Guardians vs. Diamondbacks Odds & Betting Predictions - August 20, 2025

Guardians at Diamondbacks

1:40 am • MLB Network

Cleveland Guardians

1-2

5 - 6

Arizona Diamondbacks

0-0

pitcher		team	era	w-l
E.Rodriguez			5.01	9-9
T.Bibee			4.25	12-11

MatchupOpenSpreadTotalMoneyline
Guardians 1-2	+1.5	-1.5+319	o8.5-121	+100
Diamondbacks 0-0	u9	+1.5-190	u8.5-101	-120

Wednesday 1:40 a.m.

August 20, 2025

Chase FieldPhoenix

ARI -115

1.74u

Arizona has the edge tonight with Tanner Bibee’s biggest weakness exposed. He’s giving up 1.45 HR/9, and Chase Field doesn’t forgive mistakes. One swing from the D-backs middle order can flip this game fast. That’s the cleanest path to a home win. Eduardo Rodríguez isn’t perfect with a 5.40 ERA, but his strikeout punch at 9.08 K/9 gives him the tools to strand runners when needed. If he limits traffic early, he can hand this game to Arizona’s bullpen with a lead, which is all the D-backs need. Series urgency also matters. Arizona already dropped Game 1 and can’t afford to fall behind at home. With the roof closed, no weather randomness plays in. Execution wins, and the D-backs have the power bats and strikeout arm to even this series.

Under 9-120

@Zerillo

Under 9-110

0.55u

Projecting this closer to 8

Under 9-102

0.51u

Bet to -112

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MLB Public Betting

Diamondbacks are 0-5 in their last 5 games.
Diamondbacks are 1-4 in their last 5 games against the spread
Diamondbacks are 42-38 in their road games against the spread
The totals have gone OVER in 3 of Diamondbacks' last 5 games
The totals have gone OVER in 39 of Diamondbacks' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Diamondbacks	82-79	40-41	42-38	36-52	45-27
Guardians	86-76	39-42	47-34	33-36	51-38

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Diamondbacks	80-74-7	39-36-6	41-38-1	43-40-5	37-33-2
Guardians	69-87-6	37-41-3	32-46-3	34-34-1	34-50-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Diamondbacks	80-82	43-38	37-43	45-43	34-38
Guardians	88-74	45-36	43-38	44-25	43-46

date	opponent	score	spread	over/under	moneyline
Aug 19th	CLE	L 1-3	+1.5 L	U 9	CLE -123
Aug 17th	@COL	L 5-6	-1.5 L	U 12	COL -155
Aug 17th	@COL	L 7-10	-1.5 L	O 11.5	COL -175
Aug 16th	@COL	L 3-4	-1.5 L	U 12	COL -199
Aug 15th	@COL	W 8-2	-1.5 W	U 13	ARI -175

Ben Lively
SP
Lively is out with elbow
Out
John Means
SP
Means is out with elbow
Out

John Curtiss
RP
Curtiss is out with elbow
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RT.Bibee, P	92	5.2	5	4
LE.Sabrowski, P	4	0.1	0	0
LT.Herrin, P	12	0.2	0	2
RN.Enright, P	7	0.1	0	0
RJ.Junis, P	8	1	1	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	0-4	0	0	0
2A.Martinez, CF	2-5	1	0	0
3J.Ramirez, 3B	1-3	2	1	2
4D.Fry, DH	0-2	0	0	0
4K.Manzardo, PH	0-2	0	0	0
4K.Manzardo, DH	0-2	0	0	0
5C.Santana, 1B	1-5	1	0	1
6G.Arias, SS	1-4	1	0	0
7N.Jones, RF	2-4	0	0	1
8B.Rocchio, 2B	0-3	0	0	0
9A.Hedges, C	1-3	0	0	1
9B.Naylor, PR	0-0	0	0	0
9B.Naylor, C	0-0	0	0	0

PITCHER	PC	IP	K	ER
LE.Rodriguez, P	96	6.2	4	4
RJ.Burgos, P	4	0.1	0	0
RA.Hoffmann, P	22	0.2	0	1
LK.Backhus, P	11	0.1	0	0
LA.Saalfrank, P	9	1	1	0

HITTERS	H-AB	R	HR	RBI
1G.Perdomo, SS	2-3	2	0	1
2K.Marte, 2B	0-3	0	0	0
3C.Carroll, RF	2-4	2	0	1
4L.Gurriel, DH	1-4	0	0	3
5P.Smith, 1B	1-4	0	0	0
6B.Alexander, 3B	0-3	0	0	0
7J.McCarthy, LF	2-4	1	1	1
8A.Thomas, CF	1-4	1	0	0
9J.Herrera, C	0-3	0	0	0