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Red Wings vs. Sabres Odds & Betting Predictions - October 22, 2025

Red Wings at Sabres

11:30 pm • TNT

Detroit Red Wings

19-12-3
2
2 - 4

Buffalo Sabres

14-14-4
4

Red Wings at Sabres Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Red Wings
19-12-3
+1.5
+1.5-247
o6.5+105
-102
Sabres
14-14-4
u6.5
-1.5+195
u6.5-125
-122
location pinWednesday 11:30 p.m.
October 22, 2025
KeyBank CenterBuffalo
Red Wings vs. Sabres Expert Picks
VegasIsMyBitch
VegasIsMyBitch
Last 30d: 9-12-1 (-2.3u)
BUF +120 (Live)
0.6u
To Win in Regulation (No Overtime)
Bet Labs
Bet Labs
Last 30d: 26-14-0 (+9.8u)
Under 6.5-132
1u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 86-119-3 (-16.0u)
BUF -110
0.91u
The Degenerates
The Degenerates
Last 30d: 101-90-5 (+2.8u)
DET -110
1.1u
Picks Office
Picks Office
Last 30d: 191-144-1 (+27.5u)
DET +100
1u
X: PicksOffice
Scott Rickenbach
Scott Rickenbach
Last 30d: 91-99-0 (-18.8u)
BUF -110
0.91u
Nick Martin
Nick Martin
Last 30d: 72-98-1 (-5.6u)
T.Thompson Anytime Goal Scorer Yes+145
0.5u
https://www.dailyfaceoff.com/news/nhl-player-prop-bets-oct22
Allan Lem
Allan Lem
Last 30d: 176-127-1 (+10.8u)
B.Byram o0.5 Pts+185
0.26u
Tailing the ScoresAndOdds team
Lines at Lunch
Lines at Lunch
Last 30d: 5-4-0 (+1.1u)
BUF -104
1u

Red Wings vs. Sabres Previews & Analysis

  • Red Wings vs Sabres: A Moneyline Pick for Tonight article feature image

    Red Wings vs Sabres: A Moneyline Pick for Tonight

    Greg Liodice•
    Oct 22, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Red Wings vs. Sabres Public Betting Percentages

Away Logo

Red Wings

Public

Home Logo

Sabres

61%

Bets%

39%

Money%

NHL Public Betting Right Arrow

Betting Trends

  • Sabres are 3-2 in their last 5 games.
  • Sabres are 3-2 in their last 5 games against the spread
  • Sabres are 5-11 in their road games against the spread
  • The totals have gone OVER in 2 of Sabres' last 5 games
  • The totals have gone OVER in 6 of Sabres' 16 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Sabres		14-189-75-114-810-9
Red Wings		16-177-99-84-1111-5

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Sabres		15-176-109-76-68-11
Red Wings		18-1510-68-97-89-7

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Sabres		14-14N/AN/A6-68-11
Red Wings		18-12N/AN/A8-78-8

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 20th@MTLL 2-4+1.5 LU 6.5MTL +124
Oct 18thFLAW 3-0+1.5 WU 5.5BUF +130
Oct 15thOTTW 8-4+1.5 WO 6.5BUF -110
Oct 13thCOLL 1-3+1.5 LU 6.5COL +152
Oct 11th@BOSL 1-3+1.5 LU 5.5BOS -104

Sabres vs. Red Wings Injury Updates

Sabres Injuries

  • Jason Zucker
    LW

    Zucker is out with lower body

    Out

  • Michael Kesselring
    D

    Kesselring is out with lower body

    Out

  • Colten Ellis
    G

    Ellis is out with concussion

    Out

  • Justin Danforth
    RW

    Danforth is out with lower body

    Out

  • Jiri Kulich
    C

    Kulich is out with ear

    Out

Red Wings Injuries

  • Patrick Kane
    RW

    Kane is out with upper body

    Out

  • Mason Appleton
    C

    Appleton is out with lower body

    Out

See more NHL Injuries Right Arrow
Team Stats

2
Goals
4
4
Assists
8
5
Penalties
2
28
Shots
31
18
Hits
18
41
Faceoffs Won
32

Red Wings vs. Sabres Odds Comparison

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Red Wings at Sabres Team Totals

MatchupOverUnder
Red Wings
19-12-3
o2.5-165
u2.5+132
Sabres
14-14-4
o3.5+120
u3.5-158