Guardians vs. Tigers Odds & Betting Predictions - May 22, 2025

Guardians at Tigers

10:40 pm • CLEG
7 - 0
Starting Pitchers
pitcherteameraw-l
Jack Flaherty logoJ.FlahertyDetroit Tigers logo4.392-6
Tanner Bibee logoT.BibeeCleveland Guardians logo3.574-4

Guardians at Tigers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Guardians
26-22
+1.5
+1.5-200
o8-105
+110
Tigers
33-17
u8.5
-1.5+166
u8-115
-130
location pinThursday 10:40 p.m.
May 22, 2025
Comerica ParkDetroit
Guardians vs. Tigers Expert Picks
The Propfessor
The Propfessor
Last 30d: 27-29-0 (-7.4u)
R.Greene o1.5 Hits + Runs + RBIs-115
1.15u
Greg DiNardo
Greg DiNardo
Last 30d: 78-77-0 (-1.4u)
CLE +105
1u
Steak Friend
Steak Friend
Last 30d: 204-250-3 (-48.3u)
Under 8-109
1u
Cam Is Money
Cam Is Money
Last 30d: 122-125-6 (-4.2u)
K.Carpenter o1.5 Hits + Runs + RBIs-120
1u
The Degenerates
The Degenerates
Last 30d: 78-70-3 (-4.5u)
DET -130
1.3u
Austin Pendergrass
Austin Pendergrass
Last 30d: 90-120-3 (-26.1u)
DET -130
1u
Sir Lockselot
Sir Lockselot
Last 30d: 39-49-0 (+17.3u)
CLE +110
2.2u
🔑 Guadians ML +110 (FanDuel) 2u I can’t quit this team and I love the value here. Line screams Guards imo. 4/L5 Bibee starts have been really strong. Flaherty hasn’t looked right all year and doesn’t go deep into games. Guards have won L2 games vs Tigers too. Let’s get it.
Bet Labs
Bet Labs
Last 30d: 32-31-1 (-3.9u)
Over 8-105
1.05u
Grant Neiffer
Grant Neiffer
Last 30d: 31-122-6 (+20.6u)
K.Manzardo o0.5 HR+575
0.5u
R.Greene o0.5 HR+519
0.19u
Jim Sannes
Jim Sannes
Last 30d: 38-44-0 (+8.3u)
T.Bibee u5.5 Ks-146
1u
Even when I regress Bibee's projected strikeout rate closer to his career baseline, I still have him projected for 4.65 strikeouts tonight. He's throwing a low-whiff sinker a lot this year while throwing fewer cutters and changeups (his two pitches that generated the most whiffs last year). I haven't seen any signs of his stopping that trend yet, so I'm seeing value on the under even at -146.
J.Flaherty o5.5 Ks+106
1.06u
Even in a low-strikeout matchup, I have Flaherty projected at 6.5 strikeouts tonight. Pitchers in that range for me have gone over 5.5 strikeouts 58.7% of the time. Flaherty has gotten six-plus strikeouts in five of nine starts this year and three of four at home.
Brian Bitler
Brian Bitler
Last 30d: 77-85-0 (-19.0u)
CLE +123
3.69u
Scott Rickenbach
Scott Rickenbach
Last 30d: 78-72-2 (-6.1u)
Over 8-103
1u
Moneyline Hacks
Moneyline Hacks
Last 30d: 108-72-3 (+66.4u)
Under 8-115
0.87u
🚨Free analysis & VIP Picks can be found on our Discord. Link: https://discord.gg/A8v49URQaG Link to VIP (Copy &Paste): https://linktr.ee/moneylinehacks%F0%9F%94%A560% OFF with promo code: Hacks60
Sean Zerillo
Sean Zerillo
Last 30d: 134-154-7 (-8.9u)
CLE +128
0.64u
Bet to +120

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Prop Odds Comparison

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Line Movement Tracker

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Guardians vs. Tigers Public Betting Percentages

Away Logo

Guardians

Public

21%

Bets%

79%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Tigers
28-2314-914-1416-1312-9
Guardians
23-2611-1112-159-1014-15

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Tigers
25-22-48-12-317-10-113-13-312-8-1
Guardians
21-25-38-13-113-12-211-810-16-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Tigers
33-1817-616-1222-711-10
Guardians
27-2214-813-1413-614-15

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 21st@STLW 5-1-1.5 WU 9DET -103
May 20th@STLW 5-4-1.5 LO 7.5DET -180
May 19th@STLL 4-11+1.5 LO 8STL +140
May 18th@TORW 3-2+1.5 WU 8.5DET +105
May 17th@TORL 1-2-1.5 LU 8.5TOR -135

Guardians vs. Tigers Injury Updates

Guardians Injuries

  • Shane Bieber
    SP

    Bieber is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

  • David Fry
    C

    Fry is out with elbow

    Out

Tigers Injuries

  • Alex Cobb
    SP

    Cobb is out with hip

    Out

  • Parker Meadows
    CF

    Meadows is out with arm

    Out

  • Wenceel Perez
    RF

    Perez is out with back

    Out

  • Jose Urquidy
    SP

    Urquidy is out with arm

    Out

  • Ty Madden
    SP

    Madden is out with shoulder

    Out

  • Sawyer Gipson-Long
    SP

    Gipson-Long is out with groin

    Out

Guardians vs. Tigers Box Score
Guardians Player Stats
Projected
PITCHERPCIPKER
Tanner Bibee logoRT.Bibee, P96780
Tim Herrin logoLT.Herrin, P13000
Cade Smith logoRC.Smith, P15130
Matt Festa logoRM.Festa, P7110
HITTERSH-ABRHRRBI
Steven Kwan logo1S.Kwan, LF1-5000
Lane Thomas logo2L.Thomas, CF0-4001
Jose Ramirez logo3J.Ramirez, 3B2-5100
Kyle Manzardo logo4K.Manzardo, DH0-3100
Carlos Santana logo5C.Santana, 1B1-2102
Daniel Schneemann logo6D.Schneemann, SS0-3100
Bo Naylor logo7B.Naylor, C0-3100
Angel Martinez logo8A.Martinez, 2B2-4213
Nolan Jones logo9N.Jones, RF0-2000
Jhonkensy Noel logo9J.Noel, PH0-2000
Jhonkensy Noel logo9J.Noel, RF0-2000
Tigers Player Stats
Projected
PITCHERPCIPKER
Jack Flaherty logoRJ.Flaherty, P1086.283
Sean Guenther logoLS.Guenther, P251.112
John Brebbia logoRJ.Brebbia, P17111
HITTERSH-ABRHRRBI
Kerry Carpenter logo1K.Carpenter, RF1-3000
Justyn-Henry Malloy logo1J.Malloy, PH1-1000
Justyn-Henry Malloy logo1J.Malloy, RF1-1000
Gleyber Torres logo2G.Torres, 2B0-2000
Andy Ibanez logo2A.Ibanez, 2B0-1000
Akil Baddoo logo2A.Baddoo, PH0-1000
Akil Baddoo logo2A.Baddoo, LF0-1000
Zach McKinstry logo3Z.McKinstry, 3B0-4000
Riley Greene logo4R.Greene, LF0-4000
Riley Greene logo4R.Greene, CF0-4000
Spencer Torkelson logo5S.Torkelson, 1B0-3000
Colt Keith logo6C.Keith, DH0-4000
Dillon Dingler logo7D.Dingler, C1-4000
Trey Sweeney logo8T.Sweeney, SS0-2000
Javier Baez logo9J.Baez, CF2-3000
Javier Baez logo9J.Baez, 2B2-3000

Guardians vs. Tigers Odds Comparison

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Guardians at Tigers Team Totals

MatchupOverUnder
Guardians
26-22
N/A
N/A
Tigers
33-17
N/A
N/A