White Sox vs. Guardians Odds & Betting Predictions - April 10, 2025

White Sox at Guardians

5:10 pm • CLEG

Chicago White Sox

38-68

1 - 6

Cleveland Guardians

52-53

pitcher		team	era	w-l
G.Williams			3.51	6-4
J.Cannon			4.48	4-7

MatchupOpenSpreadTotalMoneyline
White Sox 38-68	+1.5	+1.5-105	o7.5+100	+205
Guardians 52-53	u7.5	-1.5-114	u7.5-122	-250

Thursday 5:10 p.m.

April 10, 2025

Progressive FieldCleveland

G.Williams o1.5 BB (Live)-155

0.65u

S.Kwan o1.5 Hits + Runs + RBIs-140

0.71u

G.Williams o5.5 Ks-126

0.79u

(CWS) Matt Thaiss o0.5 Batter Walks+145

1.02u

J.Cannon u3.5 Ks+105

Under 0.5 (1st Inn)-125

1.25u

Good to the -135 at Caesars

CLE -1.5-105

0.95u

White Sox bats ice cold – .198 AVG, .534 OPS in 7-game slide. Just 15 runs in that stretch. Injuries piling up – key hitters hurt. Cannon’s command shaky – 3 BB, 2 HBP in last start. Sox bullpen already has 3 blown saves. Guardians pitching locked in – just 1 ER last 2 games. Pen ranks top 3 in WHIP, opp BA. Gavin Williams got hit by CHW in 2024, but this lineup lacks power. Santana hot – batting .364 last 6, 2 HR. CLE lineup due for bounce after low-run wins. Cannon’s 56.5 GB% sets up for damage on gaps. CLE 6-1 vs CHW in last 7, 4-1 at home. Sox 0-5 on road, worst AL run support away. Guardians eyeing sweep behind hot arms, vets clicking.

G.Williams o6.5 Ks+154

0.52u

2.59% ev

MLB NRFI & YRFI Predictions: +550 for Today
Billy Ward•
Apr 10, 2025 UTC
White Sox vs. Guardians: Target Thursday's Total
Tony Sartori•
Apr 10, 2025 UTC

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No props found

MLB Public Betting

Guardians are 2-3 in their last 5 games.
Guardians are 2-3 in their last 5 games against the spread
Guardians are 30-25 in their road games against the spread
The totals have gone OVER in 1 of Guardians' last 5 games
The totals have gone OVER in 24 of Guardians' 50 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	54-51	24-26	30-25	21-20	33-30
White Sox	61-45	30-23	31-22	0-2	61-43

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	45-56-4	24-25-1	21-31-3	21-20	24-35-4
White Sox	47-55-4	28-22-3	19-33-1	0-2	47-53-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	52-53	25-25	27-28	26-15	26-37
White Sox	38-68	22-31	16-37	1-1	37-67

date	opponent	score	spread	over/under	moneyline
Apr 9th	CWS	W 3-2	-1.5 L	U 7.5	CLE -168
Apr 8th	CWS	W 1-0	-1.5 L	U 7.5	CLE -202
Apr 6th	@LAA	L 2-6	-1.5 L	U 9.5	LAA -111
Apr 6th	@LAA	L 4-10	-1.5 L	O 9	LAA -152
Apr 5th	@LAA	W 8-6	-1.5 W	O 8	CLE -118

Ben Lively
SP
Lively is out with elbow
Out
Shane Bieber
SP
Bieber is out with elbow
Out
John Means
SP
Means is out with elbow
Out

Ryan Noda
1B
Noda is out with quad
Out
Ky Bush
SP
Bush is out with elbow
Out
Drew Thorpe
SP
Thorpe is out with elbow
Out
Shane Smith
SP
Smith is out with ankle
Out

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PITCHER	PC	IP	K	ER
RJ.Cannon, P	102	5.1	6	6
RB.Wilson, P	19	1.2	0	0
RM.Clevinger, P	6	1	0	0

HITTERS	H-AB	R
1N.Maton, DH	1-3	1
2A.Vaughn, 1B	0-4	0
3M.Vargas, 3B	0-4	0
4M.Thaiss, C	1-3	0
5A.Slater, RF	1-4	0
6L.Sosa, 2B	2-4	0
7B.Baldwin, LF	0-4	0
8M.Taylor, CF	0-2	0
9J.Amaya, SS	0-3	0

PITCHER	PC	IP	K	ER
RG.Williams, P	94	5	7	1
RJ.Junis, P	20	2	1	0
LJ.Cantillo, P	33	2	4	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	4-5	2	1	4
2J.Ramirez, 3B	0-4	0	0	0
3C.Santana, DH	0-3	0	0	0
4K.Manzardo, 1B	1-4	1	1	2
5N.Jones, CF	1-4	0	0	0
6J.Noel, RF	1-4	1	0	0
7B.Naylor, C	1-3	1	0	0
8D.Schneemann, 2B	0-4	0	0	0
9B.Rocchio, SS	2-3	1	0	0