Guardians vs. Astros Odds & Betting Predictions - June 21, 2026

Guardians at Astros

6:10 pm • CLEG

Cleveland Guardians

41-37

1 - 2

Houston Astros

37-42

pitcher		team	era	w-l
K.Teng			4.31	3-6
S.Cecconi			4.60	3-5

MatchupOpenSpreadTotalMoneyline
Guardians 41-37	+1.5	+1.5-188	o8.5-105	+112
Astros 37-42	u8.5	-1.5+157	u8.5-111	-133

Sunday 6:10 p.m.

June 21, 2026

Daikin ParkHouston

HOU o0.5+160

1.6u

HOU o4.5+100

Under 8.5-104

0.5u

Bet to -115

Under 8.5-104

0.5u

Need a Kai-Wei Teng masterclass 🙏

Under 8.5+100

1.5u

J.Altuve o1.5 Hits + Runs + RBIs+104

C.Walker o1.5 Hits + Runs + RBIs-120

$1.20

#ACTION ✍️✍️ #MLBLeadoff

CLE +116

T.Bazzana o0.5 HR+741

0.1u

T.Bazzana o1.5 Total Bases+141

0.71u

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No props found

MLB Public Betting

Astros are 4-1 in their last 5 games.
Astros are 3-2 in their last 5 games against the spread
Astros are 18-20 in their road games against the spread
The totals have gone OVER in 2 of Astros' last 5 games
The totals have gone OVER in 24 of Astros' 41 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Astros	37-42	19-22	18-20	8-18	28-23
Guardians	42-36	19-17	23-19	18-23	24-13

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Astros	41-34-4	24-16-1	17-18-3	15-11	25-22-4
Guardians	38-40	18-18	20-22	21-20	17-20

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Astros	37-42	20-21	17-21	11-15	25-26
Guardians	41-37	19-17	22-20	22-19	19-18

date	opponent	score	spread	over/under	moneyline
Jun 20th	CLE	L 1-8	-1.5 L	O 8.5	CLE -156
Jun 20th	CLE	W 9-3	-1.5 W	O 8.5	HOU -125
Jun 17th	DET	W 4-2	+1.5 W	U 8.5	HOU -110
Jun 17th	DET	W 4-2	-1.5 W	U 8.5	HOU -175
Jun 16th	DET	L 3-9	-1.5 L	O 9	DET -125

Lance McCullers
SP
Lance McCullers Jr. has been scratched Tuesday. Jason Alexander will start.
Out

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PITCHER	PC	IP	K	ER
RS.Cecconi, P	79	6	1	2
RC.Holderman, P	9	1	1	0
RH.Gaddis, P	14	1	1	0

HITTERS	H-AB	R	RBI
1T.Bazzana, DH	1-4	0	1
2K.Manzardo, 1B	1-4	0	0
3B.Rocchio, SS	1-4	0	0
4G.Arias, 3B	0-4	0	0
5D.Schneemann, 2B	0-4	0	0
6K.Watson, RF	0-2	0	0
6D.Fry, PH	0-2	0	0
6D.Fry, LF	0-2	0	0
7S.Kwan, LF	0-2	0	0
7S.Fairchild, PH	0-0	0	0
7S.Fairchild, RF	0-0	0	0
8P.Bailey, C	0-1	0	0
8R.Hoskins, PH	0-1	0	0
8A.Hedges, C	0-0	0	0
9P.Halpin, CF	1-3	1	0

PITCHER	PC	IP	K	ER
RK.Teng, P	83	6	4	1
LS.Okert, P	21	1	3	0
LB.King, P	11	1	1	0
LJ.Hader, P	9	1	2	0

HITTERS	H-AB	R	HR	RBI
1J.Pena, SS	1-4	0	0	0
2Y.Alvarez, LF	1-2	2	1	1
2B.Matthews, LF	0-0	0	0	0
3C.Walker, 1B	1-4	0	0	0
4I.Paredes, 3B	3-4	0	0	1
5J.Altuve, DH	0-4	0	0	0
6J.Loperfido, CF	0-3	0	0	0
6J.Meyers, CF	0-0	0	0	0
7C.Smith, RF	0-3	0	0	0
8R.Delgado, 2B	1-3	0	0	0
9C.Vazquez, C	0-2	0	0	0