Houston vs. Louisiana Odds, Picks, Predictions: Independence Bowl Landing Big College Football Bets on Friday

PJ Walsh

Dec 23, 2022, 12:56 PM EST

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Photo by James Gilbert/Getty Images. Pictured: Head coach Michael Desormeaux of the Louisiana-Lafayette Ragin Cajuns

Friday's college football slate gets underway with Houston taking on Louisiana in the 2022 Independence Bowl.
Live college football odds show Houston as a 7-point spread favorite against Louisiana, with the over/under at 56.5.
Using our college football picks and predictions, we detail how experts are betting Houston vs. Louisiana in Friday's Independence Bowl.

Houston vs. Louisiana Odds

Houston Odds	-7
Louisiana Odds	+7
Over/Under	56.5
Date	Friday, Dec. 23
Time	3 p.m. ET
Channel	ESPN

*Odds as of Friday morning

Friday's college football bowl schedule is two games deep, starting with Houston vs. Louisiana in the Independence Bowl and followed by Wake Forest vs. Missouri in the Gasparilla Bowl.

According to the latest college football odds, the Houston vs. Louisiana spread hasn't moved all that much since opening. However, the Action Network's picks and predictions data is showing that experts are lining up on one side of the Independence Bowl.

With this in mind, let's examine college football expert picks for Houston vs. Louisiana in Friday's Independence Bowl.