The Arizona Cardinals (0-0) and New Orleans Saints (0-0) will face off in NFL Week 1. Kickoff is set for in 1:00 p.m. EDT from Caesars Superdome in New Orleans, La. The game will broadcast live on CBS.
The Cardinals are favored by -6 on the spread with the game total set at 44.5. The Cardinals are -278 moneyline favorites to win outright and the Saints are +220 underdogs.
Let's get into my Cardinals vs Saints predictions and parlay picks for Sunday afternoon.
Cardinals vs Saints Prediction, Parlay Picks
- Cardinals Moneyline (-285)
- Chris Olave 60+ Receiving Yards (+123)
Parlay Odds: +195 (Fanatics)
Arizona Cardinals vs New Orleans Saints Odds
| Cardinals Odds | ||
|---|---|---|
| Spread | Over/Under | Moneyline |
-6 -108 | 44.5 -108o / -112u | -278 |
| Saints Odds | ||
|---|---|---|
| Spread | Over/Under | Moneyline |
+6 -112 | 44.5 -108o / -112u | +220 |
Cardinals vs Saints Preview, Parlay Picks
Cardinals Moneyline
New Orleans will be one of the worst teams in football this season, mainly due to their below-average offense. Meanwhile, I am optimistic about this Cardinals; I think Kyler Murray will have the Cardinals' offense ready to go, and I expect Arizona to control the pace of this game.
It's hard to see a path to victory here for the Saints, who are starting Spencer Rattler at quarterback
New Orleans will struggle to keep pace this afternoon.
Chris Olave 60+ Receiving Yards
Olave had a quiet 2024 season due to injuries. The former Ohio State standout was limited to just eight games with 32 receptions, 400 yards and a touchdown. It was the first time he didn't surpass 1,000 receiving yards in his NFL career.
But Olave appears to be fully healthy heading into the season, which is a scary sight for the rest of the league. Beyond Olave, there' not much else the Saints have going on besides Alvin Kamara.
The Cardinals enter this game as 5.5-point favorites on the spread, so the potential trailing game script bodes well for Olave, who is one of the few quality pieces on the Saints offense.
Cardinals vs Saints Same-Game Parlay
- Cardinals Moneyline
- Chris Olave 60+ Receiving Yards
Parlay Odds: +195 (Fanatics)
