Padres vs. Cardinals Odds & Betting Predictions - July 25, 2025
Padres at Cardinals
11:15 pm • FDSMWStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 4.84 | 8-11 | ||
![]() | 2.87 | 13-5 |
Padres at Cardinals Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Padres 1-2 | -1.5 | -1.5+134 | o8.5-112 | -130 |
Cardinals 0-0 | u8.5 | +1.5-158 | u8.5-106 | +110 |

Busch StadiumSt. Louis
Padres vs. Cardinals Expert Picks
Top Shelf Action 🥃
Last 30d: 185-167-1 (-4.8u)
SD -145 (F5)
0.73u
F5 Non Div Fav on Losing Streak (***)
Overall: 180-89-45,67% (ROI:14%)
Season:13-4-3,76% (ROI:25%)
Picks Office
Last 30d: 114-93-4 (+14.1u)
STL +120
1.2u
Player Prop Savant
Last 30d: 27-29-0 (-3.0u)
SD -136 (F5)
1.36u
Did not mean to play this for full unit - .5u spot
Top Shelf Action 🥃
Last 30d: 185-167-1 (-4.8u)
Under 8.5-105
1u
🔪
CeeJ Sports
Last 30d: 9-7-0 (+0.7u)
SD -130
1u
Nick Pivetta, that's it, place the bet. Pivetta is 10-2 with a 2.81 ERA this season and has been the Padres best pitcher. He now will face a Cardinals team that has been all over the place of late.
I would have loved to play a Pivetta ER prop here, but the books are heavily juicing his lines, so the moneyline is a nice 2nd option.
Mikolas will be on the mound for the Cardinals, and I think this Padres lineup can get to him. Mikolas holds a 5-7 record and a 5.20 ERA this season.
This Padres lineup is slowly waking up with guys like Jackson Merrill starting to heat back up, and Mikolas has a favorable pitch mix to provide some run support for Pivetta.
Grant Neiffer
Last 30d: 38-78-0 (+7.5u)
F.Tatis o0.5 HR+400
0.5u
Capper Central
Last 30d: 84-67-0 (+3.2u)
STL +1-118
1u
💰🦡 Jake
Last 30d: 118-133-6 (+2.2u)
SD -1.5+135
1u
Brian Bitler
Last 30d: 75-70-2 (+3.0u)
STL +120
3.6u
Kyle Murray
Last 30d: 67-65-2 (+5.4u)
SD -130 (F5)
1.3u
Padres vs. Cardinals Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Padres vs. Cardinals Public Betting Percentages
Betting Trends
- Cardinals are 1-4 in their last 5 games.
- Cardinals are 1-4 in their last 5 games against the spread
- Cardinals are 39-42 in their road games against the spread
- The totals have gone OVER in 3 of Cardinals' last 5 games
- The totals have gone OVER in 39 of Cardinals' 81 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Cardinals vs. Padres Injury Updates

Cardinals Injuries
- Masyn WinnSS
Masyn Winn (knee) has been scratched Friday.
Out

Padres Injuries
- Joe MusgroveSP
Musgrove is out for season with elbow
Out for Season
Padres vs. Cardinals Box Score
Padres Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 90 | 6.1 | 4 | 2 | |
![]() | 6 | 0.2 | 0 | 0 | |
![]() | 9 | 1 | 0 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 2-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-2 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
Cardinals Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 73 | 5 | 1 | 0 | |
![]() | 11 | 1 | 0 | 0 | |
![]() | 9 | 1 | 1 | 0 | |
![]() | 9 | 1 | 0 | 0 | |
![]() | 13 | 1 | 2 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 2-2 | 2 | 0 | 0 |
![]() | 0-3 | 1 | 0 | 0 |
![]() | 1-2 | 0 | 0 | 2 |
![]() | 0-3 | 0 | 0 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
Padres vs. Cardinals Odds Comparison
Could not load odds
Padres at Cardinals Team Totals
MatchupOverUnder | ||
|---|---|---|
Padres 1-2 | o4.5-105 | u4.5-122 |
Cardinals 0-0 | o3.5-135 | u3.5+105 |































