Reds vs. Cubs Odds & Betting Predictions - May 6, 2026

Reds at Cubs

11:40 pm • MARQ

Cincinnati Reds

20-16

6 - 6

Chicago Cubs

24-12

MatchupOpenSpreadTotalMoneyline
Reds 20-16	+1.5	+1.5-150	o8-115	+145
Cubs 24-12	u8.5	-1.5+125	u8-105	-169

Wednesday 11:40 p.m.

May 06, 2026

Wrigley FieldChicago

C.Rea u4.5 Ks+107

0.5u

Under 8.5-111

Under 0.5 (1st Inn)-130

1.3u

S.Suzuki o1.5 Hits + Runs + RBIs-122

1.22u

Under 8-105

1.05u

CHC -168

(FD) This is mostly a bet against Singer, who has been awful (4.84 SIERA/6.18 xERA). Rea has bee more than a run better (3.57/4.43). I also give the Cubs a near 30 point wRC+ edge (127/116 Hm/v RHP vs 79/91 – proj. LU 121 vs 97 vs RHP since LY). Proj. defense 19 FRV edge for CHC and bullpen estimators full run better. I have full game and F5 rated evenly. Flip a coin. Split it. (Good to -180)

Under 8.5-125

0.63u

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No props found

MLB Public Betting

Cubs are 5-0 in their last 5 games.
Cubs are 2-3 in their last 5 games against the spread
Cubs are 6-9 in their road games against the spread
The totals have gone OVER in 2 of Cubs' last 5 games
The totals have gone OVER in 11 of Cubs' 21 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cubs	17-19	11-10	6-9	11-12	6-7
Reds	22-14	10-8	12-6	6-3	16-11

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cubs	22-14	11-10	11-4	12-11	10-3
Reds	21-14-1	13-5	8-9-1	6-3	15-11-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cubs	24-12	16-5	8-7	17-6	7-6
Reds	20-16	10-8	10-8	6-3	14-13

date	opponent	score	spread	over/under	moneyline
May 5th	CIN	W 3-2	-1.5 L	U 8	CHC -165
May 4th	CIN	W 5-4	-1.5 L	U 11.5	CHC -220
May 3rd	ARI	W 8-4	-1.5 W	O 11.5	CHC -157
May 2nd	ARI	W 2-0	-1.5 W	U 7	CHC -170
May 1st	ARI	W 6-5	-1.5 L	O 7	CHC -149

Nick Lodolo
SP
Lodolo is out with finger
Out
Hunter Greene
SP
Greene is out with elbow
Out

Tyler Austin
1B
Austin is out with knee
Out
Justin Steele
SP
Steele is out with elbow
Out
Jordan Wicks
SP
Wicks is out with arm
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RB.Singer, P	96	6	6	4
LS.Moll, P	11	0.2	0	0
RP.Johnson, P	5	0.1	0	0
RT.Antone, P	12	1	2	0
RG.Ashcraft, P	27	0.2	1	2

HITTERS	H-AB	R	HR	RBI
1T.Friedl, CF	1-3	1	0	0
1D.Myers, PH	0-1	0	0	0
1D.Myers, CF	0-1	0	0	0
2J.Bleday, LF	2-5	0	0	1
3E.De La Cruz, SS	0-4	0	0	3
4S.Stewart, 3B	0-4	0	0	0
4K.Hayes, 3B	-
5N.Lowe, DH	1-4	0	0	0
6S.Steer, 1B	1-4	1	1	1
7W.Benson, RF	2-3	1	0	0
8J.Trevino, C	0-3	0	0	0
8T.Stephenson, PH	1-1	1	0	0
8T.Stephenson, C	1-1	1	0	0
9M.McLain, 2B	2-3	2	1	1

PITCHER	PC	IP	K	ER
RC.Rea, P	98	5.1	5	1
RJ.Webb, P	14	1.2	1	0
RP.Maton, P	12	1	1	0
RC.Martin, P	11	0	0	3
LH.Milner, P	21	1	1	1

HITTERS	H-AB	R	HR	RBI
1N.Hoerner, 2B	0-4	0	0	0
2M.Ballesteros, DH	0-3	0	0	0
2M.Shaw, PH	-
2M.Conforto, PH	0-1	0	0	0
2M.Conforto, DH	0-1	0	0	0
3A.Bregman, 3B	1-4	1	0	0
4I.Happ, LF	3-4	2	1	2
5S.Suzuki, RF	1-4	1	0	1
6M.Busch, 1B	1-3	0	0	0
7C.Kelly, C	1-4	1	0	0
8P.Crow-Armstrong, CF	2-3	1	1	2
9D.Swanson, SS	1-4	0	0	0