Cardinals vs. Diamondbacks Odds & Betting Predictions - July 20, 2025

Cardinals at Diamondbacks

8:10 pm • ARID

St. Louis Cardinals

22-15

3 - 5

Arizona Diamondbacks

17-19

pitcher		team	era	w-l
M.Kelly			4.23	3-3
M.Mikolas			4.84	8-11

MatchupOpenSpreadTotalMoneyline
Cardinals 22-15	+1.5	+1.5-175	o9+100	+121
Diamondbacks 17-19	u8.5	-1.5+143	u9-119	-145

Sunday 8:10 p.m.

July 20, 2025

Chase FieldPhoenix

M.Kelly u5.5 Ks-146

0.68u

Tailing @The_Oddsmaker

M.Kelly u5.5 Ks-146

0.5u

Kelly has cleared this in 3 of his last 5 starts, but two of those came against the Angels and Rockies…the top two easiest teams to K this season. He’s seen a sharp dip in whiff rate over his last two starts, which is a bit of a red flag, especially considering he’s been due for some regression according to my expected Ks model. His K% has been fairly matchup dependent all year, and today’s Cardinals lineup is one of the tougher ones he’s faced in terms of expected strikeout rate. His best K chances are the 2/4/8/9 hitters, but I have him getting pulled right around the 5–6 hitters the third time through, which limits his ceiling a bit. I’m projecting a fair price closer to -180.

ARI -140

$1.00

STL +136

M.Kelly u17.5 Outs+130

0.38u

ARI -145

Home Favorites Off a Blowout Overall: 141-50-0,74% (ROI:21%) Season:7-3-0,70% (ROI:13%)

STL +125

Cardinals vs. Diamondbacks: Expect Plenty of Runs
Action Network Staff•
Jul 20, 2025 UTC

See more MLB Coverage

No props found

MLB Public Betting

Diamondbacks are 1-4 in their last 5 games.
Diamondbacks are 2-3 in their last 5 games against the spread
Diamondbacks are 12-6 in their road games against the spread
The totals have gone OVER in 1 of Diamondbacks' last 5 games
The totals have gone OVER in 9 of Diamondbacks' 18 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Diamondbacks	23-13	11-7	12-6	7-5	15-8
Cardinals	24-13	12-8	12-5	1-1	23-12

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Diamondbacks	20-14-2	9-8-1	11-6-1	5-6-1	14-8-1
Cardinals	19-16-2	10-9-1	9-7-1	1-1	18-15-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Diamondbacks	17-19	10-8	7-11	7-5	9-14
Cardinals	22-15	10-10	12-5	1-1	21-14

date	opponent	score	spread	over/under	moneyline
Jul 19th	STL	W 10-1	+1.5 W	O 8.5	ARI +112
Jul 19th	STL	W 7-3	+1.5 W	O 8.5	ARI -110
Jul 13th	@LAA	W 5-1	+1.5 W	U 9	ARI +105
Jul 13th	@LAA	L 5-10	+1.5 L	O 9	LAA +106
Jul 12th	@LAA	L 5-6	-1.5 L	O 9	LAA -109

Corbin Burnes
SP
Burnes is out with elbow
Out
Blake Walston
SP
Walston is out with elbow
Out
Tyler Locklear
1B
Locklear is out with elbow
Out

Cristian Mena
SP
Mena is doubtful with shoulder
Doubtful

Lars Nootbaar
LF
Nootbaar is out with heel
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RM.Mikolas, P	68	4	3	5
LS.Matz, P	12	1	1	0
RR.O'Brien, P	17	1	2	0
LJ.Romero, P	15	1	2	0
RR.Helsley, P	15	1	1	0

HITTERS	H-AB	R	RBI
1B.Donovan, 2B	0-4	0	1
2I.Herrera, DH	1-4	0	1
3A.Burleson, LF	1-3	0	0
4W.Contreras, 1B	1-4	0	0
5N.Arenado, 3B	0-4	0	0
6M.Winn, SS	1-4	1	0
7Y.Pozo, C	0-3	1	0
8J.Walker, RF	2-3	0	1
9V.Scott, CF	1-3	1	0

PITCHER		PC	IP	K	ER
RM.Kelly, P		97	6	5	2
RA.DeSclafani, P		38	3	4	1

HITTERS	H-AB	R	HR	RBI
1C.Carroll, RF	2-4	1	0	0
2J.McCarthy, LF	0-3	0	0	0
2R.Grichuk, PH	0-1	0	0	0
2R.Grichuk, LF	0-1	0	0	0
3G.Perdomo, SS	1-4	1	0	1
4J.Naylor, 1B	1-3	1	0	0
5E.Suarez, 3B	2-4	2	2	4
6A.Del Castillo, DH	0-4	0	0	0
7B.Alexander, 2B	0-3	0	0	0
8A.Thomas, CF	1-3	0	0	0
9J.Herrera, C	0-2	0	0	0