Astros vs. Orioles Odds & Betting Predictions - August 21, 2025

Astros at Orioles

11:15 pm • FOX

Houston Astros

69-58

2 - 0

Baltimore Orioles

59-67

MatchupOpenSpreadTotalMoneyline
Astros 69-58	-1.5	-1.5+163	o8.5-121	+100
Orioles 59-67	u8.5	+1.5-192	u8.5-101	-120

Thursday 11:15 p.m.

August 21, 2025

Oriole Park at Camden YardsBaltimore

HOU +108

#bobbyfades

HOU +108

#bobbyfades

BAL -118

1.25u

Under 0.5 (1st Inn)-110

1.1u

Under 9-120

0.6u

Under 9.5-166

0.5u

Under 9-117

0.59u

Action Instagram channel best bet, going to tail it

BAL -115

Y.Diaz o0.5 HR+875

0.5u

J.Altuve o0.5 HR+900

0.5u

C.Walker o0.5 HR+650

0.5u

Under 9-108

0.54u

Bet to -125 or 8.5 (-105)

Astros vs Orioles: +120 SGP for Thursday
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Aug 21, 2025 UTC
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No props found

MLB Public Betting

Orioles are 4-1 in their last 5 games.
Orioles are 5-0 in their last 5 games against the spread
Orioles are 33-33 in their road games against the spread
The totals have gone OVER in 3 of Orioles' last 5 games
The totals have gone OVER in 30 of Orioles' 60 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Orioles	60-66	27-33	33-33	20-36	38-30
Astros	63-64	30-35	33-29	34-51	29-11

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Orioles	53-69-4	30-28-2	23-41-2	28-26-2	24-42-2
Astros	58-63-6	29-35-1	29-28-5	40-43-2	16-20-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Orioles	59-67	30-30	29-37	25-31	32-36
Astros	69-58	38-27	31-31	46-39	23-17

date	opponent	score	spread	over/under	moneyline
Aug 19th	@BOS	W 4-3	+1.5 W	U 9.5	BAL +125
Aug 18th	@BOS	W 6-3	-1.5 W	O 8	BAL +105
Aug 17th	@HOU	W 12-0	-1.5 W	O 8.5	BAL -101
Aug 16th	@HOU	L 4-5	+1.5 W	O 8.5	HOU +118
Aug 16th	@HOU	W 7-0	+1.5 W	U 7.5	BAL +184

Jake Meyers
CF
Meyers is out with calf
Out
Luis Garcia
SP
Garcia is out with elbow
Out
Pedro Leon
RF
Leon is out with knee
Out
J.P. France
SP
France is out with shoulder
Out
Hayden Wesneski
RP
Wesneski is out with elbow
Out

Albert Suarez
RP
Suarez is out with shoulder
Out
Jorge Mateo
SS
Mateo is out with hamstring
Out
Kyle Bradish
SP
Bradish is out with elbow
Out
Grayson Rodriguez
SP
Rodriguez is out with elbow
Out
Tyler Wells
SP
Wells is out with elbow
Out

See more MLB Injuries

PITCHER		PC	IP	K	ER
RJ.Alexander, P		10	0.1	0	0

HITTERS	H-AB	R	HR	RBI
1J.Pena, SS	0-1	0	0	0
2C.Correa, 3B	1-1	1	0	0
3J.Altuve, 2B	0-1	0	0	0
4C.Walker, 1B	1-1	1	1	2
5J.Sanchez, RF	1-1	0	0	0
6Y.Diaz, DH	0-1	0	0	0
7V.Caratini, C	-
8M.Dubon, LF	-
9J.Melton, CF	-

PITCHER		PC	IP	K	ER
RB.Young, P		18	1	0	2

HITTERS	H-AB	R	HR	RBI
1J.Holliday, 2B	1-1	0	0	0
2J.Jackson, 3B	0-1	0	0	0
3G.Henderson, SS	1-1	0	0	0
4R.Mountcastle, DH	-
5C.Cowser, CF	-
6S.Basallo, C	-
7C.Mayo, 1B	-
8D.Beavers, RF	-
9D.Carlson, LF	-