Virginia vs. Duke Odds & Betting Predictions - November 15, 2025

Virginia at Duke

8:30 pm • ESPN2

Virginia Cavaliers

10-3

34 - 17

Duke Blue Devils

8-5

MatchupOpenSpreadTotalMoneyline
Virginia 10-3	+5.5	+5.5-105	o60-114	+180
Duke 8-5	u61.5	-5.5-107	u60-109	-216

Saturday 8:30 p.m.

November 15, 2025

Brooks Field at Wallace Wade StadiumDurham

DUKE -110 (Live)

1.1u

DUKE -102 (Live)

0.25u

Boyd / FanDuel

UVA +155 (Live)

1.46u

DUKE -4.5-110

1.1u

DUKE -4-110

1.1u

DUKE -3.5-105

Over 59.5-105

@_Collin1 https://myaction.app/XOqm3YriiYb

UVA +5.5-110

Over 57.5-115

1.15u

Project 60; Mensah dominates Quarters and Cover 1 secondaries, both the primary coverage for UVA. Duke defense trending near dead last in multiple categories

Under 59.5-110

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See more NCAAF Coverage

No props found

NCAAF Public Betting

Duke are 4-1 in their last 5 games.
Duke are 3-2 in their last 5 games against the spread
Duke are 4-2 in their road games against the spread
The totals have gone OVER in 4 of Duke' last 5 games
The totals have gone OVER in 4 of Duke' 6 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Duke	7-6	2-4	4-2	5-4	2-2
Virginia	8-5	5-2	3-2	5-4	3-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Duke	9-4	4-2	5-1	6-3	3-1
Virginia	5-8	4-3	1-4	3-6	2-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Duke	8-5	N/A	N/A	6-3	2-2
Virginia	10-3	N/A	N/A	7-2	3-1

date	opponent	score	spread	over/under	moneyline
Nov 8th	@UCONN	L 34-37	-7.5 L	O 63.5	UCONN -310
Nov 1st	@CLEM	W 46-45	+4 W	O 54.5	DUKE +155
Oct 18th	GT	L 18-27	-3.5 L	U 61	GT -165
Oct 5th	@CAL	W 45-21	-3.5 W	O 55	DUKE -170
Sep 27th	@SYR	W 38-3	-4.5 W	U 55.5	DUKE -185