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NFL Picks for Bills vs Browns, Vikings vs Giants & Falcons vs Cardinals (Sunday, Week 16)

NFL Picks for Bills vs Browns, Vikings vs Giants & Falcons vs Cardinals (Sunday, Week 16) article feature image
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Nathan Ray Seebeck-Imagn Images. Pictured: Atlanta Falcons running back Tyler Allgeier (25) is upended on a tackle

There are 12 games on Sunday's football slate, providing plenty of opportunities to find savvy NFL picks for Week 16.

Action PRO's premium tools are poring through advanced betting data and the latest real-time information to identify Sunday's smartest NFL picks, including:

  • Bills vs. Browns (1 p.m. ET, CBS)
  • Vikings vs. Giants (1 p.m. ET, FOX)
  • Falcons vs. Cardinals (4:05 p.m. ET, FOX)

Let's take a look at three NFL bets landing smart money, including a classic showdown between sharp and square bettors on Sunday afternoon.

3 Sharpest NFL Picks for Sunday, Week 16

*Odds as of Saturday afternoon

Bills vs. Browns Pick

Bills vs. Browns has the second-largest spread — Buffalo -10.5, to be exact — of the NFL Week 16 slate, but sharps are pivoting to a different bet for this matchup.