Cubs vs. Reds Odds & Betting Predictions - September 19, 2025

Cubs at Reds

10:40 pm • MARQ

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Chicago Cubs

@

Cincinnati Reds

pitcher		team	era	w-l
N.Lodolo			3.30	8-8
S.Imanaga			3.29	9-7

MatchupOpenSpreadTotalMoneyline
Cubs 88-65	-1.5	-1.5+135	o8.5-105	-125
Reds 77-76	u9	+1.5-165	u8.5-115	+105

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Friday 10:40 p.m.

September 19, 2025

Great American Ball ParkCincinnati

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82°Fahrenheit

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0%Rain

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2Wind

CHC -120

0.6u

No props found

MLB Public Betting

Reds are 3-2 in their last 5 games.
Reds are 2-3 in their last 5 games against the spread
Reds are 40-38 in their road games against the spread
The totals have gone OVER in 2 of Reds' last 5 games
The totals have gone OVER in 25 of Reds' 73 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Reds	78-73	38-35	40-38	28-39	50-33
Cubs	73-80	35-40	38-40	51-58	21-22

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Reds	56-86-9	25-42-6	31-44-3	20-44-3	35-42-6
Cubs	68-76-9	35-35-5	33-41-4	47-55-7	21-20-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Reds	77-76	40-33	36-42	36-31	40-43
Cubs	88-65	46-29	42-36	69-40	18-25

date	opponent	score	spread	over/under	moneyline
Sep 18th	CHC	W 1-0	-1.5 L	U 8.5	CIN -145
Sep 17th	@STL	W 6-2	-1.5 W	U 8.5	CIN -120
Sep 16th	@STL	L 0-3	-1.5 L	U 8	STL -123
Sep 15th	@STL	W 11-6	-1.5 W	O 8.5	CIN -104
Sep 14th	@ATH	L 4-7	-1.5 L	O 9.5	ATH -112

Michael Soroka
SP
Soroka is out with shoulder
Out
Justin Steele
SP
Steele is out for season with elbow
Out for Season

Noelvi Marte
3B
Marte is day-to-day with side
Day-to-Day
Reiver Sanmartin
RP
Sanmartin is out with elbow
Out
Brandon Williamson
SP
Williamson is out for season with elbow
Out for Season
Graham Ashcraft
RP
Ashcraft is out with groin
Out
Chase Burns
SP
Burns is out with hip
Out
Julian Aguiar
SP
Aguiar is out for season with elbow
Out for Season
Rhett Lowder
SP
Lowder is out with elbow
Out
Carson Spiers
RP
Spiers is out with shoulder
Out

See more MLB Injuries

PITCHER		W-L	ERA	WHIP	K/9
LS.Imanaga, P		9-7	3.29	0.948	7.39

HITTERS	AVG	OBP	SLG	HR
1N.Hoerner, 2B	.301	.350	.399	6
2I.Happ, LF	.241	.344	.422	23
3S.Suzuki, DH	.244	.324	.459	27
4C.Kelly, C	.254	.338	.445	17
5J.Turner, 1B	.223	.292	.325	3
6D.Swanson, SS	.249	.303	.419	22
7P.Crow-Armstrong, CF	.246	.287	.481	29
8W.Castro, RF	.245	.335	.407	10
9M.Shaw, 3B	.220	.290	.372	11

PITCHER		W-L	ERA	WHIP	K/9
LN.Lodolo, P		8-8	3.30	1.044	8.52

HITTERS	AVG	OBP	SLG	HR
1T.Friedl, CF	.257	.362	.368	12
2N.Marte, RF	.274	.315	.472	13
3M.Andujar, DH	.298	.329	.436	6
4A.Hays, LF	.269	.319	.460	15
5S.Stewart, 3B	.267	.313	.556	4
6S.Steer, 1B	.240	.309	.403	18
7E.De La Cruz, SS	.261	.332	.430	19
8J.Trevino, C	.249	.285	.368	4
9M.McLain, 2B	.222	.304	.345	14

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MatchupOverUnder
Cubs 88-65	N/A	N/A
Reds 77-76	N/A	N/A