Orioles vs. White Sox Odds & Betting Predictions - September 15, 2025

Orioles at White Sox

11:40 pm • CHSN
4 - 1
Starting Pitchers
pitcherteameraw-l
Tyler Gilbert logoT.GilbertChicago White Sox logo4.084-1
Kyle Bradish logoK.BradishBaltimore Orioles logo2.461-1

Orioles at White Sox Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Orioles
70-80
-1.5
-1.5+118
o8-105
-139
White Sox
57-94
u8
+1.5-143
u8-115
+117
location pinMonday 11:40 p.m.
September 15, 2025
Rate FieldChicago
Orioles vs. White Sox Expert Picks
Grant Neiffer
Grant Neiffer
Last 30d: 49-130-9 (+30.7u)
T.O'Neill o0.5 HR+460
0.25u
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 49-67-4 (-4.9u)
G.Henderson o2.5 Hits + Runs + RBIs+155
1u
Kyle Murray
Kyle Murray
Last 30d: 47-52-4 (+0.7u)
G.Henderson o2.5 Hits + Runs + RBIs+155
1u
Brian Bitler
Brian Bitler
Last 30d: 98-88-0 (+19.6u)
CWS +125
3u

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Prop Odds Comparison

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Line Movement Tracker

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Orioles vs. White Sox Public Betting Percentages

Away Logo

Orioles

Public

78%

Bets%

22%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
White Sox
88-6344-3244-310-287-61
Orioles
73-7734-4039-3723-4048-37

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
White Sox
70-74-740-31-530-43-20-269-72-7
Orioles
62-84-433-39-229-45-231-30-230-53-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
White Sox
57-9432-4425-501-155-93
Orioles
70-8036-3834-4230-3338-47

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 14th@CLEL 2-3+1.5 WU 8CLE +130
Sep 13th@CLEL 1-3+1.5 LU 7.5CLE +146
Sep 12th@CLEL 0-4+1.5 LU 7.5CLE +119
Sep 11thTBW 5-1+1.5 WU 7.5CWS +110
Sep 10thTBW 6-5+1.5 WO 8.5CWS +111

White Sox vs. Orioles Injury Updates

White Sox Injuries

  • Ky Bush
    SP

    Bush is out with elbow

    Out

  • Drew Thorpe
    SP

    Thorpe is out with elbow

    Out

Orioles Injuries

  • Grayson Rodriguez
    SP

    Rodriguez is out with elbow

    Out

Orioles vs. White Sox Box Score
Orioles Player Stats
Projected
PITCHERPCIPKER
Kyle Bradish logoRK.Bradish, P88591
Kade Strowd logoRK.Strowd, P16120
Dietrich Enns logoLD.Enns, P32340
HITTERSH-ABRHRRBI
Jackson Holliday logo1J.Holliday, 2B2-4000
Jeremiah Jackson logo2J.Jackson, 3B1-4001
Emmanuel Rivera logo2E.Rivera, 3B0-0000
Gunnar Henderson logo3G.Henderson, SS0-4000
Tyler O'Neill logo4T.O'Neill, RF1-4000
Ryan Mountcastle logo5R.Mountcastle, 1B1-4000
Dylan Beavers logo6D.Beavers, LF0-4000
Coby Mayo logo7C.Mayo, DH0-1100
Samuel Basallo logo8S.Basallo, C1-3200
Colton Cowser logo9C.Cowser, CF1-4113
White Sox Player Stats
Projected
PITCHERPCIPKER
Tyler Gilbert logoLT.Gilbert, P10110
Sean Burke logoRS.Burke, P89441
Steven Wilson logoRS.Wilson, P160.211
Tyler Alexander logoLT.Alexander, P230.102
Mike Vasil logoRM.Vasil, P49320
HITTERSH-ABRHRRBI
Mike Tauchman logo1M.Tauchman, RF0-2100
Kyle Teel logo2K.Teel, C0-4000
Lenyn Sosa logo3L.Sosa, 1B0-4000
Colson Montgomery logo4C.Montgomery, SS1-3000
Curtis Mead logo5C.Mead, 3B1-4001
Andrew Benintendi logo6A.Benintendi, LF0-2000
Miguel Vargas logo6M.Vargas, PH0-1000
Edgar Quero logo7E.Quero, DH0-3000
Chase Meidroth logo8C.Meidroth, 2B1-3000
Dominic Fletcher logo9D.Fletcher, CF1-2000
Michael A. Taylor logo9M.Taylor, PH0-1000
Michael A. Taylor logo9M.Taylor, CF0-1000

Orioles vs. White Sox Odds Comparison

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Orioles at White Sox Team Totals

MatchupOverUnder
Orioles
70-80
o4.5+106
N/A
White Sox
57-94
o3.5-110
u3.5-117