Nationals vs. Guardians Odds & Betting Predictions - May 27, 2026

Nationals at Guardians

5:10 pm • CLEG
1 - 3

Nationals at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Nationals
29-27
+1.5
+1.5-148
o7.5-119
+151
Guardians
32-25
u8.5
-1.5+117
u7.5-102
-180
location pinWednesday 5:10 p.m.
May 27, 2026
Progressive FieldCleveland
Nationals vs. Guardians Expert Picks
Player Prop Savant
Player Prop Savant
Last 30d: 147-133-2 (+7.5u)
CLE +115 (Live)
0.87u
Under 8.5 (Live)-130
1.3u
Kyle Murray
Kyle Murray
Last 30d: 16-40-3 (-9.4u)
G.Williams u6.5 Ks-103
1.03u
Sean Koerner🔮
Sean Koerner🔮
Last 30d: 45-46-2 (-0.1u)
G.Williams u6.5 Ks-110
0.55u
Proj closer to -140
The Degenerates
The Degenerates
Last 30d: 75-83-7 (-11.7u)
CLE -1.5+116
1u
Markus Markets
Markus Markets
Last 30d: 46-38-0 (+3.1u)
G.Williams u18.5 Outs-140
1.4u
Frank Ammirante
Frank Ammirante
Last 30d: 216-250-11 (-22.3u)
Over 7.5-116
1.16u
Doug Ziefel
Doug Ziefel
Last 30d: 189-148-2 (+18.2u)
Under 8-117
0.59u
Ryan Minion
Ryan Minion
Last 30d: 357-383-15 (+8.4u)
J.Ramirez o2.5 Hits + Runs + RBIs+120
$1.00
CLE -178
$1.78
#ACTION ✍️✍️ #Leadoff
J.Ramirez To Record 2+ Stolen Bases Yes+2000
$0.30
#ACTION ✍️✍️ #Leadoff 🪜
Adam Kaufman
Adam Kaufman
Last 30d: 53-52-0 (-3.5u)
WSH +158
1u
Sean Zerillo
Sean Zerillo
Last 30d: 175-145-11 (+6.5u)
Under 8-110
0.55u
Bet to 7.5 (+100)

Nationals vs. Guardians Previews & Analysis

  • The Leadoff: Minion's MLB Breakdown and Bets for Wednesday article feature image

    The Leadoff: Minion's MLB Breakdown and Bets for Wednesday

    Ryan Minion
    May 27, 2026 UTC
  • Minion's Pick for Nationals-Guardians article feature image

    Minion's Pick for Nationals-Guardians

    Ryan Minion
    May 27, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Nationals vs. Guardians Public Betting Percentages

Away Logo

Nationals

Public

27%

Bets%

73%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
31-2616-1115-1517-1614-10
Nationals
35-2112-1423-71-134-20

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
28-2914-1314-1617-1611-13
Nationals
35-18-317-7-218-11-12-033-18-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
32-2515-1217-1319-1413-11
Nationals
29-2710-1619-111-128-26

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 26thWSHL 3-6-1.5 LO 7.5WSH -133
May 25thWSHL 2-10-1.5 LO 8.5WSH -174
May 24th@PHIW 3-1-1.5 WU 7CLE -115
May 23rd@PHIL 0-3+1.5 LU 7PHI +145
May 22nd@PHIW 1-0+1.5 WU 6.5CLE +154

Guardians vs. Nationals Injury Updates

Guardians Injuries

    Nationals Injuries

    • Trevor Williams
      SP

      Williams is out with elbow

      Out

    • Josiah Gray
      SP

      Josiah Gray (elbow) scratched Tuesday.

      Out

    • DJ Herz
      SP

      Herz is out with elbow

      Out

    Nationals vs. Guardians Box Score
    Nationals Player Stats
    Projected
    PITCHERPCIPKER
    PJ Poulin logoLP.Poulin, P13110
    Miles Mikolas logoRM.Mikolas, P603.210
    Richard Lovelady logoLR.Lovelady, P120.101
    Orlando Ribalta logoRO.Ribalta, P19100
    HITTERSH-ABRHRRBI
    James Wood logo1J.Wood, RF1-2100
    Luis Garcia logo2L.Garcia, 1B0-3000
    Curtis Mead logo3C.Mead, 3B0-3000
    C.J. Abrams logo4C.Abrams, SS1-2001
    Daylen Lile logo5D.Lile, LF0-3000
    Jose Tena logo6J.Tena, DH0-3000
    Jorbit Vivas logo7J.Vivas, 2B0-2000
    Drew Millas logo8D.Millas, C1-2000
    Jacob Young logo9J.Young, CF0-2000
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Gavin Williams logoRG.Williams, P876.241
    HITTERSH-ABRHRRBI
    Travis Bazzana logo1T.Bazzana, 2B2-4100
    Jose Ramirez logo2J.Ramirez, DH0-2001
    Chase DeLauter logo3C.DeLauter, RF1-3101
    Kyle Manzardo logo4K.Manzardo, 1B1-3000
    Angel Martinez logo5A.Martinez, LF2-3001
    Daniel Schneemann logo6D.Schneemann, 3B1-2000
    Steven Kwan logo7S.Kwan, CF1-3000
    Austin Hedges logo8A.Hedges, C0-3100
    Brayan Rocchio logo9B.Rocchio, SS1-3000

    Nationals vs. Guardians Odds Comparison

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    Nationals at Guardians Team Totals

    MatchupOverUnder
    Nationals
    29-27
    N/A
    N/A
    Guardians
    32-25
    N/A
    N/A