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Pacers vs. Cavaliers Odds & Betting Predictions - November 22, 2025

Pacers at Cavaliers

12:00 am • Amazon Prime Video

Indiana Pacers

6-24
109
109 - 120

Cleveland Cavaliers

17-14
120

Pacers at Cavaliers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Pacers
6-24
N/A
N/A
N/A
Cavaliers
17-14
N/A
N/A
N/A
location pinSaturday 12:00 a.m.
November 22, 2025
Rocket ArenaCleveland
Pacers vs. Cavaliers Expert Picks
YBK Picks.com
Last 30d: 32-31-1 (-4.3u)
Over 241.5-105
2u
Cam Is Money
Cam Is Money
Last 30d: 109-91-3 (+9.4u)
B.Mathurin o20.5 Pts-112
0.89u
Matt DiLeo
Matt DiLeo
Last 30d: 47-32-0 (+5.8u)
J.Tyson o12.5 Pts+Rebs-115
0.87u
Matt Moore
Matt Moore
Last 30d: 64-69-0 (+3.9u)
Under 241.5-110
0.1u
Kyle Murray
Kyle Murray
Last 30d: 99-97-3 (+27.0u)
B.Mathurin o20.5 Pts-115
1u
The Degenerates
The Degenerates
Last 30d: 92-89-4 (-5.4u)
P.Siakam o23.5 Pts-114
1u
Buckets Podcast
Buckets Podcast
Last 30d: 73-80-3 (-5.5u)
D.Mitchell u37.5 Pts+Rebs+Ast-114
0.5u
@ChicagoFlow ⭐️⭐️ https://myaction.app/v5zzJuSFtYb
Royals Props
Royals Props
Last 30d: 39-39-1 (-4.1u)
CLE o126.5-120
1.2u

Pacers vs. Cavaliers Previews & Analysis

  • NBA Player Props: 3 Picks for Friday article feature image

    NBA Player Props: 3 Picks for Friday

    Action Network Staff•
    Nov 21, 2025 UTC
  • Pacers vs Cavaliers: Moore's Over/Under Pick for Friday article feature image

    Pacers vs Cavaliers: Moore's Over/Under Pick for Friday

    Matt Moore•
    Nov 21, 2025 UTC
  • NBA Cup Best Bets: 6 Picks for Thursday article feature image

    NBA Cup Best Bets: 6 Picks for Thursday

    Action Network Staff•
    Nov 21, 2025 UTC
  • Top NBA Plays & Props for Friday! | Buckets Podcast article feature image

    Top NBA Plays & Props for Friday! | Buckets Podcast

    Brandon Kravitz•
    Nov 21, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Pacers vs. Cavaliers Public Betting Percentages

Away Logo

Pacers

Public

Home Logo

Cavaliers

50%

Bets%

50%

Money%

NBA Public Betting Right Arrow

Betting Trends

  • Cavaliers are 2-3 in their last 5 games.
  • Cavaliers are 1-4 in their last 5 games against the spread
  • Cavaliers are 4-8 in their road games against the spread
  • The totals have gone OVER in 3 of Cavaliers' last 5 games
  • The totals have gone OVER in 7 of Cavaliers' 19 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cavaliers		9-225-144-88-201-2
Pacers		15-159-76-82-313-12

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cavaliers		15-167-128-414-141-2
Pacers		11-198-83-111-410-15

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cavaliers		17-14N/AN/A16-121-2
Pacers		6-24N/AN/A2-34-21

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 20thHOUL 104-114+1.5 LU 233.5HOU +103
Nov 18thMILW 118-106-5.5 WU 234.5CLE -260
Nov 15thMEMW 108-100---
Nov 14thTORL 113-126-7.5 LO 238.5TOR -285
Nov 13th@MIAW 130-116+4.5 WO 239.5CLE +160

Pacers vs. Cavaliers Injury Updates

Pacers Injuries

  • Tyrese Haliburton
    PG

    Haliburton is out with achilles

    Out

  • Aaron Nesmith
    SF

    Nesmith is out with knee

    Out

  • Obi Toppin
    PF

    Toppin is out with foot

    Out

  • Isaiah Jackson
    C

    Isaiah Jackson (concussion) out Tuesday.

    Out

  • Ben Sheppard
    SG

    Sheppard is out with calf

    Out

Cavaliers Injuries

  • Larry Nance
    PF

    Nance is out with calf

    Out

  • Max Strus
    SF

    Strus is out with foot

    Out

  • Sam Merrill
    SG

    Merrill is probable with hand

    Probable

See more NBA Injuries Right Arrow
Player Stats
  • scoring
    Donovan Mitchell logo
    Donovan Mitchell
    32
    ppg
  • rebounding
    Evan Mobley logo
    Evan Mobley
    12
    rpg
  • assists
    Darius Garland logo
    Darius Garland
    7
    apg
  • shooting
    Jaylon Tyson logo
    Jaylon Tyson
    85.7
    fg%
Team Stats

37-88 (42%)
Field Goals
43-89 (48%)
24-26 (92%)
Free Throws
21-27 (78%)
11-37 (30%)
3P
13-35 (37%)
43
Rebounds
52
25
Assists
28
Turnovers
10
Steals
5
5
Blocks
8
22
Fouls
22

Pacers vs. Cavaliers Odds Comparison

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Pacers at Cavaliers Team Totals

MatchupOverUnder
Pacers
6-24
N/A
N/A
Cavaliers
17-14
N/A
N/A