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76ers vs. Celtics Odds & Betting Predictions - October 22, 2025

76ers at Celtics

11:30 pm • NBCS-BOS

Philadelphia 76ers

31-26
117
117 - 116

Boston Celtics

37-19
116

76ers at Celtics Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
76ers
31-26
+2.5
+5.5-112
o230.5-108
+166
Celtics
37-19
u225
-5.5-109
u230.5-112
-198
location pinWednesday 11:30 p.m.
October 22, 2025
TD GardenBoston
76ers vs. Celtics Expert Picks
YBK Picks.com
Last 30d: 4-6-0 (-3.5u)
Over 229.5-105
1.9u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 116-141-0 (-40.3u)
J.Embiid u33.5 Pts+Rebs-110
0.45u
Picks Office
Picks Office
Last 30d: 191-133-3 (+44.4u)
BOS -4.5-110
1u
3.5
Under 228.5-110
1u
X: PicksOffice
Scott Rickenbach
Scott Rickenbach
Last 30d: 91-98-1 (-18.5u)
PHI +4.5-110
0.91u
Babs .
Babs .
Last 30d: 27-15-0 (+10.2u)
S.Hauser o9.5 Pts-108
1u
Sir Lockselot
Sir Lockselot
Last 30d: 28-57-1 (-16.3u)
J.Embiid Double-Double (Yes)+122
2u
📚Player Profit 🔑 J.Embiid Double-Double +122 (Player Profit) 2u You will not get better odds ROS than this. He may not play 30+ minutes but he can do this in 15 minutes. He almost had a trip dub the last preseason game in 14 minutes…i love this one Code: sirlocks for 10% off when you get funded at https://www.playerprofit.com/
Mjaybrod
Mjaybrod
Last 30d: 60-41-0 (+19.7u)
Over 229-105
0.95u
Awfully high for this matchup plus no Tatum
Sir Lockselot
Sir Lockselot
Last 30d: 28-57-1 (-16.3u)
PHI +160
3.2u
📚Player Profit 🔑 Sixers ML +160 (Player Profit) 2u If you didn’t think this was coming, idek what to tell you. I’m not sure i should get my hopes up too much but they are at peak level rn. Embiid looks great and back in shape, Maxey is stud, VJ gonna be a stud, Grimes is a bucket, Oubre is a vibe…just feels like it’s all coming together. Best odds we will get all year, jump on it. Code: sirlocks for 10% off when you get funded at https://www.playerprofit.com/
Matt Moore
Matt Moore
Last 30d: 39-32-1 (+2.9u)
J.Embiid o33.5 Pts+Rebs-110
0.25u
Tailing @ChicagoFlow
Matt DiLeo
Matt DiLeo
Last 30d: 32-29-1 (+1.7u)
J.Embiid o4.5 Ast-129
1u
Buckets Podcast
Buckets Podcast
Last 30d: 68-62-4 (-0.5u)
J.Embiid o34.5 Pts+Rebs-114
0.75u
@ChicagoFlow ⭐️⭐️ https://myaction.app/e5jJG5lYFXb
Doug Ziefel
Doug Ziefel
Last 30d: 151-164-2 (-6.6u)
T.Maxey u25.5 Pts-115
0.58u
C.Boucher o8.5 Pts-110
0.55u
DeadPresPicks
DeadPresPicks
Last 30d: 4-10-0 (-4.5u)
J.Embiid o33.5 Pts+Rebs-125
0.45u

76ers vs. Celtics Previews & Analysis

  • NBA Best Bets: 2 Picks for the Late Slate article feature image

    NBA Best Bets: 2 Picks for the Late Slate

    Action Network Staff•
    Oct 22, 2025 UTC
  • 76ers vs Celtics Parlay: +253 SGP for Tonight article feature image

    76ers vs Celtics Parlay: +253 SGP for Tonight

    Chilly Bets•
    Oct 22, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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76ers vs. Celtics Public Betting Percentages

Away Logo

76ers

Public

Home Logo

Celtics

53%

Bets%

47%

Money%

NBA Public Betting Right Arrow

Betting Trends

  • Celtics are 4-1 in their last 5 games.
  • Celtics are 3-2 in their last 5 games against the spread
  • Celtics are 19-10 in their road games against the spread
  • The totals have gone OVER in 2 of Celtics' last 5 games
  • The totals have gone OVER in 10 of Celtics' 27 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Celtics		32-2413-1419-1022-1910-5
76ers		31-25-113-1718-8-118-1313-12-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Celtics		21-3510-1711-1815-266-9
76ers		30-2716-1414-1317-1413-13

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Celtics		37-19N/AN/A29-128-7
76ers		31-26N/AN/A22-99-17

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 15thTORW 110-108-5 LU 232BOS -170
Oct 12thCLEW 138-107-7.5 WO 231.5BOS -285
Oct 10th@TORL 105-107-2.5 LU 229TOR -148
Oct 9th@MEMW 121-103-4 WU 232BOS -160
Jul 20thATLW 101-80+1 WU 185.5BOS -105

Celtics vs. 76ers Injury Updates

Celtics Injuries

  • Jaylen Brown
    SF

    Jaylen Brown (knee) out Tuesday.

    Out

  • Jayson Tatum
    PF

    Tatum is out with achilles

    Out

76ers Injuries

  • Joel Embiid
    C

    Embiid is questionable with conditioning

    Questionable

  • Paul George
    PF

    George is out with suspension

    Out

See more NBA Injuries Right Arrow
Player Stats
  • scoring
    Derrick White logo
    Derrick White
    25
    ppg
  • rebounding
    Neemias Queta logo
    Neemias Queta
    8
    rpg
  • assists
    Derrick White logo
    Derrick White
    4
    apg
  • shooting
    player logo
    -
    100
    fg%
Team Stats

39-85 (46%)
Field Goals
41-91 (45%)
23-30 (77%)
Free Throws
23-26 (88%)
16-40 (40%)
3P
11-43 (26%)
40
Rebounds
42
23
Assists
16
Turnovers
3
Steals
7
4
Blocks
4
23
Fouls
28

76ers vs. Celtics Odds Comparison

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76ers at Celtics Team Totals

MatchupOverUnder
76ers
31-26
N/A
N/A
Celtics
37-19
N/A
N/A