Cubs vs. Reds Odds & Betting Predictions - September 20, 2025

Cubs at Reds

10:40 pm • MARQ

Chicago Cubs

3

3 - 6

Cincinnati Reds

6

pitcher		team	era	w-l
Z.Littell			3.58	8-8
J.Assad			3.65	4-1

MatchupOpenSpreadTotalMoneyline
Cubs 8-9	-1.5	-1.5+160	o9-109	-105
Reds 10-7	u9	+1.5-192	u9-110	-114

location pin

Saturday 10:40 p.m.

September 20, 2025

Great American Ball ParkCincinnati

Under 9-105

0.53u

D.Swanson o0.5 HR+498

0.25u

Under 9+105

2u

CHC -110

0.55u

Bet to -118

No props found

MLB Public Betting

Reds are 2-3 in their last 5 games.
Reds are 2-3 in their last 5 games against the spread
Reds are 5-2 in their road games against the spread
The totals have gone OVER in 4 of Reds' last 5 games
The totals have gone OVER in 6 of Reds' 10 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Reds	10-7	5-5	5-2	3-1	7-6
Cubs	6-11	3-6	3-5	3-8	3-3

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Reds	9-7-1	6-4	3-3-1	2-2	7-5-1
Cubs	10-7	5-4	5-3	6-5	4-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Reds	10-7	5-5	5-2	3-1	7-6
Cubs	8-9	4-5	4-4	5-6	3-3

date	opponent	score	spread	over/under	moneyline
Sep 19th	CHC	W 7-4	+1.5 W	O 8	CIN -110
Sep 18th	CHC	W 1-0	-1.5 L	U 8.5	CIN -145
Sep 17th	@STL	W 6-2	-1.5 W	U 8.5	CIN -120
Sep 16th	@STL	L 0-3	-1.5 L	U 8	STL -123
Sep 15th	@STL	W 11-6	-1.5 W	O 8.5	CIN -104

Nick Lodolo
SP
Lodolo is out with finger
Out
Hunter Greene
SP
Greene is out with elbow
Out

Tyler Austin
1B
Austin is out with knee
Out
Justin Steele
SP
Steele is out with elbow
Out
Jordan Wicks
SP
Wicks is out with arm
Out

See more MLB Injuries

PITCHER		PC	IP	K	ER
RJ.Assad, P		74	4	2	2
LD.Pomeranz, P		13	1	2	1
RA.Civale, P		29	2	3	1
RA.Kittredge, P		19	1	2	2

HITTERS	H-AB	R	HR	RBI
1M.Busch, 1B	1-4	1	1	1
2N.Hoerner, 2B	2-4	0	0	0
3I.Happ, LF	0-4	0	0	0
4M.Ballesteros, DH	0-3	0	0	0
5D.Swanson, SS	0-4	0	0	0
6P.Crow-Armstrong, CF	0-4	0	0	0
7M.Shaw, 3B	1-4	0	0	0
8W.Castro, RF	1-3	1	0	0
8S.Suzuki, PH	0-1	0	0	0
9R.McGuire, C	2-3	1	1	2
9K.Alcantara, PR	0-0	0	0	0
9C.Kelly, C	0-0	0	0	0

PITCHER		PC	IP	K	ER
RZ.Littell, P		73	5	4	2
RG.Ashcraft, P		6	1	0	0
RC.Burns, P		36	1.1	1	1
RT.Santillan, P		8	0.2	1	0
RE.Pagan, P		13	1	1	0

HITTERS	H-AB	R	HR	RBI
1T.Friedl, CF	2-4	2	1	1
2S.Steer, 1B	1-4	1	1	2
2S.Steer, LF	1-4	1	1	2
3G.Lux, DH	0-2	0	0	0
3M.Andujar, PH	1-2	0	0	0
3M.Andujar, DH	1-2	0	0	0
4A.Hays, LF	0-3	0	0	0
4S.Stewart, 1B	0-1	0	0	0
5W.Benson, RF	1-2	0	0	1
5N.Marte, PH	1-2	1	0	0
5N.Marte, RF	1-2	1	0	0
6E.De La Cruz, SS	1-3	0	0	0
7T.Stephenson, C	1-3	1	1	2
8K.Hayes, 3B	0-4	0	0	0
9M.McLain, 2B	1-4	1	0	0

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See more MLB Odds

MatchupOverUnder
Cubs 8-9	N/A	N/A
Reds 10-7	N/A	N/A