Guardians vs. Diamondbacks Odds & Betting Predictions - August 20, 2025
Guardians at Diamondbacks
1:40 am • MLB NetworkStarting Pitchers
pitcher | team | era | w-l | |
---|---|---|---|---|
![]() | ![]() | 5.01 | 9-9 | |
![]() | ![]() | 4.25 | 12-11 |
Guardians at Diamondbacks Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Guardians 1-2 | +1.5 | -1.5+319 | o8.5-121 | +100 |
![]() Diamondbacks 0-0 | u9 | +1.5-190 | u8.5-101 | -120 |

Chase FieldPhoenix
Guardians vs. Diamondbacks Expert Picks

Picks Office
Last 30d: 66-80-3 (-10.3u)
ARI -115
1.74u
Arizona has the edge tonight with Tanner Bibee’s biggest weakness exposed. He’s giving up 1.45 HR/9, and Chase Field doesn’t forgive mistakes. One swing from the D-backs middle order can flip this game fast. That’s the cleanest path to a home win.
Eduardo RodrÃguez isn’t perfect with a 5.40 ERA, but his strikeout punch at 9.08 K/9 gives him the tools to strand runners when needed. If he limits traffic early, he can hand this game to Arizona’s bullpen with a lead, which is all the D-backs need.
Series urgency also matters. Arizona already dropped Game 1 and can’t afford to fall behind at home. With the roof closed, no weather randomness plays in. Execution wins, and the D-backs have the power bats and strikeout arm to even this series.

Payoff Pitch Podcast
Last 30d: 66-73-6 (+11.3u)
Under 9-120
1u
@Zerillo

Allan Lem
Last 30d: 121-117-8 (-3.7u)
Under 9-110
0.55u
Projecting this closer to 8

Sean Zerillo
Last 30d: 155-181-6 (-9.3u)
Under 9-102
0.51u
Bet to -112
Guardians vs. Diamondbacks Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Guardians vs. Diamondbacks Public Betting Percentages
Betting Trends
- Diamondbacks are 0-5 in their last 5 games.
- Diamondbacks are 1-4 in their last 5 games against the spread
- Diamondbacks are 42-38 in their road games against the spread
- The totals have gone OVER in 3 of Diamondbacks' last 5 games
- The totals have gone OVER in 39 of Diamondbacks' 81 last games at home
Matchup History
Against the Spread (ATS) History
overall | home | away | favorite | underdog | |
---|---|---|---|---|---|
![]() | 82-79 | 40-41 | 42-38 | 36-52 | 45-27 |
![]() | 86-76 | 39-42 | 47-34 | 33-36 | 51-38 |
Over/Under History
overall | home o/u | away o/u | favorite o/u | underdog o/u | |
---|---|---|---|---|---|
![]() | 80-74-7 | 39-36-6 | 41-38-1 | 43-40-5 | 37-33-2 |
![]() | 69-87-6 | 37-41-3 | 32-46-3 | 34-34-1 | 34-50-5 |
Straight-Up (ML) History
overall | home | away | favorite | underdog | |
---|---|---|---|---|---|
![]() | 80-82 | 43-38 | 37-43 | 45-43 | 34-38 |
![]() | 88-74 | 45-36 | 43-38 | 44-25 | 43-46 |
Last 5 Matchups
Guardians vs. Diamondbacks Injury Updates

Guardians Injuries
- Edward LivelySP
Lively is out with elbow
Out
- John MeansSP
Means is out with elbow
Out

Diamondbacks Injuries
- John CurtissRP
Curtiss is out with elbow
Out
Guardians vs. Diamondbacks Box Score

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 92 | 5.2 | 5 | 4 | |
![]() | 4 | 0.1 | 0 | 0 | |
![]() | 12 | 0.2 | 0 | 2 | |
![]() | 7 | 0.1 | 0 | 0 | |
![]() | 8 | 1 | 1 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-5 | 1 | 0 | 0 |
![]() | 1-3 | 2 | 1 | 2 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 1-5 | 1 | 0 | 1 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 1 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 96 | 6.2 | 4 | 4 | |
![]() | 4 | 0.1 | 0 | 0 | |
![]() | 22 | 0.2 | 0 | 1 | |
![]() | 11 | 0.1 | 0 | 0 | |
![]() | 9 | 1 | 1 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 2-3 | 2 | 0 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 2-4 | 2 | 0 | 1 |
![]() | 1-4 | 0 | 0 | 3 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 2-4 | 1 | 1 | 1 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
Guardians vs. Diamondbacks Odds Comparison
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Guardians at Diamondbacks Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Guardians 1-2 | o4.5+108 | u4.5-138 |
![]() Diamondbacks 0-0 | o4.5+111 | u4.5-141 |