The NBA is back in action, with 12 games on the board tonight.
Our NBA player props for tonight's matchup are targeting Khris Middleton, Karl-Anthony Towns and LaMelo Ball.
Continue below for our NBA player props for Wednesday, October 22.
NBA Player Props for Wednesday, October 22
- Khris Middleton Over 21.5 Points, Rebounds, & Assists (-110)
- Karl-Anthony Towns Over 35.5 Points, Rebounds, & Assists (-105)
- LaMelo Ball Over 29.5 Points & Assists (-115)

Khris Middleton Over 21.5 Points, Rebounds, & Assists (-110)
Wizards vs Bucks, 8 p.m. ET

By Nick Galaida
After getting traded to the Wizards last season, Middleton averaged only 10.7 points in 22.1 minutes per game on 41.3% shooting from the field.
It goes without saying that neither Middleton nor the Wizards had much interest in leveraging his talents on the court down the stretch last season.
Fast forward to opening night this season, and it's likely to be a slightly different story.
In each of his two preseason games, Middleton played 24 minutes, which should translate to closer to 30 minutes in the regular season.
If that is the case, this number is too low for a player who is capable of filling up the stat sheet in numerous ways.
It wouldn't be shocking to see Middleton clear this number with points alone, but he's also a solid rebounder and more than willing to facilitate, too.
Pick: Khris Middleton Over 21.5 Points, Rebounds, & Assists (-110)

Karl-Anthony Towns Over 35.5 Points, Rebounds, & Assists (-105)
Cavaliers vs Knicks, 7 p.m. ET

By Kyle Murray
This is a good spot for KAT, who will benefit from a rebounding perspective with Mitch Robinson and Josh Hart out.
He also projects for 24.9 points and 2.8 assists for me.
His total PRA projection comes out to 41.3.
So, I will happily take the over on this number at 35.5 to start the season.
Pick: Karl-Anthony Towns o35.5 Points, Rebounds, & Assists (-105)

LaMelo Ball Over 29.5 Points & Assists (-115)
Nets vs Hornets, 7 p.m. ET

By Kyle Murray
The Nets had a better defense last season than some might expect, despite their poor season overall.
However, this number still projects well for Ball, as I have him projected for 26.4 points and eight assists.
The Hornets want to run-and-gun and take as many 3-pointers as possible, and that should benefit Ball from a volume perspective, not only with his 3-point attempts but also his assist chances.
Pick: LaMelo Ball Over 29.5 Points & Assists (-115)