Cavaliers vs. Knicks Odds & Betting Predictions - October 22, 2025

Cavaliers at Knicks

11:00 pm • ESPN

Cleveland Cavaliers

0-0

111

111 - 119

New York Knicks

0-0

119

MatchupOpenSpreadTotalMoneyline
Cavaliers 0-0	+4	-1.5-112	o229.5-107	-122
Knicks 0-0	u229	+1.5-107	u229.5-113	+110

Wednesday 11:00 p.m.

October 22, 2025

Madison Square GardenNew York

J.Tyson o15.5 Pts+Rebs+Ast-125

0.63u

Tailing my guys @TurveyBets and @kylemurray03

J.Tyson o15.5 Pts+Rebs+Ast-125

0.7u

Love it @kylemurray03

J.Tyson o15.5 Pts+Rebs+Ast-129

1.29u

E.Mobley o17.5 Pts-125

0.2u

CLE +110

X: PicksOffice

Over 226.5-110

0.91u

X: PicksOffice

E.Mobley o17.5 Pts-125

0.48u

L.Ball u11.5 Pts+Ast-124

0.32u

L.Ball o3.5 Ast-102

0.98u

L.Ball o3.5 Ast-113

0.88u

NYK +140

0.14u

Can’t get here on the number.

K.Towns o11.5 Rebs-122

@ChicagoFlow ⭐️⭐️⭐️ https://myaction.app/e5jJG5lYFXb

K.Towns o35.5 Pts+Rebs+Ast-105

@kylemurray03 ⭐️⭐️ and @JoeDellera ⭐️ https://myaction.app/e5jJG5lYFXb

D.Hunter o3.5 Rebs-102

0.5u

@kylemurray03 ⭐️ https://myaction.app/e5jJG5lYFXb

K.Towns o35.5 Pts+Rebs+Ast-115

0.58u

#Tailing @JoeDellera

L.Ball o4.5 Ast+215

0.54u

L.Ball o3.5 Ast+104

0.78u

Garland/Strus are both out, which makes Zo the secondary BH/facilitator after Mitchell. Zo will be in that Ty Jerome role from last season that we always played when one of Mitchell/Garland were out and his assist lines were usually set to 4.5/5.5 and Zo is a much better passer/facilitator. In preseason, Zo has had games of 9 and 3 AST when playing 15+ minutes. He got up to 20 MIN in the last preseason game and with how thin CLE are to start (Hunter questionable) he could see upwards of 25 MIN. His minutes will stagger with Mitchell making him the lead BH at times, fully running the offense. After the last preseason game, Atkinson had a ton of praise for Lonzo’s passing ability and floor vision. He also said he wants Zo taking those risks with his passing. Mike Brown also wants the Knicks to play faster, which will open up more transition looks and possessions in the game.

K.Towns o35.5 Pts+Rebs+Ast-105

The Knicks start off the season against the Cleveland Cavaliers and will be without both Josh Hart and Mitchell Robinson. They also have a new coach in Mike Brown as this team tries to find a new identity. KAT’s role in the offense is a bit in flux but that’s also because he’s going to be used different under Brown than he was under Thibs. I expect a few more possessions with him as a hub offensively which should help the dimes as well as giving him opportunities to score off the dribble. Without Mitch and Hart, he should dominate on the glass for New York even with the Cavs double big lineup. While there may be reduced minutes under Brown, I don’t expect it to take him below 32 minutes per game. I’ll back KAT in the opener.

M.Bridges o16.5 Pts-102

1.02u

K.Towns o35.5 Pts+Rebs+Ast-105

1.05u

D.Hunter o3.5 Rebs-102

1.02u

J.Clarkson o10.5 Pts-112

M.Bridges u3.5 Rebs+100

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NBA Public Betting

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Knicks	N/A	N/A	N/A	N/A	N/A
Cavaliers	N/A	N/A	N/A	N/A	N/A

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Knicks	N/A	N/A	N/A	N/A	N/A
Cavaliers	N/A	N/A	N/A	N/A	N/A

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Knicks	N/A	N/A	N/A	N/A	N/A
Cavaliers	N/A	N/A	N/A	N/A	N/A

date	opponent	score	spread	over/under	moneyline
Oct 17th	CHA	W 113-108	-5.5 L	U 226.5	NYK -220
Oct 13th	WAS	L 103-120	-5 L	O 221.5	WAS -218
Oct 9th	MIN	W 100-95	-4.5 W	U 226.5	NYK -192
Oct 4th	@PHI	W 113-104	-7 W	O 215.5	NYK -270
Oct 2nd	PHI	W 99-84	-6.5 W	U 222	NYK -250