Guardians vs. Tigers Odds & Betting Predictions - September 16, 2025

Guardians at Tigers

10:40 pm • CLEG

Cleveland Guardians

1-2

7 - 5

Detroit Tigers

4-4

pitcher		team	era	w-l
C.Mize			3.87	14-6
J.Cantillo			3.21	5-3

MatchupOpenSpreadTotalMoneyline
Guardians 1-2	+1.5	+1.5-176	o8-114	+121
Tigers 4-4	u7	-1.5+145	u8-105	-145

Tuesday 10:40 p.m.

September 16, 2025

Comerica ParkDetroit

Under 8-105

1.05u

Tough matchup but I’m buying into the Joey Cantillo breakout. This has implications for both teams in the standings so I feel like they’ll treat this game with importance. Let’s back the pitching.

Under 8-103

1.25u

CLE +120

1.2u

CLE +130

0.65u

Bet to +125

Grants Dinger Tuesday HR Picks!!!
•
Sep 16, 2025 UTC
3 MLB Player Props for Tuesday
Alex Hinton•
Sep 16, 2025 UTC
Guardians vs Tigers: +160 SGP for AL Central Matchup
Dead President Picks•
Sep 16, 2025 UTC

See more MLB Coverage

No props found

MLB Public Betting

Tigers are 2-3 in their last 5 games.
Tigers are 1-4 in their last 5 games against the spread
Tigers are 32-49 in their road games against the spread
The totals have gone OVER in 0 of Tigers' last 5 games
The totals have gone OVER in 41 of Tigers' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Tigers	73-89	41-40	32-49	49-64	24-23
Guardians	86-76	39-42	47-34	33-36	51-38

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Tigers	83-72-7	41-35-5	42-37-2	58-49-6	24-22-1
Guardians	69-87-6	37-41-3	32-46-3	34-34-1	34-50-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Tigers	87-75	46-35	41-40	64-49	23-24
Guardians	88-74	45-36	43-38	44-25	43-46

date	opponent	score	spread	over/under	moneyline
Sep 14th	@MIA	W 2-0	-1.5 W	U 9	DET -135
Sep 13th	@MIA	L 4-6	-1.5 L	O 8.5	MIA -132
Sep 12th	@MIA	L 2-8	-1.5 L	O 7	MIA -199
Sep 11th	@NYY	L 3-9	+1.5 L	O 8.5	NYY +140
Sep 10th	@NYY	W 11-1	+1.5 W	O 8	DET +142

Reese Olson
SP
Olson is out with shoulder
Out
Ty Madden
SP
Madden is out with shoulder
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
LJ.Cantillo, P	91	5	3	1
RM.Festa, P	19	0.2	0	1
LE.Sabrowski, P	12	0.2	0	0
RH.Gaddis, P	16	0.2	0	0
LT.Herrin, P	16	1	3	0
RC.Smith, P	18	1	2	1
RJ.Junis, P	14	1	1	1

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	2-5	1	0	1
2D.Schneemann, CF	0-3	0	0	0
2A.Martinez, PH	1-2	1	0	1
2A.Martinez, CF	1-2	1	0	1
3J.Ramirez, 3B	2-5	2	0	1
4K.Manzardo, DH	3-5	0	0	0
5B.Naylor, C	1-5	0	0	1
6G.Arias, SS	2-5	1	1	2
7N.Jones, RF	1-2	1	0	0
7D.Fry, PH	0-1	0	0	0
7J.Noel, PR	0-2	0	0	0
7J.Noel, RF	0-2	0	0	0
8C.Kayfus, 1B	1-4	0	0	1
9B.Rocchio, 2B	0-4	1	0	0

PITCHER	PC	IP	K	ER
RC.Mize, P	87	5.1	8	3
LT.Holton, P	18	1.2	1	0
LB.Horn, P	20	0.2	1	0
RR.Montero, P	22	1.1	4	0
RW.Vest, P	22	1	1	3

HITTERS	H-AB	R	HR	RBI
1J.Jones, DH	0-2	0	0	0
1K.Carpenter, PH	1-1	1	1	1
1K.Carpenter, DH	1-1	1	1	1
2G.Torres, 2B	1-5	2	1	1
3W.Perez, RF	0-5	0	0	0
4S.Torkelson, 1B	4-5	1	1	2
5R.Greene, LF	1-4	1	0	0
6A.Ibanez, 3B	0-2	0	0	0
6C.Keith, PH	1-1	0	0	0
6C.Keith, 3B	1-1	0	0	0
6J.Rogers, PH	0-1	0	0	0
6T.Sweeney, SS	0-1	0	0	0
7D.Dingler, C	1-4	0	0	1
8P.Meadows, CF	0-3	0	0	0
9J.Baez, SS	0-3	0	0	0
9J.Baez, 3B	0-3	0	0	0
9Z.McKinstry, PH	0-1	0	0	0
9Z.McKinstry, 3B	0-1	0	0	0