Missouri vs. Oklahoma Odds & Betting Predictions - November 22, 2025

Missouri at Oklahoma

5:00 pm • ABC

Missouri Tigers

8-4

6 - 17

Oklahoma Sooners

10-2

MatchupOpenSpreadTotalMoneyline
Missouri 8-4	+9	+4.5-112	o42.5-115	+172
Oklahoma 10-2	u54.5	-4.5-108	u43-110	-210

Saturday 5:00 p.m.

November 22, 2025

Gaylord Family Oklahoma Memorial StadiumNorman

X.Robinson u54.5 Rush Yds-115

0.65u

MIZ +5.5+100

Under 43.5-110

0.91u

Degen’s sleepytime tea

MIZ +5.5-105

OU -5.5-110

0.05u

Can try for small middle with low total. 6.5/7 probably right here especially with Pribula uncertainty

MIZ +6.5-105

Link in Bio for early access

MIZ +5.5-105

1.05u

OU -6.5-108

0.93u

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MIZ u17.5-125

0.53u

MIZ +7.5-105

Agree Board @Stuckey2 @_Collin1 https://myaction.app/froqdThRtYb

MIZ +8-110

0.3u

From podcast. Out in a bit!

MIZ +7.5-112

1.12u

As discussed on BBOC

Over 41-120

1.2u

Buying half point to key 41; OU outside top 50 in PFF tackling and broken tackles allowed. Missouri 95th defensive finishing drives

MIZ +7.5-110

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MIZ +9.5-110

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See more NCAAF Coverage

No props found

NCAAF Public Betting

Oklahoma are 4-1 in their last 5 games.
Oklahoma are 4-1 in their last 5 games against the spread
Oklahoma are 4-0 in their road games against the spread
The totals have gone OVER in 1 of Oklahoma' last 5 games
The totals have gone OVER in 1 of Oklahoma' 7 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Oklahoma	7-5	3-4	4-0	5-2	2-1
Missouri	6-5-1	4-3-1	2-2	5-1	0-3-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Oklahoma	2-10	1-6	1-3	1-6	1-2
Missouri	6-6	6-2	0-4	4-2	1-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Oklahoma	10-2	N/A	N/A	6-1	2-1
Missouri	8-4	N/A	N/A	6-0	0-4

date	opponent	score	spread	over/under	moneyline
Nov 15th	@BAMA	W 23-21	+6.5 W	U 46.5	OU +195
Nov 1st	@TENN	W 33-27	+3 W	O 55.5	OU +130
Oct 25th	MISS	L 26-34	-4.5 L	O 52.5	MISS -200
Oct 18th	@SC	W 26-7	-4.5 W	U 42.5	OU -192
Oct 11th	@TEX	L 6-23	+2.5 L	U 44.5	TEX +124