Tigers vs. Guardians Odds & Betting Predictions - September 24, 2025

Tigers at Guardians

10:40 pm • FDSDET
1 - 5
Starting Pitchers
pitcherteameraw-l
Tanner Bibee logoT.BibeeCleveland Guardians logo4.2512-11
Jack Flaherty logoJ.FlahertyDetroit Tigers logo4.648-15

Tigers at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Tigers
87-75
-1.5
+1.5-186
o7.5-115
+119
Guardians
88-74
u8
-1.5+151
u7.5-105
-146
location pinWednesday 10:40 p.m.
September 24, 2025
Progressive FieldCleveland
Tigers vs. Guardians Expert Picks
Boomer Betz
Boomer Betz
Last 30d: 127-108-2 (+23.6u)
DET +118 (Live)
1u
The Degenerates
The Degenerates
Last 30d: 76-65-2 (+5.8u)
CLE -142
1u
Wags Wins
Wags Wins
Last 30d: 173-151-1 (+16.6u)
Under 8-119
1.26u
YBK Picks.com
Last 30d: 43-40-2 (-0.9u)
CLE -1+100
2u
Picks Office
Picks Office
Last 30d: 61-83-3 (-18.6u)
CLE -120
0.83u
Grant Neiffer
Grant Neiffer
Last 30d: 45-124-7 (+1.6u)
J.Ramirez o0.5 HR+450
0.25u
R.Greene o0.5 HR+425
0.25u
Bet Labs
Bet Labs
Last 30d: 23-14-0 (+7.6u)
CLE -153
0.93u
Lines at Lunch
Lines at Lunch
Last 30d: 98-97-3 (-5.7u)
Over 7.5-115
1.15u
Sean Zerillo
Sean Zerillo
Last 30d: 157-177-7 (-11.0u)
Over 7.5-108
0.54u
Bet to -115
Moneyline Hacks
Moneyline Hacks
Last 30d: 114-132-7 (+45.7u)
CLE -121
0.83u
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Tigers vs. Guardians Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Tigers vs. Guardians Public Betting Percentages

Away Logo

Tigers

Public

30%

Bets%

70%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
86-7639-4247-3433-3651-38
Tigers
73-8941-4032-4949-6424-23

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
69-87-637-41-332-46-334-34-134-50-5
Tigers
83-72-741-35-542-37-258-49-624-22-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
88-7445-3643-3844-2543-46
Tigers
87-7546-3541-4064-4923-24

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 23rdDETW 5-2+1.5 WO 6.5CLE +136
Sep 21st@MINL 2-6-1.5 LU 8.5MIN -143
Sep 20th@MINW 8-0-1.5 WU 8.5CLE -108
Sep 20th@MINW 6-0---
Sep 20th@MINW 6-2-1.5 WO 7.5CLE -113

Guardians vs. Tigers Injury Updates

Guardians Injuries

  • Edward Lively
    SP

    Lively is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

Tigers Injuries

  • Alexander Cobb
    SP

    Cobb is out with hip

    Out

  • Reese Olson
    SP

    Olson is out with shoulder

    Out

  • Tyler Madden
    SP

    Madden is out with shoulder

    Out

Tigers vs. Guardians Box Score
Tigers Player Stats
Projected
PITCHERPCIPKER
Jack Flaherty logoRJ.Flaherty, P834.163
Tyler Holton logoLT.Holton, P211.220
Rafael Montero logoRR.Montero, P14000
William Vest logoRW.Vest, P19110
Paul Sewald logoRP.Sewald, P8100
HITTERSH-ABRHRRBI
Parker Meadows logo1P.Meadows, CF0-2001
Jahmai Jones logo1J.Jones, PH0-1000
Jahmai Jones logo1J.Jones, RF0-1000
Gleyber Torres logo2G.Torres, 2B1-4000
Kerry Carpenter logo3K.Carpenter, DH0-4000
Spencer Torkelson logo4S.Torkelson, 1B1-4000
Riley Greene logo5R.Greene, LF1-3000
Wenceel Perez logo6W.Perez, RF0-3000
Wenceel Perez logo6W.Perez, CF0-3000
Zachary McKinstry logo7Z.McKinstry, 3B1-3000
Zachary McKinstry logo7Z.McKinstry, SS1-3000
Francis Dingler logo8D.Dingler, C1-4100
Trey Sweeney logo9T.Sweeney, SS1-2000
Andy Ibanez logo9A.Ibanez, PH0-1000
Andy Ibanez logo9A.Ibanez, 3B0-1000
Guardians Player Stats
Projected
PITCHERPCIPKER
Tanner Bibee logoRT.Bibee, P105651
Tim Herrin logoLT.Herrin, P140.210
Hunter Gaddis logoRH.Gaddis, P60.110
Jakob Junis logoRJ.Junis, P281.220
Cade Smith logoRC.Smith, P20.100
HITTERSH-ABRHRRBI
Steven Kwan logo1S.Kwan, LF1-4001
George Valera logo2G.Valera, DH1-4112
Jose Ramirez logo3J.Ramirez, 3B2-4002
Kyle Manzardo logo4K.Manzardo, 1B0-4000
Jhonkensy Noel logo4J.Noel, 1B0-0000
Noah Naylor logo5B.Naylor, C1-4000
Gabriel Arias logo6G.Arias, SS0-4000
Daniel Schneemann logo7D.Schneemann, CF0-3100
Daniel Schneemann logo7D.Schneemann, RF0-3100
CJ Kayfus logo8C.Kayfus, RF1-3000
Peter Halpin logo8P.Halpin, PR0-1100
Peter Halpin logo8P.Halpin, CF0-1100
Brayan Rocchio logo9B.Rocchio, 2B2-2200

Tigers vs. Guardians Odds Comparison

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Tigers at Guardians Team Totals

MatchupOverUnder
Tigers
87-75
o3.5-106
u3.5-120
Guardians
88-74
o3.5-148
u3.5+115