Cubs vs. Pirates Odds & Betting Predictions - September 17, 2025

Cubs at Pirates

4:35 pm • MLB Network

Chicago Cubs

87-64

8 - 4

Pittsburgh Pirates

65-87

pitcher		team	era	w-l
J.Oviedo			2.81	2-0
M.Boyd			3.05	13-8

MatchupOpenSpreadTotalMoneyline
Cubs 87-64	-1.5	-1.5+117	o7.5-116	-145
Pirates 65-87	u8	+1.5-141	u7.5-105	+121

Wednesday 4:35 p.m.

September 17, 2025

PNC ParkPittsburgh

Under 8-118

1.18u

PIT +140

Under 8-118

1.18u

Under 8.5-148

0.5u

PIT +123

Under 8-120

1.2u

Under 8-120

1.2u

CHC -141

PIT +140

0.5u

Bet to +130

CHC -154

1.3u

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No props found

MLB Public Betting

Pirates are 1-4 in their last 5 games.
Pirates are 1-4 in their last 5 games against the spread
Pirates are 37-38 in their road games against the spread
The totals have gone OVER in 1 of Pirates' last 5 games
The totals have gone OVER in 31 of Pirates' 77 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Pirates	82-70	45-32	37-38	18-26	62-43
Cubs	71-80	35-40	36-40	50-58	20-22

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Pirates	58-86-8	31-41-5	27-45-3	16-26-2	40-59-6
Cubs	67-75-9	35-35-5	32-40-4	46-55-7	21-19-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Pirates	65-87	42-35	23-52	21-23	43-62
Cubs	87-64	46-29	41-35	68-40	18-24

date	opponent	score	spread	over/under	moneyline
Sep 16th	CHC	L 1-4	-1.5 L	U 6.5	CHC -131
Sep 15th	CHC	L 0-4	+1.5 L	U 8	CHC +102
Sep 14th	@WSH	L 3-4	-1.5 L	U 8.5	WSH -120
Sep 13th	@WSH	W 5-1	-1.5 W	U 9	PIT -115
Sep 12th	@WSH	L 5-6	-1.5 L	O 8.5	WSH -110

Johan Oviedo
SP
Oviedo is questionable with elbow
Questionable

Endy Rodriguez
1B
Rodriguez is out with elbow
Out
Jared Jones
SP
Jones is out with elbow
Out

Michael Soroka
SP
Soroka is out with shoulder
Out
Justin Steele
SP
Steele is out for season with elbow
Out for Season

See more MLB Injuries

PITCHER	PC	IP	K	ER
LM.Boyd, P	83	3	5	4
RP.Hodge, P	19	1	2	0
RA.Civale, P	55	3	3	0
LD.Pomeranz, P	24	1	1	0
LT.Rogers, P	14	1	0	0

HITTERS	H-AB	R	HR	RBI
1M.Busch, 1B	0-2	1	0	1
2N.Hoerner, 2B	2-4	3	0	0
3I.Happ, LF	2-4	1	1	3
4M.Ballesteros, DH	1-3	1	1	1
4J.Turner, PH	2-2	0	0	2
4J.Turner, DH	2-2	0	0	2
5S.Suzuki, RF	0-3	0	0	0
5K.Alcantara, RF	0-1	0	0	0
6P.Crow-Armstrong, CF	1-5	0	0	0
7D.Swanson, SS	1-4	1	0	0
8R.McGuire, C	1-5	0	0	0
9M.Shaw, 3B	0-3	1	0	0

PITCHER	PC	IP	K	ER
RJ.Oviedo, P	99	5	3	4
RY.Ramirez, P	18	0.2	0	0
LE.Sisk, P	9	0.1	0	0
RD.Moreta, P	32	1.1	1	1
RK.Nicolas, P	11	0.2	1	0
RD.Santana, P	12	1	1	0

HITTERS	H-AB	R	HR	RBI
1J.Triolo, SS	2-5	0	0	0
2N.Gonzales, 2B	2-4	0	0	0
3T.Pham, LF	0-4	1	0	0
4A.McCutchen, DH	1-4	1	0	1
5J.Bart, C	1-4	1	1	3
6A.Canario, CF	1-3	0	0	0
6O.Cruz, PH	0-2	0	0	0
6O.Cruz, CF	0-2	0	0	0
7N.Yorke, RF	1-4	0	0	0
7N.Yorke, 3B	1-4	0	0	0
8R.Flores, 1B	1-3	0	0	0
9C.Devanney, 3B	1-2	1	0	0
9J.Suwinski, PH	0-2	0	0	0
9J.Suwinski, RF	0-2	0	0	0