Guardians vs. Astros Odds & Betting Predictions - June 20, 2026
Guardians at Astros
11:15 pm • FOXStarting Pitchers
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Guardians at Astros Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Guardians 40-36 | +1.5 | +1.5-177 | o8.5-105 | +120 |
Astros 36-41 | u8.5 | -1.5+145 | u8.5-115 | -142 |

Daikin ParkHouston
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Guardians vs. Astros Expert Picks

Sean Zerillo
Last 30d: 145-124-9 (+0.5u)
HOU -135
0.68u
Bet to -150
Guardians vs. Astros Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Guardians vs. Astros Public Betting Percentages
Betting Trends
- Astros are 3-2 in their last 5 games.
- Astros are 3-2 in their last 5 games against the spread
- Astros are 18-20 in their road games against the spread
- The totals have gone OVER in 2 of Astros' last 5 games
- The totals have gone OVER in 23 of Astros' 39 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Astros Injury Updates

Guardians Injuries

Astros Injuries
- Lance McCullersSP
Lance McCullers Jr. has been scratched Tuesday. Jason Alexander will start.
Out
Guardians vs. Astros Odds Comparison
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Guardians at Astros Team Totals
MatchupOverUnder | ||
|---|---|---|
Guardians 40-36 | N/A | N/A |
Astros 36-41 | N/A | N/A |



