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Chiefs vs. Cardinals Odds & Betting Predictions - August 10, 2025

Chiefs at Cardinals

12:00 am • NFL+

Kansas City Chiefs

5-3
17
17 - 20

Arizona Cardinals

2-5
20

Chiefs at Cardinals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Chiefs
5-3
-1.5
-2.5-115
o40.5-118
-145
Cardinals
2-5
u35.5
+2.5-105
u40.5-110
+124
location pinSunday 12:00 a.m.
August 10, 2025
State Farm StadiumGlendale
Chiefs vs. Cardinals Expert Picks
Brian Bitler
Brian Bitler
Last 30d: 75-76-2 (-12.8u)
ARI +3-112
2.68u

Chiefs vs. Cardinals Props

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Chiefs vs. Cardinals Public Betting Percentages

Away Logo

Chiefs

Public

Home Logo

Cardinals

68%

Bets%

32%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Cardinals are 1-4 in their last 5 games.
  • Cardinals are 3-2 in their last 5 games against the spread
  • Cardinals are 3-0 in their road games against the spread
  • The totals have gone OVER in 2 of Cardinals' last 5 games
  • The totals have gone OVER in 3 of Cardinals' 4 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cardinals		4-31-33-01-23-1
Chiefs		5-34-11-14-21-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cardinals		4-33-11-22-12-2
Chiefs		3-51-41-12-41-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cardinals		2-5N/AN/A2-10-4
Chiefs		5-3N/AN/A4-21-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jan 5thSFW 47-24-5.5 WO 43.5ARI -240
Dec 29th@LAL 9-13+6.5 WU 48LA +245
Dec 22nd@CARL 30-36-5.5 LO 47CAR -245
Dec 15thNEW 30-17-6 WO 46.5ARI -264
Dec 8thSEAL 18-30-3 LO 45.5SEA -177

Chiefs vs. Cardinals Injury Updates

Chiefs Injuries

  • Isiah Pacheco
    RB

    Pacheco is doubtful with knee

    Doubtful

  • Esa Pole
    T

    Pole is out with ankle

    Out

Cardinals Injuries

  • James Conner
    RB

    Conner is out with foot

    Out

  • Kyler Murray
    QB

    Murray is questionable with foot

    Questionable

  • Owen Pappoe
    LB

    Pappoe is questionable with quad

    Questionable

  • Emari Demercado
    RB

    Demercado is out with ankle

    Out

  • Trey Benson
    RB

    Benson is out with knee

    Out

  • Tip Reiman
    TE

    Reiman is out with ankle

    Out

See more NFL Injuries Right Arrow
Team Stats

Total

249
Total Yards
355
62
Total Plays
61
4
Yards Per Play
5.8

Passing

164
YDS
224
21/40
Comps/Atts
17/25
3.829
YPA
8.269
1/2
TDs/INTs
2/2
1/7
Sacks/Yards
1/9

Rushing

92
Rush Yards
140
21
Attempts
35
4.381
YPC
4
1
TDs
0

Turnovers

0
Fumbles Lost
1
2
Interceptions
2

Efficiency

2/2 100%
Redzone
1/3 33.33%
5/13 0%
3rd Down
4/9 0%
1/1 0%
4th Down
0/0 0%

First Downs

17
Total
24
9
Pass
13
6
Rush
7
2
Penalty
4

Misc

11/113
Penalties/Yards
5/47
29:36
Possession
30:24

Chiefs vs. Cardinals Odds Comparison

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Chiefs at Cardinals Team Totals

MatchupOverUnder
Chiefs
5-3
o21.5-115
u21.5-110
Cardinals
2-5
o19.5-115
u19.5-110