Twins vs. Guardians Odds & Betting Predictions - April 28, 2025
Twins at Guardians
10:10 pm • MNNTStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 3.06 | 12-5 | ||
![]() | 5.11 | 6-9 |
Twins at Guardians Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Twins 11-8 | +1.5 | +1.5-198 | o8-117 | +105 |
Guardians 11-9 | u8 | -1.5+167 | u8-105 | -125 |

Progressive FieldCleveland
Twins vs. Guardians Expert Picks
The Degenerate
Last 30d: 0-0-0 (+0.0u)
MIN +0.5 (F5)-140
0.54u
Picks Office
Last 30d: 202-200-7 (-11.2u)
CLE -120
1u
Twins can't win on the road – just 3-10 away this season, batting an ugly .188 with 2.92 R/9. Guardians strong at home – 8-4 record, offense jumps to 4.14 R/9. Gavin Williams (2-0, 2.38 ERA home) thrives at Progressive Field, Twins have lost 7 of last 8 here.
Bailey Ober’s road nightmares – 9.35 ERA, 1.96 WHIP in 8.2 IP away. Guardians bullpen edge – 2.89 ERA vs Twins’ 3.65 bullpen ERA season-long.
Cleveland better vs RHP – .238 AVG compared to Twins’ .232. Guardians’ offense has enough pop to expose Ober's road splits. Twins' brutal trend: 20 losses in last 26 road games. Home momentum, bullpen depth, starting pitching tilt to CLE.
Top Shelf Action 🥃
Last 30d: 280-256-8 (+7.1u)
E.Julien o1.5 Total Bases+185
1.11u
B.Naylor o0.5 Doubles+600
0.2u
Ryan Minion
Last 30d: 208-263-4 (-16.9u)
B.Buxton o1.5 Hits + Runs + RBIs-140
$1.00
Zense
Last 30d: 0-1-0 (-1.0u)
CLE -125
0.5u
#exclusive
Top Shelf Action 🥃
Last 30d: 280-256-8 (+7.1u)
K.Manzardo o0.5 Doubles+500
0.2u
Doug Ziefel
Last 30d: 273-368-21 (-23.0u)
CLE -125
0.63u
B.Ober u5.5 Ks-165
0.5u
Top Shelf Action 🥃
Last 30d: 280-256-8 (+7.1u)
C.Correa o1.5 RBI+650
0.2u
C.Correa o1.5 Hits+275
1.38u
Collin Whitchurch
Last 30d: 92-172-6 (+1.5u)
G.Williams o1.5 BB-175
0.5u
Greg DiNardo
Last 30d: 0-0-0 (+0.0u)
CLE -130
1.3u
Capper Central
Last 30d: 0-0-0 (+0.0u)
CLE PK-107
1.07u

Sean Zerillo
Last 30d: 143-142-7 (-10.2u)
CLE -110
0.55u
Bet to -121
Twins vs. Guardians Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Twins vs. Guardians Public Betting Percentages
Betting Trends
- Guardians are 2-3 in their last 5 games.
- Guardians are 2-3 in their last 5 games against the spread
- Guardians are 6-7 in their road games against the spread
- The totals have gone OVER in 3 of Guardians' last 5 games
- The totals have gone OVER in 2 of Guardians' 7 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Twins Injury Updates

Guardians Injuries

Twins Injuries
- Pablo LopezSP
Lopez is out with elbow
Out
- David FestaSP
Festa is out with shoulder
Out
- Travis AdamsSP
Adams is out with triceps
Out
Twins vs. Guardians Box Score
Twins Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 102 | 7.2 | 2 | 1 | |
![]() | 20 | 1.1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 1-5 | 1 | 1 | 1 |
![]() | 2-5 | 1 | 0 | 2 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 0 |
![]() | 1-1 | 1 | 0 | 0 |
![]() | 1-1 | 1 | 0 | 0 |
![]() | 1-5 | 1 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 2 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 2-4 | 2 | 1 | 3 |
![]() | 2-5 | 1 | 0 | 1 |
![]() | 3-5 | 1 | 0 | 1 |
![]() | 1-4 | 1 | 0 | 1 |
![]() | 1-4 | 1 | 0 | 1 |
Guardians Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 61 | 2 | 2 | 4 | |
![]() | 31 | 2 | 1 | 0 | |
![]() | 15 | 0.2 | 1 | 0 | |
![]() | 18 | 0.1 | 0 | 2 | |
![]() | 40 | 2 | 1 | 3 | |
![]() | 26 | 2 | 0 | 2 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 1-3 | 0 | 0 | 0 |
![]() | 1-1 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-3 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 1 |
![]() | 0-4 | 0 | 0 | 0 |
Twins vs. Guardians Odds Comparison
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Twins at Guardians Team Totals
MatchupOverUnder | ||
|---|---|---|
Twins 11-8 | N/A | N/A |
Guardians 11-9 | N/A | N/A |


































