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Pacers vs. Cavaliers Odds & Betting Predictions - November 22, 2025

Pacers at Cavaliers

12:00 am • Amazon Prime Video

Indiana Pacers

15-47
109
109 - 120

Cleveland Cavaliers

39-24
120

Pacers at Cavaliers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Pacers
15-47
N/A
N/A
N/A
Cavaliers
39-24
N/A
N/A
N/A
location pinSaturday 12:00 a.m.
November 22, 2025
Rocket ArenaCleveland
Pacers vs. Cavaliers Expert Picks
YBK Picks.com
Last 30d: 6-3-0 (+6.4u)
Over 241.5-105
2u
Cam Is Money
Cam Is Money
Last 30d: 43-42-0 (-3.0u)
B.Mathurin o20.5 Pts-112
0.89u
Matt DiLeo
Matt DiLeo
Last 30d: 35-28-1 (+4.0u)
J.Tyson o12.5 Pts+Rebs-115
0.87u
Matt Moore
Matt Moore
Last 30d: 34-32-2 (-0.3u)
Under 241.5-110
0.1u
Kyle Murray
Kyle Murray
Last 30d: 69-96-2 (-7.1u)
B.Mathurin o20.5 Pts-115
1u
The Degenerates
The Degenerates
Last 30d: 84-72-6 (+4.6u)
P.Siakam o23.5 Pts-114
1u
Ryan Minion
Ryan Minion
Last 30d: 174-187-2 (+60.2u)
B.Mathurin o21.5 Pts-105
$1.05
B.Mathurin o29.5 Pts+Rebs+Ast-105
$1.00
Buckets Podcast
Buckets Podcast
Last 30d: 71-66-4 (+1.6u)
D.Mitchell u37.5 Pts+Rebs+Ast-114
0.5u
@ChicagoFlow ⭐️⭐️ https://myaction.app/v5zzJuSFtYb
Royals Props
Royals Props
Last 30d: 14-28-1 (-17.8u)
CLE o126.5-120
1.2u

Pacers vs. Cavaliers Previews & Analysis

  • NBA Player Props: 3 Picks for Friday article feature image

    NBA Player Props: 3 Picks for Friday

    Action Network Staff•
    Nov 21, 2025 UTC
  • Pacers vs Cavaliers: Moore's Over/Under Pick for Friday article feature image

    Pacers vs Cavaliers: Moore's Over/Under Pick for Friday

    Matt Moore•
    Nov 21, 2025 UTC
  • NBA Cup Best Bets: 6 Picks for Thursday article feature image

    NBA Cup Best Bets: 6 Picks for Thursday

    Action Network Staff•
    Nov 21, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Pacers vs. Cavaliers Public Betting Percentages

Away Logo

Pacers

Public

Home Logo

Cavaliers

50%

Bets%

50%

Money%

NBA Public Betting Right Arrow

Betting Trends

  • Cavaliers are 3-2 in their last 5 games.
  • Cavaliers are 3-2 in their last 5 games against the spread
  • Cavaliers are 14-17 in their road games against the spread
  • The totals have gone OVER in 2 of Cavaliers' last 5 games
  • The totals have gone OVER in 12 of Cavaliers' 32 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cavaliers		27-3613-1914-1718-319-5
Pacers		28-3417-1511-193-625-27

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cavaliers		30-3312-2018-1324-256-8
Pacers		28-3416-1612-182-726-26

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cavaliers		39-24N/AN/A32-177-7
Pacers		15-47N/AN/A3-612-40

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 20thHOUL 104-114+1.5 LU 233.5HOU +103
Nov 18thMILW 118-106-5.5 WU 234.5CLE -260
Nov 15thMEMW 108-100---
Nov 14thTORL 113-126-7.5 LO 238.5TOR -285
Nov 13th@MIAW 130-116+4.5 WO 239.5CLE +160

Cavaliers vs. Pacers Injury Updates

Cavaliers Injuries

  • Donovan Mitchell
    SG

    Donovan Mitchell (groin) out Wednesday.

    Out

  • Dean Wade
    PF

    Dean Wade (ankle) out Tuesday.

    Out

  • Max Strus
    SF

    Strus is out with foot

    Out

Pacers Injuries

  • Ivica Zubac
    C

    Zubac is out with ankle

    Out

  • Tyrese Haliburton
    PG

    Haliburton is out with achilles

    Out

  • Obi Toppin
    PF

    Obi Toppin (foot) probable Thursday.

    Probable

  • Johnny Furphy
    SG

    Furphy is out with knee

    Out

See more NBA Injuries Right Arrow
Player Stats
  • scoring
    Donovan Mitchell logo
    Donovan Mitchell
    32
    ppg
  • rebounding
    Evan Mobley logo
    Evan Mobley
    12
    rpg
  • assists
    player logo
    -
    7
    apg
  • shooting
    Jaylon Tyson logo
    Jaylon Tyson
    85.7
    fg%
Team Stats

37-88 (42%)
Field Goals
43-89 (48%)
24-26 (92%)
Free Throws
21-27 (78%)
11-37 (30%)
3P
13-35 (37%)
43
Rebounds
52
25
Assists
28
Turnovers
10
Steals
5
5
Blocks
8
22
Fouls
22

Pacers vs. Cavaliers Odds Comparison

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Pacers at Cavaliers Team Totals

MatchupOverUnder
Pacers
15-47
N/A
N/A
Cavaliers
39-24
N/A
N/A