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Trail Blazers vs Spurs Prediction, Picks, NBA Playoffs Game 2 Odds

Trail Blazers vs Spurs Prediction, Picks, NBA Playoffs Game 2 Odds article feature image
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Scott Wachter-Imagn Images. Pictured: Scoot Henderson, Victor Wembanyama

The Western Conference opening round continues this Tuesday, April 21, as the San Antonio Spurs (1-0) look to build on their series lead against the Portland Trail Blazers (0-1). Game 2 is scheduled for 8:00 p.m. ET from the Frost Bank Center in San Antonio, with the action airing live on NBC and streaming on Peacock.

Oddsmakers see the Spurs as 11-point home favorites in Game 2 tonight, while the over/under is set at 220.5 total points. San Antonio is a -700 moneyline favorite to take a 2-0 lead, while Portland is a +500 underdog to steal a road win and tie the series.

Let’s dive into my Trail Blazers vs. Spurs predictions and NBA bets for tonight's playoff game.


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Trail Blazers vs Spurs Game 2 Predictions

Trail Blazers vs Spurs picks: Under 220.5 (-110), Scoot Henderson Over 10.5 Points (-105)

My Spurs vs. Trail Blazers best bets for Game 2 are on Scoot Henderson to score over 10.5 points and the game to stay under 220.5 total points. Make sure to find the best odds by checking our live NBA odds page.


Trail Blazers vs Spurs Odds

Trail Blazers Logo
Tuesday, April 21
8 p.m. ET
NBC/Peacock
Spurs Logo
Trail Blazers Odds
SpreadTotalMoneyline
+11
-110
220.5
-110o / -110u
+500
Spurs Odds
SpreadTotalMoneyline
-11
-110
220.5
-110o / -110u
-700
Odds via bet365. Get up-to-the-minute NBA odds here.
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Portland Trail Blazers vs San Antonio NBA Preview

In the NBA Playoffs, 2-seeds are 20-5 straight up and 13-12 against the spread in Game 2 after covering in Game 1. That ATS number isn’t exactly sterling, but at least it provides some evidence that 2-seeds don’t always give it right back.

To be honest, I don’t know what to do with the spread. On the one hand, the Blazers have shot the ball well since the All-Star break, and then shot terribly in Game 1. On the other, the Spurs’ perimeter defense is excellent.

The Spurs also got an outlier 3-point shooting performance from Victor Wembanyama last game. However, Portland still hung around and had chances to cover the number, but the Blazers just couldn’t get shots to fall.

I’m not interested in betting the spread in this game. Literally, nothing would surprise me.

You name it: maybe we'll get a close Blazers win against a stunned Spurs team where everything went so well initially, or a bigger Spurs blowout as their confidence grows, or a narrow Spurs win inside the number that presents real questions about Game 3. I could make the case for all of these scenarios.

I think it’s better to stay away from the spread, but my lean is to the Spurs based on their ability to handle the limited offensive weapons that the Blazers possess.


Trail Blazers vs Spurs Picks, Betting Analysis

Under 220.5

I think targeting the Under is the best play. This total opened 221 and we’re tracking the majority of tickets and money on the Over — and yet, this number has moved down two points. That sharp action, combined with San Antonio’s rock solid perimeter defense gives me confidence they’ll keep the Blazers down.

Wembanyama likely won’t shoot that well from deep again, and Stephon Castle may struggle again as he continues to get his playoff feet wet.

Scoot Henderson Over 10.5 Points

Scoot Henderson was tremendous for the Blazers in the series opener. He looked as comfortable and confident as I’ve ever seen him last game. He’s gone over this line in 80% of his last 20 games, and I think his skillset in transition will continue to be effective against the Spurs.

Trail Blazers vs Spurs Betting Predictions

  • Under 220.5 (-110)
  • Scoot Henderson Over 10.5 Points (-105)
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Trail Blazers vs Spurs Betting Trends


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