Duke vs. Louisville Odds & Betting Predictions - January 7, 2026

Duke at Louisville

12:00 am • ESPN
84 - 73

Duke at Louisville Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Duke
14-1
+2.5
-1.5-105
o161.5-110
-112
Louisville
11-4
u160.5
+1.5-115
u161.5-112
-108
location pinWednesday 12:00 a.m.
January 07, 2026
KFC Yum! CenterLouisville
Duke vs. Louisville Expert Picks
Jeremiah Rose
Jeremiah Rose
Last 30d: 32-27-1 (+2.6u)
DUKE +5 (Live)-112
0.18u
Boyd / FanDuel
FTN Fantasy
FTN Fantasy
Last 30d: 143-116-1 (+13.0u)
LOU +1.5-116
1u
Wags Wins
Wags Wins
Last 30d: 224-228-4 (+5.2u)
Under 162.5-115
1.09u
Nick Giffen
Nick Giffen
Last 30d: 29-75-1 (-13.6u)
Over 161.5-110
0.28u
Have this at 165.5 Tanner's projections have 165.1 Over it is.
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 121-97-1 (+33.9u)
LOU PK-110
0.5u
#RLM
Mjaybrod
Mjaybrod
Last 30d: 77-70-0 (+2.0u)
LOU +114
1u
Boosted
The Pick Don
The Pick Don
Last 30d: 11-9-0 (+1.0u)
LOU -110
1.1u
Stuck 🚨
Stuck 🚨
Last 30d: 62-51-7 (+4.5u)
LOU +1-110
0.3u
Anders
Anders
Last 30d: 19-12-0 (+5.5u)
LOU +1.5-110
1.1u
Analysis in Twitter Vid
Boomer Betz
Boomer Betz
Last 30d: 112-126-0 (-24.2u)
DUKE +2.5-120
$100.00

Duke vs. Louisville Previews & Analysis

  • Duke vs Louisville: Over/Under Pick for 3-Happy Matchup article feature image

    Duke vs Louisville: Over/Under Pick for 3-Happy Matchup

    Jordan Mann
    Jan 6, 2026 UTC
  • Our CBB Best Bets for Tuesday article feature image

    Our CBB Best Bets for Tuesday

    Action Network Staff
    Jan 6, 2026 UTC
  • System on 10-2 Run Picks Duke vs. Louisville article feature image

    System on 10-2 Run Picks Duke vs. Louisville

    Action AI
    Jan 6, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Duke vs. Louisville Public Betting Percentages

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Duke

Public

68%

Bets%

32%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Louisville
9-66-33-36-20-2
Duke
8-75-63-15-5N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Louisville
6-94-52-44-40-2
Duke
5-103-82-23-7N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Louisville
11-4N/AN/A6-20-2
Duke
14-1N/AN/A9-1N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jan 3rd@STANL 76-80-8 LU 157.5STAN -421
Dec 31st@CALW 90-70-8.5 WU 161.5LOU -346
Dec 20thMONTW 94-54-30.5 WU 166.5LOU -20000
Dec 17th@TENNL 62-83+4.5 LU 156.5TENN +146
Dec 13thMEMW 99-73-16.5 WO 162.5LOU -1800
Team Stats
29-57 (51%)
Field Goals
26-65 (40%)
19-28 (68%)
Free Throws
9-12 (75%)
7-23 (30%)
3P
12-38 (32%)
36
Rebounds
37
9
Assists
13
12
Turnovers
14
11
Steals
7
2
Blocks
1
17
Fouls
20

Duke vs. Louisville Odds Comparison

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Duke at Louisville Team Totals

MatchupOverUnder
Duke
14-1
o80.5-120
u80.5-110
Louisville
11-4
o80.5-120
u80.5-110