Astros vs. Rays Odds & Betting Predictions - May 21, 2025

Astros at Rays

5:10 pm • FDSSUN

Houston Astros

25-24

4 - 8

Tampa Bay Rays

23-26

pitcher		team	era	w-l
T.Bradley			4.61	4-3
H.Brown			2.04	6-3

MatchupOpenSpreadTotalMoneyline
Astros 25-24	-1.5	-1.5+107	o8.5-112	-168
Rays 23-26	u9	+1.5-122	u8.5-110	+142

Wednesday 5:10 p.m.

May 21, 2025

George M. Steinbrenner FieldTampa

T.Bradley u17.5 Outs+120

Full writeup: https://www.actionnetwork.com/mlb/houston-astros-vs-tampa-bay-rays-prediction-pick-odds-wednesday-may-21-qs?utm_source=action_app&utm_medium=app&utm_campaign=article_share

HOU -1-130

HOU -148

1.48u

HOU -0.5 (F5)-105

1.05u

T.Bradley o1.5 BB-117

HOU -158 (F5)

H.Brown o6.5 Ks-106

1.06u

Took this on NoVig, but Action doesn't have them as a book to track yet.

I.Paredes o1.5 Hits + Runs + RBIs-120

0.83u

Under 0.5 (1st Inn)-120

1.2u

HOU -135

Rays stuck in a home rut – 3-13 in last 16 at George M. Steinbrenner Field. Taj Bradley shaky – 5 ER in 4 IP last start, 9.95 ERA in 3 career outings vs Astros. Bullpen collapse: 5.86 ERA last 3 games. Houston’s offense clicking – Altuve, Meyers heating up. Hunter Brown = lights out. 6-2, 1.43 ERA, 0.829 WHIP in ‘25. 2-0 vs Rays, 1.06 ERA career. 27.0 bullpen innings last 3 games, 1.00 ERA, 0.67 WHIP. Brown last 3 starts: 1.83 ERA, 0.813 WHIP. No signs of slowing. Rays can’t solve him. Offense won’t save them. Bradley has 5 HR allowed in 12.2 IP vs HOU. Rays scoring just 3.79 runs/game at home (24th in MLB). Astros had won 5 of 7 before Tuesday. Multiple analysts backing Houston. Dimers model leans Astros (55%). Too many signs to ignore.

TB +122

3.66u

H.Brown o6.5 Ks-132

0.25u

TB +123

0.62u

Bet to +108

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No props found

MLB Public Betting

Rays are 3-2 in their last 5 games.
Rays are 2-3 in their last 5 games against the spread
Rays are 10-8 in their road games against the spread
The totals have gone OVER in 1 of Rays' last 5 games
The totals have gone OVER in 12 of Rays' 31 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Rays	22-27	12-19	10-8	9-17	13-9
Astros	26-23	13-11	13-12	15-18	11-4

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Rays	19-28-2	12-17-2	7-11	9-15-2	10-12
Astros	20-27-2	10-14	10-13-2	17-16	2-11-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Rays	23-26	13-18	10-8	12-14	11-11
Astros	25-24	15-9	10-15	18-15	7-8

date	opponent	score	spread	over/under	moneyline
May 20th	HOU	W 3-2	-1.5 L	U 9	TB -135
May 19th	HOU	L 3-4	-1.5 L	U 9	HOU -144
May 18th	@MIA	L 1-5	-1.5 L	U 9	MIA -164
May 17th	@MIA	W 4-0	-1.5 W	U 8	TB -147
May 16th	@MIA	L 4-9	-1.5 L	O 8.5	MIA -126

Alex Faedo
P
Faedo is out with shoulder
Out
Shane McClanahan
P
McClanahan is out with triceps
Out
Jake Mangum
OF
Mangum is out with groin
Out
Richie Palacios
IF
Palacios is out with knee
Out
Ha-Seong Kim
IF
Kim is out with shoulder
Out
Jonny DeLuca
OF
DeLuca is out with shoulder
Out

Taylor Trammell
OF
Trammell is out with calf
Out
Cristian Javier
P
Javier is out with elbow
Out
Luis Garcia
P
Garcia is out with elbow
Out
Pedro Leon
OF
Leon is out with knee
Out
J.P. France
P
France is out with shoulder
Out
Spencer Arrighetti
P
Arrighetti is out with thumb
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RH.Brown, P	91	5	4	5
LB.Sousa, P	25	2	3	0
RF.Whitley, P	33	0.2	1	3
LS.Okert, P	6	0.1	0	0

HITTERS	H-AB	R	HR	RBI
1J.Pena, SS	0-3	1	0	0
2I.Paredes, 3B	2-4	2	2	3
3J.Altuve, DH	0-3	0	0	0
4Y.Diaz, C	1-4	0	0	0
5C.Walker, 1B	1-4	0	0	0
6J.Meyers, CF	1-4	0	0	0
7C.Smith, RF	0-4	0	0	0
8B.Rodgers, 2B	0-3	0	0	0
8V.Caratini, PH	0-1	0	0	0
9M.Dubon, LF	2-2	1	1	1

PITCHER	PC	IP	K	ER
RT.Bradley, P	84	6	7	2
LG.Cleavinger, P	10	1	1	0
RE.Uceta, P	15	1	2	2
RP.Fairbanks, P	20	1	2	0

HITTERS	H-AB	R	HR	RBI
1Y.Diaz, DH	2-5	2	1	3
2J.Lowe, RF	2-4	1	1	1
3B.Lowe, 2B	1-4	1	1	1
4J.Aranda, 1B	1-5	1	0	1
5J.Caballero, SS	1-3	0	0	0
6C.Simpson, LF	1-4	0	0	1
7K.Misner, CF	0-2	1	0	0
8C.Mead, 3B	2-3	2	1	1
9B.Rortvedt, C	0-4	0	0	0