White Sox vs. Guardians Odds & Betting Predictions - September 14, 2025

White Sox at Guardians

5:40 pm • CHSN

Chicago White Sox

2

2 - 3

Cleveland Guardians

3

pitcher		team	era	w-l
S.Cecconi			4.30	7-7
Y.Gomez			2.70	1-1

MatchupOpenSpreadTotalMoneyline
White Sox 0-0	+1.5	+1.5-164	o8+100	+130
Guardians 1-2	u8.5	-1.5+137	u8-118	-162

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Sunday 5:40 p.m.

September 14, 2025

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MLB Public Betting

Guardians are 3-2 in their last 5 games.
Guardians are 1-4 in their last 5 games against the spread
Guardians are 47-34 in their road games against the spread
The totals have gone OVER in 2 of Guardians' last 5 games
The totals have gone OVER in 37 of Guardians' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	86-76	39-42	47-34	33-36	51-38
White Sox	94-68	47-34	47-34	0-2	92-66

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	69-87-6	37-41-3	32-46-3	34-34-1	34-50-5
White Sox	75-80-7	42-34-5	33-46-2	0-2	73-78-7

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	88-74	45-36	43-38	44-25	43-46
White Sox	60-102	33-48	27-54	1-1	58-100

date	opponent	score	spread	over/under	moneyline
Sep 13th	CWS	W 3-1	-1.5 W	U 7.5	CLE -171
Sep 12th	CWS	W 4-0	-1.5 W	U 7.5	CLE -142
Sep 11th	KC	W 3-2	-	-	CLE -144
Sep 10th	KC	L 3-4	+1.5 W	U 8	KC -110
Sep 9th	KC	W 2-0	+1.5 W	U 7.5	CLE -110

Ky Bush
SP
Bush is out with elbow
Out
Drew Thorpe
SP
Thorpe is out with elbow
Out

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PITCHER		PC	IP	K	ER
RY.Gomez, P		77	5	4	2
LB.Eisert, P		25	1.2	1	1
LF.Ellard, P		11	0.1	0	0
RW.Gonzalez, P		19	1	1	0

HITTERS	H-AB	R	HR	RBI
1M.Tauchman, RF	0-4	0	0	0
2K.Teel, C	1-4	0	0	0
3L.Sosa, 1B	1-4	1	0	0
4C.Montgomery, SS	0-3	0	0	0
5M.Vargas, 3B	2-4	0	0	1
6A.Benintendi, DH	0-4	0	0	0
7W.Robertson, LF	0-3	0	0	0
8C.Meidroth, 2B	1-3	1	1	1
9D.Fletcher, CF	0-3	0	0	0

PITCHER		PC	IP	K	ER
RS.Cecconi, P		93	5.2	4	2
LT.Herrin, P		5	0.1	1	0
RM.Festa, P		14	1	3	0
RH.Gaddis, P		16	1	1	0
RC.Smith, P		12	1	2	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	0-3	1	0	0
2N.Jones, CF	0-2	0	0	0
2A.Martinez, PH	1-2	0	0	0
2A.Martinez, CF	1-2	0	0	0
3J.Ramirez, DH	1-3	1	0	0
4K.Manzardo, 1B	0-4	0	0	0
4J.Noel, RF	0-0	0	0	0
5B.Naylor, C	2-3	1	1	3
6G.Arias, SS	0-4	0	0	0
7D.Schneemann, 3B	1-3	0	0	0
8C.Kayfus, RF	1-3	0	0	0
8C.Kayfus, 1B	1-3	0	0	0
9B.Rocchio, 2B	0-2	0	0	0

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MatchupOverUnder
White Sox 0-0	o3.5-105	u3.5-122
Guardians 1-2	o4.5+113	u4.5-144