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Duke vs. Notre Dame Odds & Betting Predictions - February 25, 2026

Duke at Notre Dame

12:00 am • ESPN

Duke Blue Devils

32-2
100
100 - 56

Notre Dame Fighting Irish

13-18
56

Duke at Notre Dame Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Duke
32-2
-14.5
-17-112
o142-115
-2000
Notre Dame
13-18
u139
+17-107
u142-115
+1050
location pinWednesday 12:00 a.m.
February 25, 2026
Purcell PavilionSouth Bend
Duke vs. Notre Dame Expert Picks
Allan Lem
Allan Lem
Last 30d: 108-88-0 (+3.5u)
Under 142.5-115
0.58u
Tailing @The_Oddsmaker
Sean Koerner
Sean Koerner
Last 30d: 42-39-0 (+2.7u)
Under 142.5-115
0.58u
Roger Goodell
Roger Goodell
Last 30d: 6-12-0 (-7.5u)
Under 66.5 (1H)-113
1u
Mike McNamara
Mike McNamara
Last 30d: 88-115-1 (-0.0u)
ND +18.5-120
0.4u
Duck
Duck
Last 30d: 68-69-0 (-1.5u)
ND +18.5-120
0.55u
Doug Ziefel
Doug Ziefel
Last 30d: 194-250-13 (-7.2u)
Over 138.5-115
0.5u
JMann
JMann
Last 30d: 34-47-0 (-8.4u)
DUKE -15.5-110
1.36u
Duke’s elite defense against a ND offense without their 2 leading scorers in Burton and Harlason.

Duke vs. Notre Dame Previews & Analysis

  • Duke vs Notre Dame: Fighting Irish to Struggle? article feature image

    Duke vs Notre Dame: Fighting Irish to Struggle?

    Jordan Mann•
    Feb 24, 2026 UTC
  • Fading This Situational Spot & More Tuesday NCAAB Bets article feature image

    Fading This Situational Spot & More Tuesday NCAAB Bets

    Action Network Staff•
    Feb 24, 2026 UTC
  • 66% O/U System Flags Next 2 Picks article feature image

    66% O/U System Flags Next 2 Picks

    Action AI•
    Feb 24, 2026 UTC
  • Duck: My 7 NCAAB Situational Spots to Target This Week article feature image

    Duck: My 7 NCAAB Situational Spots to Target This Week

    Joshua Nunn•
    Feb 24, 2026 UTC
See more NCAAB Coverage Right Arrow

Prop Odds Comparison

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No props found

Line Movement Tracker

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Duke vs. Notre Dame Public Betting Percentages

Away Logo

Duke

Public

Home Logo

Notre Dame

31%

Bets%

69%

Money%

NCAAB Public Betting Right Arrow

Betting Trends

  • Notre Dame are 1-4 in their last 5 games.
  • Notre Dame are 1-4 in their last 5 games against the spread
  • Notre Dame are 7-6 in their road games against the spread
  • The totals have gone OVER in 5 of Notre Dame' last 5 games
  • The totals have gone OVER in 13 of Notre Dame' 18 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Notre Dame		15-168-107-65-79-9
Duke		19-1511-128-315-131-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Notre Dame		21-1013-58-57-513-5
Duke		12-228-154-710-180-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Notre Dame		13-18N/AN/A9-33-15
Duke		32-2N/AN/A26-21-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Feb 21st@PITTL 68-73+3 LO 140PITT +130
Feb 14thGTW 89-74-5.5 WO 150.5ND -265
Feb 11th@SMUL 81-89+10.5 WO 154.5SMU +500
Feb 7thFSUL 79-82-1.5 LO 154.5FSU -120
Feb 5th@LOUL 65-76+18.5 WU 155.5LOU +1100

Notre Dame vs. Duke Injury Updates

Notre Dame Injuries

  • Markus Burton
    G

    Burton is out with foot

    Out

  • Tommy Ahneman
    C

    Ahneman is out with knee

    Out

Duke Injuries

    See more NCAAB Injuries Right Arrow
    Team Stats

    27-59 (46%)
    Field Goals
    19-52 (37%)
    34-38 (89%)
    Free Throws
    11-19 (58%)
    12-33 (36%)
    3P
    7-26 (27%)
    47
    Rebounds
    26
    20
    Assists
    9
    8
    Turnovers
    14
    11
    Steals
    1
    1
    Blocks
    0
    20
    Fouls
    21

    Duke vs. Notre Dame Odds Comparison

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    Duke at Notre Dame Team Totals

    MatchupOverUnder
    Duke
    32-2
    N/A
    N/A
    Notre Dame
    13-18
    N/A
    N/A