Guardians vs. Twins Odds & Betting Predictions - September 20, 2025

Guardians at Twins

6:10 pm • CLEG

Cleveland Guardians

6

6 - 0

Minnesota Twins

0

pitcher		team	era	w-l
J.Ryan			3.42	13-10
S.Cecconi			4.30	7-7

MatchupOpenSpreadTotalMoneyline
Guardians 1-2	N/A	N/A	N/A
Twins 0-0	N/A	N/A	N/A

location pin

Saturday 6:10 p.m.

September 20, 2025

Target FieldMinneapolis

MIN -115

1.5u

MIN -120

3u

Over 7.5-110

1u

Saturday's MLB Best Bets
Action Network Staff•
Sep 20, 2025 UTC

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MLB Public Betting

Twins are 2-3 in their last 5 games.
Twins are 3-2 in their last 5 games against the spread
Twins are 41-40 in their road games against the spread
The totals have gone OVER in 0 of Twins' last 5 games
The totals have gone OVER in 39 of Twins' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Twins	78-84	37-44	41-40	36-51	40-31
Guardians	86-76	39-42	47-34	33-36	51-38

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Twins	73-83-6	39-39-3	34-44-3	42-42-3	29-39-3
Guardians	69-87-6	37-41-3	32-46-3	34-34-1	34-50-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Twins	70-92	38-43	32-49	41-46	28-43
Guardians	88-74	45-36	43-38	44-25	43-46

date	opponent	score	spread	over/under	moneyline
Sep 20th	CLE	L 2-6	+1.5 L	O 7.5	CLE -108
Sep 17th	NYY	L 5-10	+1.5 L	O 9.5	NYY +134
Sep 16th	NYY	L 9-10	+1.5 W	O 9	NYY +144
Sep 15th	NYY	W 7-0	+1.5 W	U 9	MIN +163
Sep 14th	ARI	L 4-6	-1.5 L	O 9.5	ARI -125

Edward Lively
SP
Lively is out with elbow
Out
John Means
SP
Means is out with elbow
Out

Alan Roden
LF
Roden is out with thumb
Out

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PITCHER		PC	IP	K	ER
RS.Cecconi, P		98	7	8	0
LK.Allard, P		28	2	2	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	2-4	0	0	0
2A.Martinez, CF	0-3	0	0	0
3J.Ramirez, DH	1-4	1	1	1
4K.Manzardo, 1B	0-4	0	0	0
5B.Naylor, C	2-3	2	2	2
6G.Arias, SS	0-4	0	0	0
7G.Valera, RF	2-4	1	1	1
8D.Schneemann, 3B	1-4	1	1	1
9B.Rocchio, 2B	2-4	1	0	0

PITCHER		PC	IP	K	ER
RJ.Ryan, P		75	5	5	4
RT.Hatch, P		52	4	2	1

HITTERS	H-AB	R	HR	RBI
1B.Buxton, CF	0-4	0	0	0
2A.Martin, LF	2-4	0	0	0
3T.Larnach, DH	0-4	0	0	0
4L.Keaschall, 2B	1-3	0	0	0
5K.Clemens, 1B	0-3	0	0	0
6R.Lewis, 3B	0-3	0	0	0
7R.Fitzgerald, SS	0-1	0	0	0
8J.Pereda, C	0-3	0	0	0
9J.Outman, RF	0-3	0	0	0

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MatchupOverUnder
Guardians 1-2	N/A	N/A
Twins 0-0	N/A	N/A