Missouri vs. Vanderbilt Odds & Betting Predictions - October 25, 2025

Missouri at Vanderbilt

7:30 pm • ESPN

Missouri Tigers

8-4

10 - 17

Vanderbilt Commodores

10-2

MatchupOpenSpreadTotalMoneyline
Missouri 8-4	+1.5	+3-105	o52.5-108	+130
Vanderbilt 10-2	u50.5	-3-115	u52.5-112	-155

Saturday 7:30 p.m.

October 25, 2025

FirstBank StadiumNashville

VAN -0.5 (Live)-120

MIZ +3-110

1.1u

MIZ +3-110

Matt 2 Frosty what up

MIZ +3-110

1.1u

VAN -2.5-110

🎶 Diego, Diego 🎶

MIZ +3-106

1.06u

Project Pk; Vandy lethal with Counter and Man block run concepts mixed with efficient inside zone. Missouri defends those concepts above national average and has limited explosives v Man and Counter

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See more NCAAF Coverage

No props found

NCAAF Public Betting

Vanderbilt are 4-1 in their last 5 games.
Vanderbilt are 5-0 in their last 5 games against the spread
Vanderbilt are 4-1 in their road games against the spread
The totals have gone OVER in 3 of Vanderbilt' last 5 games
The totals have gone OVER in 5 of Vanderbilt' 7 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Vanderbilt	10-2	6-1	4-1	5-1	4-1
Missouri	6-5-1	4-3-1	2-2	5-1	0-3-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Vanderbilt	8-4	5-2	3-2	5-1	3-2
Missouri	6-6	6-2	0-4	4-2	1-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Vanderbilt	10-2	N/A	N/A	6-0	3-2
Missouri	8-4	N/A	N/A	6-0	0-4

date	opponent	score	spread	over/under	moneyline
Oct 18th	LSU	W 31-24	-1.5 W	O 48.5	VAN -120
Oct 4th	@BAMA	L 14-30	+12.5 L	U 57.5	BAMA +385
Sep 27th	USU	W 55-35	-23.5 L	O 57.5	VAN -2100
Sep 20th	GAST	W 70-21	-27.5 W	O 52.5	VAN -4500
Sep 13th	@SC	W 31-7	+3 W	U 48.5	VAN +126