Dodgers vs. Padres Odds & Betting Predictions - May 21, 2026

Dodgers at Padres

12:40 am • SportsNet LA

Los Angeles Dodgers

San Diego Padres

pitcher		team	era	w-l
R.Vasquez			2.68	5-1
S.Ohtani			0.82	3-2

MatchupOpenSpreadTotalMoneyline
Dodgers 30-19	-1.5	-1.5-111	o7.5+100	-199
Padres 29-19	u7.5	+1.5-109	u7.5-120	+164

Thursday 12:40 a.m.

May 21, 2026

Petco ParkSan Diego

74°Fahrenheit

0%Rain

6Wind

LAD -1.5-110

LAD -185

0.46u

Ohtani in lineup - had been out when pitching. Split with F5 to -200

LAD -205 (F5)

0.51u

Split with full game to -220

R.Vasquez u16.5 Outs-130

1.3u

K.Tucker o1.5 Hits + Runs + RBIs-108

1.08u

LAD -0.5 (F5)-120

Join Discord for earlier access: https://discord.gg/HjKxYKdSUy This is the Ohtani window, with a 0.82 ERA and 50 strikeouts in 44 innings tied to a first-five bet. San Diego is not soft, but the Dodgers top order gets Ohtani, Betts, Freeman, Tucker and Smith before the game reaches the bullpen layer. I only need Los Angeles ahead by one after five, and that is the cleaner way to attack this matchup.

Under 0.5 (1st Inn)-113

1.13u

FD way off market

A.Pages o1.5 Total Bases+130

$1.00

Under 0.5 (1st Inn)-135

$1.35

#ACTION ✍️✍️ #Leadoff

F.Tatis o0.5 Singles-105

$1.05

#ACTION ✍️✍️ #SGP

A.Pages o0.5 HR+591

0.1u

X.Bogaerts o0.5 HR+820

0.1u

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No props found

MLB Public Betting

Padres are 4-1 in their last 5 games.
Padres are 5-0 in their last 5 games against the spread
Padres are 13-10 in their road games against the spread
The totals have gone OVER in 3 of Padres' last 5 games
The totals have gone OVER in 11 of Padres' 25 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Padres	28-20	15-10	13-10	13-12	15-8
Dodgers	24-25	10-15	14-10	24-25	N/A

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Padres	21-26-1	11-13-1	10-13	9-15-1	12-11
Dodgers	22-27	10-15	12-12	22-27	N/A

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Padres	29-19	14-11	15-8	15-10	14-9
Dodgers	30-19	15-10	15-9	30-19	N/A

date	opponent	score	spread	over/under	moneyline
May 20th	LAD	L 4-5	+1.5 W	O 8	LAD +144
May 19th	LAD	W 1-0	+1.5 W	U 7	SD +124
May 17th	@SEA	W 8-3	+1.5 W	O 7.5	SD +102
May 16th	@SEA	W 7-4	+1.5 W	O 7	SD +144
May 16th	@SEA	W 2-0	+1.5 W	U 7	SD +114

Blake Snell
SP
Blake Snell has been scratched Friday. Will Klein likely to start a bullpen game.
Out
Enrique Hernandez
1B
Hernandez is out with elbow
Out
Tommy Edman
2B
Edman is out with ankle
Out
Wyatt Mills
RP
Mills is out with elbow
Out
Bobby Miller
SP
Miller is out with shoulder
Out
Landon Knack
SP
Knack is out with undisclosed
Out
Gavin Stone
SP
Stone is out with shoulder
Out

Joe Musgrove
SP
Musgrove is out with elbow
Out
Will Wagner
3B
Wagner is out with oblique
Out

See more MLB Injuries

PITCHER		W-L	ERA	WHIP	K/9
RS.Ohtani, P		3-2	0.82	0.818	10.23

HITTERS	AVG	OBP	SLG	HR
1S.Ohtani, DH	.272	.399	.473	7
2M.Betts, SS	.172	.238	.397	4
3F.Freeman, 1B	.260	.342	.435	6
4K.Tucker, RF	.249	.347	.393	4
5A.Pages, CF	.294	.343	.506	10
6M.Muncy, 3B	.261	.363	.522	12
7W.Smith, C	.246	.318	.355	4
8T.Hernandez, LF	.263	.335	.406	5
9H.Kim, 2B	.270	.339	.350	1

PITCHER		W-L	ERA	WHIP	K/9
RR.Vasquez, P		5-1	2.68	1.113	8.05

HITTERS	AVG	OBP	SLG	HR
1F.Tatis, 2B	.237	.308	.277	0
2M.Andujar, DH	.299	.324	.522	5
3G.Sheets, 1B	.254	.340	.538	9
4M.Machado, 3B	.182	.277	.339	7
5X.Bogaerts, SS	.253	.324	.394	7
6J.Merrill, CF	.205	.275	.324	4
7N.Castellanos, RF	.189	.220	.337	3
8R.Laureano, LF	.213	.291	.368	5
9F.Fermin, C	.153	.237	.200	0