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Trail Blazers vs. Spurs Odds & Betting Predictions - April 22, 2026

Trail Blazers at Spurs

12:00 am • NBC/Peacock

Portland Trail Blazers

1-4
106
106 - 103

San Antonio Spurs

4-1
103

Trail Blazers at Spurs Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Trail Blazers
1-4
+12.5
+11.5-115
o221.5-112
+450
Spurs
4-1
u221.5
-11.5-105
u221.5-105
-650
location pinWednesday 12:00 a.m.
April 22, 2026
Frost Bank CenterSan Antonio
Trail Blazers vs. Spurs Expert Picks
Joe Dellera
Joe Dellera
Last 30d: 78-104-2 (+35.4u)
D.Avdija o21.5 Pts (Live)-115
1u
Brandon Kravitz
Brandon Kravitz
Last 30d: 60-98-3 (-34.4u)
POR +7.5 (Live)-105
1u
Wemby’s face hit the floor, might not be coming back.
The Propfessor
The Propfessor
Last 30d: 45-58-0 (+6.0u)
S.Castle o16.5 Pts-125
0.4u
S.Castle To Make 2+ Threes Yes+138
0.69u
Alex Hinton
Alex Hinton
Last 30d: 60-107-1 (-18.6u)
L.Kornet o8.5 Pts+Rebs+104
1.04u
Kyle Murray
Kyle Murray
Last 30d: 40-59-3 (-0.3u)
J.Holiday o20.5 Pts+Ast-128
1u
V.Wembanyama o38.5 Pts+Rebs-122
1.22u
The Degenerates
The Degenerates
Last 30d: 96-102-9 (-9.4u)
D.Avdija o23.5 Pts-114
1.14u
V.Wembanyama o28.5 Pts-106
1.06u
Mjaybrod
Mjaybrod
Last 30d: 29-31-0 (-1.6u)
POR o103.5-115
1.74u
NBA POD
Collin Whitchurch
Collin Whitchurch
Last 30d: 38-71-3 (-5.7u)
SAS -3.5 (1Q)-112
0.28u
Joe Dellera
Joe Dellera
Last 30d: 78-104-2 (+35.4u)
SAS -3.5 (1Q)-110
1u
Wags Wins
Wags Wins
Last 30d: 251-284-6 (-24.3u)
SAS o116.5+100
0.75u
Alex Hinton
Alex Hinton
Last 30d: 60-107-1 (-18.6u)
S.Henderson o9.5 Pts-122
0.82u
Lock & Cash
Lock & Cash
Last 30d: 32-20-1 (+8.9u)
S.Henderson o9.5 Pts-120
0.83u
Matt Moore
Matt Moore
Last 30d: 78-76-2 (+3.5u)
Under 219.5+104
0.57u
Buckets Podcast
Buckets Podcast
Last 30d: 94-129-7 (-18.0u)
S.Henderson o10.5 Pts-105
0.95u
@HPBasketball ⭐️ https://myaction.app/FkzZMckow2b
RoyalsProps
RoyalsProps
Last 30d: 82-49-7 (+29.0u)
J.Holiday o5.5 Ast-115
1u
Ryan Minion
Ryan Minion
Last 30d: 325-387-11 (-2.4u)
V.Wembanyama o2.5 3pt M+122
$1.00
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 246-313-16 (+5.4u)
D.Clingan o9.5 Pts+110
0.25u
#EV Pinny -106 BM -105 BO -110
T.Camara o4.5 Rebs+108
0.33u
#EV Pinny -110 BM -110 BO -103
OldSchool0909
Last 30d: 120-150-0 (-6.2u)
POR +11.5-113
0.88u
Gilles Gallant
Gilles Gallant
Last 30d: 48-50-0 (-1.4u)
D.Avdija u24.5 Pts-120
0.5u
This one fell hard in G1 but I’m still dubious that Deni can do it again in G2.
Ryan Minion
Ryan Minion
Last 30d: 325-387-11 (-2.4u)
SAS -10.5-110
$1.10
Kalshi
SAS -11-114
$1.14

Trail Blazers vs. Spurs Previews & Analysis

  • Blazers vs Spurs Game 2: Moore's Prop Bet & Over/Under Pick for Tonight's Matchup article feature image

    Blazers vs Spurs Game 2: Moore's Prop Bet & Over/Under Pick for Tonight's Matchup

    Matt Moore•
    Apr 21, 2026 UTC
  • 3 NBA Player Props for Tuesday's Playoff Games article feature image

    3 NBA Player Props for Tuesday's Playoff Games

    Ameer Tyree•
    Apr 21, 2026 UTC
  • NBA 3-Point Props: Our 3 Picks for Tonight article feature image

    NBA 3-Point Props: Our 3 Picks for Tonight

    Action Network Staff•
    Apr 21, 2026 UTC
  • NBA Game Leader Bets: Arinze's 3 Picks for Tuesday article feature image

    NBA Game Leader Bets: Arinze's 3 Picks for Tuesday

    Michael Arinze•
    Apr 21, 2026 UTC
See more NBA Coverage Right Arrow

Prop Odds Comparison

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No props found

Line Movement Tracker

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Trail Blazers vs. Spurs Public Betting Percentages

Away Logo

Trail Blazers

Public

Home Logo

Spurs

36%

Bets%

64%

Money%

NBA Public Betting Right Arrow

Betting Trends

  • Spurs are 3-2 in their last 5 games.
  • Spurs are 3-2 in their last 5 games against the spread
  • Spurs are 24-18 in their road games against the spread
  • The totals have gone OVER in 3 of Spurs' last 5 games
  • The totals have gone OVER in 18 of Spurs' 40 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Spurs		46-35-222-17-124-18-133-29-213-6
Trail Blazers		44-3825-1619-2220-1824-20

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Spurs		36-46-118-2218-24-129-34-17-12
Trail Blazers		43-3925-1618-2325-1318-26

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Spurs		6-2N/AN/A50-1412-7
Trail Blazers		1-4N/AN/A28-1014-30

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 20thPORW 111-98-12.5 WU 222.5SAS -700
Apr 13thDENL 118-128-10 LO 235DEN -450
Apr 11thDALW 139-120-18.5 WO 236.5SAS -2400
Apr 9thPORW 112-101-3 WU 229.5SAS -155
Apr 7thPHIW 115-102-8.5 WU 237SAS -360

Trail Blazers vs. Spurs Injury Updates

Trail Blazers Injuries

  • Damian Lillard
    PG

    Lillard is out with achilles

    Out

  • Shaedon Sharpe
    PG

    Sharpe is questionable with leg

    Questionable

Spurs Injuries

  • Victor Wembanyama
    SF

    Wembanyama is questionable with concussion

    Questionable

  • David Jones Garcia
    PG

    Jones Garcia is out with ankle

    Out

See more NBA Injuries Right Arrow
Player Stats
  • scoring
    Stephon Castle logo
    Stephon Castle
    18
    ppg
  • rebounding
    Devin Vassell logo
    Devin Vassell
    12
    rpg
  • assists
    Stephon Castle logo
    Stephon Castle
    5
    apg
  • shooting
    Luke Kornet logo
    Luke Kornet
    80
    fg%
Team Stats

38-90 (42%)
Field Goals
38-86 (44%)
17-23 (74%)
Free Throws
20-28 (71%)
13-38 (34%)
3P
7-24 (29%)
43
Rebounds
45
18
Assists
19
Turnovers
7
Steals
13
10
Blocks
6
23
Fouls
21

Trail Blazers vs. Spurs Odds Comparison

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Trail Blazers at Spurs Team Totals

MatchupOverUnder
Trail Blazers
1-4
N/A
N/A
Spurs
4-1
N/A
N/A