Guardians vs. Reds Odds & Betting Predictions - May 16, 2025
Guardians at Reds
9:10 pm • CLEGStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 4.03 | 14-12 | ||
![]() | 4.25 | 12-11 |
Guardians at Reds Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Guardians 1-2 | -1.5 | -1.5+130 | o9.5+100 | -122 |
Reds 0-2 | u9 | +1.5-156 | u9.5-119 | +102 |

Great American Ball ParkCincinnati
Guardians vs. Reds Expert Picks
The Degenerates
Last 30d: 53-59-0 (-10.6u)
CLE -116 (Live)
1.16u
Wags Wins
Last 30d: 222-214-1 (-3.1u)
Over 9.5-102
1.5u
Greg DiNardo
Last 30d: 0-0-0 (+0.0u)
CLE -121
1.21u
Allan Lem
Last 30d: 139-112-4 (+3.8u)
B.Singer u4.5 Ks+108
0.5u
This one showed up in the ScoresAndOdds model and I like it at plus odds. Cleveland ranks 20th this season in strikeout rate vs RHP (20.7%). Active roster has struck out 15.6% against Singer in their career.
David Payne
Last 30d: 10-12-0 (-2.0u)
K.Manzardo o0.5 HR+310
1u
FD
Grant Neiffer
Last 30d: 43-82-0 (+12.4u)
K.Manzardo o0.5 HR+340
0.5u
Lines at Lunch
Last 30d: 86-103-2 (-24.6u)
Under 9-115
1.15u
Ryan Sura
Last 30d: 91-101-1 (-7.8u)
Under 9-115
1.15u
Matt DiLeo
Last 30d: 45-39-0 (-0.7u)
CLE o1.5 Team Total (F5)-155
0.65u
CLE o2.5 Team Total (F5)+125
0.31u
David Payne
Last 30d: 10-12-0 (-2.0u)
Over 0.5 (1st Inn)-108
1u
FD
Billy Ward
Last 30d: 11-18-0 (-1.4u)
Over 0.5 (1st Inn)+100
1.05u
Brandon Kravitz
Last 30d: 66-89-1 (-14.2u)
Under 8.5+105
1u
Cam Is Money
Last 30d: 81-95-3 (-11.3u)
CLE -118 (F5)
1.18u
David Payne
Last 30d: 10-12-0 (-2.0u)
Over 9-105
1u
DK

Sean Zerillo
Last 30d: 93-107-5 (+7.4u)
Over 9-105
0.53u
Bet to -115
Guardians vs. Reds Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Guardians vs. Reds Public Betting Percentages
Betting Trends
- Reds are 3-2 in their last 5 games.
- Reds are 2-3 in their last 5 games against the spread
- Reds are 42-39 in their road games against the spread
- The totals have gone OVER in 1 of Reds' last 5 games
- The totals have gone OVER in 26 of Reds' 79 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Reds Injury Updates

Guardians Injuries
- Ben LivelySP
Lively is out with elbow
Out
- John MeansSP
Means is out with elbow
Out

Reds Injuries
- Noelvi Marte3B
Marte is day-to-day with side
Day-to-Day
- Reiver SanmartinRP
Sanmartin is out with elbow
Out
- Brandon WilliamsonSP
Williamson is out for season with elbow
Out for Season
- Graham AshcraftRP
Ashcraft is out with groin
Out
- Chase BurnsSP
Burns is out with hip
Out
- Julian AguiarSP
Aguiar is out for season with elbow
Out for Season
- Rhett LowderSP
Lowder is out with elbow
Out
- Carson SpiersRP
Spiers is out with shoulder
Out
Guardians vs. Reds Box Score
Guardians Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 105 | 6 | 4 | 4 | |
![]() | 28 | 2 | 3 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-3 | 1 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 1 | 1 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 2 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 1-3 | 1 | 1 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
Reds Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 90 | 5 | 4 | 3 | |
![]() | 12 | 1 | 0 | 0 | |
![]() | 5 | 1 | 0 | 0 | |
![]() | 11 | 1 | 0 | 1 | |
![]() | 16 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 2-4 | 1 | 1 | 1 |
![]() | 2-4 | 1 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-4 | 1 | 1 | 3 |
![]() | 1-4 | 1 | 0 | 0 |
Guardians vs. Reds Odds Comparison
Could not load odds
Guardians at Reds Team Totals
MatchupOverUnder | ||
|---|---|---|
Guardians 1-2 | o4.5-125 | u4.5-105 |
Reds 0-2 | o4.5+105 | u4.5-135 |



























