Padres vs. Giants Odds & Betting Predictions - May 6, 2026

Padres at Giants

7:45 pm • NBCS-BA

San Diego Padres

22-14

5 - 1

San Francisco Giants

14-23

pitcher		team	era	w-l
A.Houser			6.19	0-4
B.Rodriguez			1.53	0-1

MatchupOpenSpreadTotalMoneyline
Padres 22-14	-1.5	-1.5+159	o8.5-105	-102
Giants 14-23	u8.5	+1.5-195	u8.5-112	-118

Wednesday 7:45 p.m.

May 06, 2026

Oracle ParkSan Francisco

M.Waldron o3.5 Ks+124

SF -102

1.02u

SD -105

0.95u

Join Discord for earlier access: https://discord.gg/HjKxYKdSUy San Diego is 21-14 and only 0.5 games off the NL West lead against a 14-22 Giants team sitting 8 games back. The Padres already put 10 on this same park today with a 14-hit attack, so the near pick'em price is hard to ignore. Both starters are still TBD, which keeps this on the cleaner team profile instead of a forced pitching story.

A.Houser u3.5 Ks-120

0.74u

#EV 5.92%

SF -0.5 (F5)+132

0.66u

#EV 3.51%

McGrath's Projection for Padres-Giants
Tanner McGrath•
May 6, 2026 UTC

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No props found

MLB Public Betting

Giants are 1-4 in their last 5 games.
Giants are 2-3 in their last 5 games against the spread
Giants are 7-11 in their road games against the spread
The totals have gone OVER in 1 of Giants' last 5 games
The totals have gone OVER in 8 of Giants' 19 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Giants	15-22	8-11	7-11	4-9	11-13
Padres	21-15	12-7	9-8	12-9	9-6

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Giants	15-20-2	8-10-1	7-10-1	9-4	6-16-2
Padres	16-19-1	10-8-1	6-11	9-11-1	7-8

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Giants	14-23	8-11	6-12	5-8	9-15
Padres	22-14	11-8	11-6	13-8	9-6

date	opponent	score	spread	over/under	moneyline
May 6th	SD	L 5-10	-1.5 L	O 7.5	SD -149
May 5th	SD	W 3-2	+1.5 W	U 8	SF +112
May 3rd	@TB	L 1-2	+1.5 W	U 8	TB +104
May 2nd	@TB	L 1-5	-1.5 L	U 7.5	TB -115
May 1st	@TB	L 0-3	+1.5 L	U 7.5	TB +117

Hayden Birdsong
SP
Birdsong is out with arm
Out

Joe Musgrove
SP
Musgrove is out with elbow
Out
Will Wagner
3B
Wagner is out with oblique
Out

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PITCHER	PC	IP	K	ER
RB.Rodriguez, P	7	1	0	0
RM.Waldron, P	67	5	7	1
LA.Morejon, P	26	2	4	0
RM.Miller, P	13	1	2	0

HITTERS	H-AB	R	HR	RBI
1J.Merrill, CF	1-4	0	0	0
2M.Machado, 3B	0-3	1	0	0
3M.Andujar, DH	0-4	0	0	0
4G.Sheets, 1B	1-3	1	1	1
4X.Bogaerts, SS	1-1	1	1	2
5F.Tatis, 2B	0-4	1	0	0
6R.Laureano, LF	0-2	1	0	0
7N.Castellanos, RF	2-4	0	0	0
8F.Fermin, C	0-4	0	0	0
9S.Song, SS	0-2	0	0	0
9T.France, PH	1-2	0	0	2
9T.France, 1B	1-2	0	0	2

PITCHER	PC	IP	K	ER
RA.Houser, P	74	6	3	1
RK.Winn, P	16	0.2	0	1
LM.Gage, P	10	0.1	0	0
RR.Walker, P	29	1	0	2
RJ.Peguero, P	8	1	1	0

HITTERS	H-AB	R	HR	RBI
1H.Ramos, LF	0-4	0	0	0
2J.Lee, CF	0-4	0	0	0
3C.Schmitt, 2B	0-4	0	0	0
4M.Chapman, 3B	0-3	0	0	0
5R.Devers, 1B	1-3	1	1	1
6W.Adames, SS	0-3	0	0	0
7B.Eldridge, DH	0-3	0	0	0
8J.Rodriguez, RF	2-3	0	0	0
9P.Bailey, C	0-3	0	0	0