Cubs vs. Reds Odds & Betting Predictions - September 18, 2025

Cubs at Reds

11:15 pm • FOX

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Chicago Cubs

@

Cincinnati Reds

pitcher		team	era	w-l
H.Greene			3.01	6-4
C.Rea			4.23	10-6

MatchupOpenSpreadTotalMoneyline
Cubs 87-64	N/A	N/A	N/A
Reds 75-76	N/A	N/A	N/A

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Thursday 11:15 p.m.

September 18, 2025

Great American Ball ParkCincinnati

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81°Fahrenheit

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0%Rain

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2Wind

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MLB Public Betting

Reds are 1-4 in their last 5 games.
Reds are 1-4 in their last 5 games against the spread
Reds are 39-38 in their road games against the spread
The totals have gone OVER in 3 of Reds' last 5 games
The totals have gone OVER in 25 of Reds' 72 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Reds	77-72	38-34	39-38	27-38	50-33
Cubs	71-80	35-40	36-40	50-58	20-22

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Reds	56-84-9	25-41-6	31-43-3	20-42-3	35-42-6
Cubs	67-75-9	35-35-5	32-40-4	46-55-7	21-19-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Reds	75-76	39-33	35-42	34-31	40-43
Cubs	87-64	46-29	41-35	68-40	18-24

date	opponent	score	spread	over/under	moneyline
Sep 17th	@STL	W 6-2	-1.5 W	U 8.5	CIN -120
Sep 16th	@STL	L 0-3	-1.5 L	U 8	STL -123
Sep 15th	@STL	W 11-6	-1.5 W	O 8.5	CIN -104
Sep 14th	@ATH	L 4-7	-1.5 L	O 9.5	ATH -112
Sep 14th	@ATH	L 5-11	-1.5 L	O 9	ATH -121

Michael Soroka
SP
Soroka is out with shoulder
Out
Justin Steele
SP
Steele is out for season with elbow
Out for Season

Noelvi Marte
3B
Marte is day-to-day with side
Day-to-Day
Reiver Sanmartin
RP
Sanmartin is out with elbow
Out
Brandon Williamson
SP
Williamson is out for season with elbow
Out for Season
Graham Ashcraft
RP
Ashcraft is out with groin
Out
Chase Burns
SP
Burns is out with hip
Out
Julian Aguiar
SP
Aguiar is out for season with elbow
Out for Season
Rhett Lowder
SP
Lowder is out with elbow
Out
Carson Spiers
RP
Spiers is out with shoulder
Out

See more MLB Injuries

PITCHER		W-L	ERA	WHIP	K/9
RC.Rea, P		10-6	4.23	1.309	6.69

HITTERS	AVG	OBP	SLG	HR
1M.Busch, 1B	.259	.337	.498	29
2N.Hoerner, 2B	.301	.351	.401	6
3I.Happ, LF	.241	.345	.419	22
4M.Ballesteros, DH	.306	.390	.472	1
5S.Suzuki, RF	.244	.324	.461	27
6C.Kelly, C	.257	.341	.449	17
7P.Crow-Armstrong, CF	.248	.290	.485	29
8D.Swanson, SS	.250	.304	.422	22
9M.Shaw, 3B	.224	.291	.378	11

PITCHER		W-L	ERA	WHIP	K/9
RH.Greene, P		6-4	3.01	0.993	11.27

HITTERS	AVG	OBP	SLG	HR
1T.Friedl, CF	.259	.364	.370	12
2G.Lux, DH	.263	.349	.369	5
3N.Marte, RF	.272	.313	.473	13
4S.Stewart, 1B	.275	.293	.575	4
5W.Benson, LF	.233	.281	.461	12
6T.Stephenson, C	.225	.310	.404	11
7E.De La Cruz, SS	.264	.334	.435	19
8K.Hayes, 3B	.254	.327	.381	3
9M.McLain, 2B	.225	.306	.349	14

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MatchupOverUnder
Cubs 87-64	N/A	N/A
Reds 75-76	N/A	N/A