Astros vs. Rays Odds & Betting Predictions - May 21, 2025

Astros at Rays

5:10 pm • FDSSUN
4 - 8
Starting Pitchers
pitcherteameraw-l
Taj Bradley logoT.BradleyTampa Bay Rays logo4.616-6
Hunter Brown logoH.BrownHouston Astros logo2.4312-9

Astros at Rays Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
15-23
-1.5
-1.5+107
o8.5-112
-168
Rays
25-12
u9
+1.5-122
u8.5-110
+142
location pinWednesday 5:10 p.m.
May 21, 2025
George M. Steinbrenner FieldTampa
Astros vs. Rays Expert Picks
Charlie Wright
Charlie Wright
Last 30d: 0-0-0 (+0.0u)
T.Bradley u17.5 Outs+120
1u
YBK Picks.com
Last 30d: 29-24-1 (+8.2u)
HOU -1-130
2u
The Degenerates
The Degenerates
Last 30d: 98-104-11 (-9.5u)
HOU -148
1.48u
Collin Whitchurch
Collin Whitchurch
Last 30d: 39-81-3 (-7.6u)
I.Paredes To Hit 1+ Home Runs Yes+500
1.25u
C.Walker To Hit 1+ Home Runs Yes+320
0.25u
💰🦡 Jake
💰🦡 Jake
Last 30d: 69-83-4 (-3.0u)
HOU -0.5 (F5)-105
1.05u
The Propfessor
The Propfessor
Last 30d: 46-57-0 (+6.2u)
T.Bradley o1.5 BB-117
1u
Austin Pendergrass
Austin Pendergrass
Last 30d: 42-35-0 (-2.7u)
HOU -158 (F5)
1u
Doug Ziefel
Doug Ziefel
Last 30d: 229-228-9 (+0.2u)
HOU -0.5 (F5)-110
0.55u
CeeJ Sports
CeeJ Sports
Last 30d: 0-0-0 (+0.0u)
H.Brown o6.5 Ks-106
1.06u
Took this on NoVig, but Action doesn't have them as a book to track yet.
Cam Is Money
Cam Is Money
Last 30d: 119-155-3 (-33.3u)
I.Paredes o1.5 Hits + Runs + RBIs-120
0.83u
Billy Ward
Billy Ward
Last 30d: 36-40-3 (-3.6u)
Under 0.5 (1st Inn)-120
1.2u
Ryan Minion
Ryan Minion
Last 30d: 326-386-13 (-6.3u)
HOU -140 (F5)
$1.40
Picks Office
Picks Office
Last 30d: 189-175-11 (+2.6u)
HOU -135
1u
Rays stuck in a home rut – 3-13 in last 16 at George M. Steinbrenner Field. Taj Bradley shaky – 5 ER in 4 IP last start, 9.95 ERA in 3 career outings vs Astros. Bullpen collapse: 5.86 ERA last 3 games. Houston’s offense clicking – Altuve, Meyers heating up. Hunter Brown = lights out. 6-2, 1.43 ERA, 0.829 WHIP in ‘25. 2-0 vs Rays, 1.06 ERA career. 27.0 bullpen innings last 3 games, 1.00 ERA, 0.67 WHIP. Brown last 3 starts: 1.83 ERA, 0.813 WHIP. No signs of slowing. Rays can’t solve him. Offense won’t save them. Bradley has 5 HR allowed in 12.2 IP vs HOU. Rays scoring just 3.79 runs/game at home (24th in MLB). Astros had won 5 of 7 before Tuesday. Multiple analysts backing Houston. Dimers model leans Astros (55%). Too many signs to ignore.
Doug Ziefel
Doug Ziefel
Last 30d: 229-228-9 (+0.2u)
T.Bradley o2.5 Earned Runs+105
0.48u
Brian Bitler
Brian Bitler
Last 30d: 95-86-0 (+47.2u)
TB +122
3.66u
Doug Ziefel
Doug Ziefel
Last 30d: 229-228-9 (+0.2u)
H.Brown o7.5 Ks+145
0.34u
Austin Pendergrass
Austin Pendergrass
Last 30d: 42-35-0 (-2.7u)
H.Brown o6.5 Ks-132
0.25u
Sean Zerillo
Sean Zerillo
Last 30d: 164-151-17 (-2.0u)
TB +123
0.62u
Bet to +108
Brandon Kravitz
Brandon Kravitz
Last 30d: 57-99-3 (-39.0u)
Under 8.5+105
0.5u
Matt Trollo
Matt Trollo
Last 30d: 61-56-5 (+4.6u)
T.Bradley u4.5 Ks+130
0.5u
Lower K% vs RHBs career (23.4%) and this year (18%). 5.25 Bot ERA, 89 Pitching+. 5 of F6 in proj HOU LU all below 19 K% v RHP since last year - hitter friendly park and weather

Astros vs. Rays Previews & Analysis

  • Wright's Astros vs Rays Pitcher Prop For Wednesday Afternoon article feature image

    Wright's Astros vs Rays Pitcher Prop For Wednesday Afternoon

    Charlie Wright
    May 21, 2025 UTC
  • 4 MLB NRFI & YRFI Picks for Wednesday article feature image

    4 MLB NRFI & YRFI Picks for Wednesday

    Billy Ward
    May 21, 2025 UTC
  • 3 MLB Player Props for Wednesday article feature image

    3 MLB Player Props for Wednesday

    Doug Ziefel
    May 21, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Astros vs. Rays Public Betting Percentages

Away Logo

Astros

Public

85%

Bets%

15%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Rays
24-1313-511-814-710-6
Astros
15-238-117-124-1111-11

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Rays
17-18-26-11-111-7-19-10-28-8
Astros
24-12-214-510-7-29-614-6-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Rays
25-1214-411-815-610-6
Astros
15-239-106-135-1010-12

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 20thHOUW 3-2-1.5 LU 9TB -135
May 19thHOUL 3-4-1.5 LU 9HOU -144
May 18th@MIAL 1-5-1.5 LU 9MIA -164
May 17th@MIAW 4-0-1.5 WU 8TB -147
May 16th@MIAL 4-9-1.5 LO 8.5MIA -126

Rays vs. Astros Injury Updates

Rays Injuries

  • Gavin Lux
    LF

    Lux is out with shoulder

    Out

  • Michael Grove
    RP

    Grove is out with shoulder

    Out

Astros Injuries

    Astros vs. Rays Box Score
    Astros Player Stats
    Projected
    PITCHERPCIPKER
    Hunter Brown logoRH.Brown, P91545
    Bennett Sousa logoLB.Sousa, P25230
    Forrest Whitley logoRF.Whitley, P330.213
    Steven Okert logoLS.Okert, P60.100
    HITTERSH-ABRHRRBI
    Jeremy Pena logo1J.Pena, SS0-3100
    Isaac Paredes logo2I.Paredes, 3B2-4223
    Jose Altuve logo3J.Altuve, DH0-3000
    Yainer Diaz logo4Y.Diaz, C1-4000
    Christian Walker logo5C.Walker, 1B1-4000
    Jake Meyers logo6J.Meyers, CF1-4000
    Cam Smith logo7C.Smith, RF0-4000
    Brendan Rodgers logo8B.Rodgers, 2B0-3000
    Victor Caratini logo8V.Caratini, PH0-1000
    Mauricio Dubon logo9M.Dubon, LF2-2111
    Rays Player Stats
    Projected
    PITCHERPCIPKER
    Taj Bradley logoRT.Bradley, P84672
    Garrett Cleavinger logoLG.Cleavinger, P10110
    Edwin Uceta logoRE.Uceta, P15122
    Pete Fairbanks logoRP.Fairbanks, P20120
    HITTERSH-ABRHRRBI
    Yandy Diaz logo1Y.Diaz, DH2-5213
    Josh Lowe logo2J.Lowe, RF2-4111
    Brandon Lowe logo3B.Lowe, 2B1-4111
    Jonathan Aranda logo4J.Aranda, 1B1-5101
    Jose Caballero logo5J.Caballero, SS1-3000
    Chandler Simpson logo6C.Simpson, LF1-4001
    Kameron Misner logo7K.Misner, CF0-2100
    Curtis Mead logo8C.Mead, 3B2-3211
    Ben Rortvedt logo9B.Rortvedt, C0-4000

    Astros vs. Rays Odds Comparison

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    Astros at Rays Team Totals

    MatchupOverUnder
    Astros
    15-23
    N/A
    N/A
    Rays
    25-12
    N/A
    N/A