1-0	+1.5 W	U 8	LAA +165

Anthony Rendon
3B
Rendon is out with hip
Out
Gustavo Campero
RF
Campero is out with ankle
Out

Jake Meyers
CF
Meyers is out with calf
Out
Luis Garcia
SP
Garcia is out with elbow
Out
Pedro Leon
RF
Leon is out with knee
Out
J.P. France
SP
France is out with shoulder
Out
Hayden Wesneski
RP
Wesneski is out with elbow
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
LB.Walter, P	99	6	6	7
RK.Ort, P	26	1	2	2
RN.Hernandez, P	23	1	1	0

HITTERS	H-AB	R	RBI
1J.Pena, SS	0-3	0	0
1C.Hummel, PH	0-0	0	0
1C.Hummel, LF	0-0	0	0
2I.Paredes, 3B	1-3	0	0
2M.Dubon, PH	0-1	0	0
2M.Dubon, SS	0-1	0	0
3J.Altuve, LF	0-0	1	0
3S.Whitcomb, PH	0-1	0	0
3S.Whitcomb, 2B	0-1	0	0
4Y.Diaz, C	0-4	0	0
4C.Salazar, C	0-0	0	0
5C.Smith, RF	0-4	0	0
6C.Walker, 1B	1-4	0	1
7V.Caratini, DH	0-4	0	0
8J.Meyers, CF	1-3	0	0
9L.Guillorme, 2B	0-3	0	0
9L.Guillorme, 3B	0-3	0	0

PITCHER	PC	IP	K	ER
RJ.Soriano, P	96	6.2	10	1
RH.Neris, P	4	0.1	1	0
RS.Bachman, P	22	2	2	0

HITTERS	H-AB	R	HR	RBI
1Z.Neto, SS	2-4	1	0	0
1K.Newman, SS	1-1	0	0	0
2N.Schanuel, 1B	2-3	1	0	1
2L.Wade, 1B	0-1	0	0	0
3M.Trout, DH	1-4	1	0	0
4T.Ward, LF	1-4	2	0	2
5L.O'Hoppe, C	2-4	2	2	4
6J.Adell, CF	1-3	1	0	0
7L.Rengifo, 3B	1-4	1	1	2
8G.Campero, RF	0-4	0	0	0
9C.Moore, 2B	0-4	0	0	0