Pirates vs. Cardinals Odds & Betting Predictions - May 6, 2025

Pirates at Cardinals

11:45 pm • FDSMW
1 - 2
Starting Pitchers
pitcherteameraw-l
Matthew Liberatore logoM.LiberatoreSt. Louis Cardinals logo4.046-8
Paul Skenes logoP.SkenesPittsburgh Pirates logo1.915-8

Pirates at Cardinals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Pirates
43-62
-1.5
-1.5+145
o7-118
-118
Cardinals
54-52
u7
+1.5-175
u7-102
+100
location pinTuesday 11:45 p.m.
May 06, 2025
Busch StadiumSt. Louis
Pirates vs. Cardinals Expert Picks
Steak Friend
Steak Friend
Last 30d: 0-0-0 (+0.0u)
STL +100
1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 53-51-1 (+13.1u)
Under 3.5 (F5)+100
1u
Markus Markets
Markus Markets
Last 30d: 11-20-3 (-1.5u)
J.Triolo u1.5 Hits + Runs + RBIs-160
0.63u
Sandy Plashkes
Sandy Plashkes
Last 30d: 79-67-2 (+20.8u)
P.Skenes o6.5 Ks+126
1u
Billy Ward
Billy Ward
Last 30d: 15-17-0 (-1.3u)
Under 0.5 (1st Inn)-145
1u
DK line
Jim Sannes
Jim Sannes
Last 30d: 21-52-0 (-14.5u)
M.Liberatore o5.5 Ks+148
1.48u
in the alt. market on FanDuel. Liberatore has been increasing his curve usage in recent starts, which has allowed him to get more whiffs against righties. He had seven strikeouts against the Pirates earlier this year, and their active roster has a 24.7% strikeout rate against lefties since the start of last year.
Boomer Betz
Boomer Betz
Last 30d: 235-244-4 (+1.3u)
PIT -125
1u
Sean Zerillo
Sean Zerillo
Last 30d: 157-164-11 (+7.7u)
STL +115
0.58u
Bet to +110

Pirates vs. Cardinals Previews & Analysis

  • Zerillo's Tuesday MLB Predictions & Betting Card article feature image

    Zerillo's Tuesday MLB Predictions & Betting Card

    Sean Zerillo
    May 6, 2025 UTC
  • Pirates vs Cardinals: Razor Thin Margins article feature image

    Pirates vs Cardinals: Razor Thin Margins

    Collin Whitchurch
    May 6, 2025 UTC
  • 3 MLB NRFI & YRFI Picks for Tuesday article feature image

    3 MLB NRFI & YRFI Picks for Tuesday

    Billy Ward
    May 6, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Pirates vs. Cardinals Public Betting Percentages

Away Logo

Pirates

Public

53%

Bets%

47%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cardinals
56-5029-2327-2721-2834-22
Pirates
55-5032-2323-2710-2043-30

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cardinals
54-47-528-22-226-25-325-20-428-27-1
Pirates
40-60-523-29-317-31-211-1928-40-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cardinals
54-5231-2123-3126-2327-29
Pirates
43-6230-2513-3713-1729-44

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 5thPITW 6-3-1.5 WO 8.5STL -132
May 4thNYMW 5-4+1.5 WO 7.5STL +136
May 4thNYMW 6-5+1.5 WO 8.5STL +102
May 3rdNYML 3-9+1.5 LO 7.5NYM +100
May 1st@CINL 1-9---

Cardinals vs. Pirates Injury Updates

Cardinals Injuries

  • Nolan Gorman
    2B

    Gorman is out with back

    Out

Pirates Injuries

  • Johan Oviedo
    SP

    Oviedo is questionable with elbow

    Questionable

  • Endy Rodriguez
    1B

    Rodriguez is out with elbow

    Out

  • Jared Jones
    SP

    Jones is out with elbow

    Out

  • Jared Triolo
    SS

    Triolo is questionable with back

    Questionable

  • Spencer Horwitz
    1B

    Horwitz is questionable with wrist

    Questionable

Pirates vs. Cardinals Box Score
Pirates Player Stats
Projected
PITCHERPCIPKER
Paul Skenes logoRP.Skenes, P102662
Dennis Santana logoRD.Santana, P14110
David Bednar logoRD.Bednar, P15110
HITTERSH-ABRHRRBI
Oneil Cruz logo1O.Cruz, CF0-3100
Bryan Reynolds logo2B.Reynolds, RF0-4000
Andrew McCutchen logo3A.McCutchen, DH1-3000
Ke'Bryan Hayes logo4K.Hayes, 3B2-4001
Alexander Canario logo5A.Canario, LF0-3000
Adam Frazier logo5A.Frazier, PH0-1000
Matt Gorski logo6M.Gorski, 1B0-3000
Enmanuel Valdez logo6E.Valdez, PH0-1000
Jared Triolo logo7J.Triolo, SS0-3000
Joey Bart logo7J.Bart, PH0-1000
Liover Peguero logo8L.Peguero, 2B1-3000
Henry Davis logo9H.Davis, C0-2000
Cardinals Player Stats
Projected
PITCHERPCIPKER
Matthew Liberatore logoLM.Liberatore, P99781
Steven Matz logoLS.Matz, P18110
Gordon Graceffo logoRG.Graceffo, P6100
HITTERSH-ABRHRRBI
Lars Nootbaar logo1L.Nootbaar, LF0-3000
Masyn Winn logo2M.Winn, SS0-4000
Brendan Donovan logo3B.Donovan, 2B1-4000
Nolan Arenado logo4N.Arenado, 3B1-4100
Willson Contreras logo5W.Contreras, DH0-1100
Alec Burleson logo6A.Burleson, 1B1-3002
Yohel Pozo logo7Y.Pozo, C0-3000
Jordan Walker logo8J.Walker, RF0-2000
Victor Scott logo9V.Scott, CF1-3000

Pirates vs. Cardinals Odds Comparison

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Pirates at Cardinals Team Totals

MatchupOverUnder
Pirates
43-62
o3.5-118
u3.5-110
Cardinals
54-52
o3.5+105
u3.5-140