Astros vs. Blue Jays Odds & Betting Predictions - June 22, 2026

Astros at Blue Jays

11:07 pm • SNET
2 - 4
Starting Pitchers
pitcherteameraw-l
Dylan Cease logoD.CeaseToronto Blue Jays logo2.754-3
Hunter Brown logoH.BrownHouston Astros logo1.401-0

Astros at Blue Jays Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
37-43
+1.5
+1.5-198
o7-118
+112
Blue Jays
39-39
u7.5
-1.5+164
u7-106
-135
location pinMonday 11:07 p.m.
June 22, 2026
Rogers CentreToronto
Astros vs. Blue Jays Expert Picks
Player Prop Savant
Player Prop Savant
Last 30d: 100-74-0 (+20.9u)
TOR -1.5 (Live)+260
2.6u
TOR +1.5 (Live)-105
1u
Under 9.5 (Live)-125
1u
The Degenerates
The Degenerates
Last 30d: 50-68-4 (-22.9u)
HOU +108
1u
Sean Koerner🔮
Sean Koerner🔮
Last 30d: 58-48-2 (+9.7u)
H.Brown u5.5 Ks-108
0.5u
Brown owns a ridiculous 38% K rate through his first three starts, but my expected K model has him much closer to the 27-28% range we’d normally expect. He’s benefited from a pretty favorable schedule so far with all 3 starts coming at home and a nearly perfect 50/50 split of righties and lefties. That’s important because Brown has fairly sharp reverse splits and actually strikes out left-handed hitters at a higher rate. Toronto is sending six righties to the plate tonight, which subtly dings his strikeout expectation. The biggest reason I’m fading him, though, is how he’s gotten there. Brown has benefited enormously from opponents simply refusing to swing at strikes. That’s arguably the easiest path to strikeouts because every taken pitch in the zone is automatically a strike unless the umpire misses the call. Once hitters start swinging at those pitches, they at least introduce the possibility of contact, foul balls, or extending the plate appearance. Not only are the Blue Jays one of the tougher teams in baseball to strike out, they also swing at pitches in the zone at the 4th-highest rate in the league. They’re almost perfectly built to challenge the area where Brown has been running hottest. He’s always been above average at freezing hitters, but not nearly to the extent we’ve seen through three starts. I’m projecting him closer to -150 to stay under 5.5 strikeouts.
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 50-87-11 (-12.8u)
D.Cease o6.5 Ks-124
0.2u
@cowhitchurch ⭐️ https://myaction.app/y7JaOEYub4b
💰🦡 Jake
💰🦡 Jake
Last 30d: 57-81-2 (-17.3u)
Under 3.5 (F5)+100
1u
Frank Ammirante
Frank Ammirante
Last 30d: 309-266-11 (+45.8u)
H.Brown o5.5 Ks-120
1.2u
D.Cease o6.5 Ks-143
1u
Under 7.5-123
1u
Brian Bitler
Brian Bitler
Last 30d: 87-90-1 (+19.1u)
HOU +108
3u
Picks Office
Picks Office
Last 30d: 130-135-12 (-14.6u)
TOR -120
0.83u
Matt Trollo
Matt Trollo
Last 30d: 72-77-9 (-6.1u)
HOU +110
0.5u
(B365) Cease being listed and it seems like lines are based on him instead of Bieber. Brown projects a bit better than Bieber. HOU proj. LU 113/118 wRC+ v RHP/L30, TOR 104/105. Defenses comparable. HOU pen estimators (FIP/xFIP/SIERA) avg 0.82 runs better L30 days. If it's Cease instead of Bieber, this is probably a break even line anyway.

Astros vs. Blue Jays Previews & Analysis

  • Astros vs Blue Jays: Can the Jays Get to Brown? article feature image

    Astros vs Blue Jays: Can the Jays Get to Brown?

    Jon Anderson
    Jun 22, 2026 UTC
  • The Leadoff: Anderson's MLB Breakdown and Bets for Monday article feature image

    The Leadoff: Anderson's MLB Breakdown and Bets for Monday

    Jon Anderson
    Jun 22, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Astros vs. Blue Jays Public Betting Percentages

Away Logo

Astros

Public

43%

Bets%

57%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Blue Jays
38-4020-2018-2021-2016-20
Astros
37-4319-2218-218-1828-24

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Blue Jays
38-37-321-18-117-19-221-18-216-19-1
Astros
41-35-424-16-117-19-315-1125-23-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Blue Jays
39-3922-1817-2124-1714-22
Astros
37-4320-2117-2211-1525-27

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jun 20th@CHCW 8-6+1.5 WO 9TOR +119
Jun 19th@CHCL 2-16+1.5 LO 7CHC +105
Jun 18th@BOSW 4-3+1.5 WU 9.5TOR +120
Jun 17th@BOSW 3-0-1.5 WU 10TOR -105
Jun 16th@BOSW 6-1-1.5 WU 7.5TOR -120

Blue Jays vs. Astros Injury Updates

Blue Jays Injuries

  • Jose Berrios
    SP

    Berrios is out with elbow

    Out

  • Anthony Santander
    RF

    Santander is out with shoulder

    Out

  • Bowden Francis
    SP

    Francis is out with shoulder

    Out

  • Addison Barger
    RF

    Addison Barger (elbow) scratched Sunday.

    Out

Astros Injuries

  • Lance McCullers
    SP

    Lance McCullers Jr. has been scratched Tuesday. Jason Alexander will start.

    Out

Astros vs. Blue Jays Box Score
Astros Player Stats
Projected
PITCHERPCIPKER
Hunter Brown logoRH.Brown, P85341
AJ Blubaugh logoRA.Blubaugh, P38211
Enyel De Los Santos logoRE.De Los Santos, P191.121
Bryan King logoLB.King, P110.210
Logan VanWey logoRL. VanWey, P16101
HITTERSH-ABRHRRBI
Jeremy Pena logo1J.Pena, SS1-2100
Brice Matthews logo1B.Matthews, PH1-2000
Brice Matthews logo1B.Matthews, 3B1-2000
Yordan Alvarez logo2Y.Alvarez, LF1-2100
Christian Walker logo3C.Walker, 1B0-3000
Isaac Paredes logo4I.Paredes, DH1-3001
Jose Altuve logo5J.Altuve, 2B1-3001
Yainer Diaz logo6Y.Diaz, C0-3000
Joey Loperfido logo7J.Loperfido, RF0-4000
Jake Meyers logo8J.Meyers, CF0-3000
Taylor Trammell logo8T.Trammell, PH0-1000
Raynel Delgado logo9R.Delgado, 3B0-3000
Raynel Delgado logo9R.Delgado, SS0-3000
Blue Jays Player Stats
Projected
PITCHERPCIPKER
Dylan Cease logoRD.Cease, P1105.282
Braydon Fisher logoRB.Fisher, P61.100
Tyler Rogers logoRT.Rogers, P19100
Louis Varland logoRL.Varland, P12110
HITTERSH-ABRHRRBI
George Springer logo1G.Springer, DH2-4100
Nathan Lukes logo2N.Lukes, RF1-4000
Vladimir Guerrero logo3V.Guerrero, 1B2-4001
Alejandro Kirk logo4A.Kirk, C1-4001
Daulton Varsho logo5D.Varsho, CF1-4100
Kazuma Okamoto logo6K.Okamoto, 3B2-3111
Jesus Sanchez logo7J.Sanchez, LF0-1000
Myles Straw logo7M.Straw, PH0-0001
Myles Straw logo7M.Straw, LF0-0001
Ernie Clement logo8E.Clement, 2B1-3000
Andres Gimenez logo9A.Gimenez, SS1-3100

Astros vs. Blue Jays Odds Comparison

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Astros at Blue Jays Team Totals

MatchupOverUnder
Astros
37-43
N/A
N/A
Blue Jays
39-39
N/A
N/A