Guardians vs. Red Sox Odds & Betting Predictions - September 3, 2025

Guardians at Red Sox

10:45 pm • NESN
8 - 1
Starting Pitchers
pitcherteameraw-l
Brennan Bernardino logoB.BernardinoBoston Red Sox logo3.144-3
Joey Cantillo logoJ.CantilloCleveland Guardians logo3.215-3

Guardians at Red Sox Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Guardians
1-2
+1.5
+1.5-164
o8.5-122
+123
Red Sox
1-2
u9
-1.5+137
u8.5-104
-150
location pinWednesday 10:45 p.m.
September 03, 2025
Fenway ParkBoston
Guardians vs. Red Sox Expert Picks
Wags Wins
Wags Wins
Last 30d: 192-193-1 (-10.0u)
CLE +130
1.3u
Allan Lem
Allan Lem
Last 30d: 171-124-3 (+14.9u)
Under 9+100
0.5u
Sean Zerillo
Sean Zerillo
Last 30d: 48-74-0 (-1.5u)
Over 9+100
0.5u
Bet to -115

Guardians vs. Red Sox Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Guardians vs. Red Sox Public Betting Percentages

Away Logo

Guardians

Public

16%

Bets%

84%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Red Sox
87-7543-3844-3753-5034-23
Guardians
86-7639-4247-3433-3651-38

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Red Sox
76-82-433-45-343-37-150-50-326-30-1
Guardians
69-87-637-41-332-46-334-34-134-50-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Red Sox
89-7348-3341-4061-4228-29
Guardians
88-7445-3643-3844-2543-46

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 2ndCLEW 11-7-1.5 WO 7.5BOS -255
Sep 1stCLEW 6-4-1.5 WO 8BOS -146
Aug 31stPITW 5-2-1.5 WU 8.5BOS -175
Aug 30thPITL 3-10-1.5 LO 9PIT -188
Aug 29thPITL 2-4+1.5 LU 8PIT -118

Guardians vs. Red Sox Injury Updates

Guardians Injuries

    Red Sox Injuries

    • Tanner Houck
      SP

      Houck is out with arm

      Out

    • Patrick Sandoval
      SP

      Sandoval is out with elbow

      Out

    • Kutter Crawford
      SP

      Crawford is out with knee

      Out

    • Jovani Moran
      RP

      Moran is out with arm

      Out

    Guardians vs. Red Sox Box Score
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Joey Cantillo logoLJ.Cantillo, P104671
    Jakob Junis logoRJ.Junis, P291.220
    Erik Sabrowski logoLE.Sabrowski, P191.110
    HITTERSH-ABRHRRBI
    Steven Kwan logo1S.Kwan, LF3-5201
    Angel Martinez logo2A.Martinez, CF1-4000
    Jose Ramirez logo3J.Ramirez, 3B0-3102
    Kyle Manzardo logo4K.Manzardo, DH0-4000
    Jhonkensy Noel logo5J.Noel, RF0-5000
    Bo Naylor logo6B.Naylor, C2-4200
    Gabriel Arias logo7G.Arias, SS1-3112
    George Valera logo7G.Valera, PH1-1000
    Daniel Schneemann logo7D.Schneemann, 2B0-0000
    CJ Kayfus logo8C.Kayfus, 1B2-3101
    Brayan Rocchio logo9B.Rocchio, 2B1-4100
    Brayan Rocchio logo9B.Rocchio, SS1-4100
    Red Sox Player Stats
    Projected
    PITCHERPCIPKER
    Brennan Bernardino logoLB.Bernardino, P170.201
    Jordan Hicks logoRJ.Hicks, P160.114
    Steven Matz logoLS.Matz, P14101
    Zack Kelly logoRZ.Kelly, P63440
    Dustin May logoRD.May, P53311
    HITTERSH-ABRHRRBI
    Nate Eaton logo1N.Eaton, 3B1-3000
    Nathaniel Lowe logo1N.Lowe, PH0-1000
    Nathaniel Lowe logo1N.Lowe, 1B0-1000
    Alex Bregman logo2A.Bregman, DH0-4000
    Trevor Story logo3T.Story, SS0-3000
    David Hamilton logo3D.Hamilton, PH0-1000
    David Hamilton logo3D.Hamilton, SS0-1000
    Romy Gonzalez logo4R.Gonzalez, 1B2-4000
    Romy Gonzalez logo4R.Gonzalez, 2B2-4000
    Rob Refsnyder logo5R.Refsnyder, RF1-3100
    Jarren Duran logo6J.Duran, LF1-3000
    Ceddanne Rafaela logo7C.Rafaela, CF0-4000
    Nick Sogard logo8N.Sogard, 2B1-4001
    Nick Sogard logo8N.Sogard, 3B1-4001
    Connor Wong logo9C.Wong, C1-3000
    Ali Sanchez logo9A.Sanchez, C0-1000

    Guardians vs. Red Sox Odds Comparison

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    Guardians at Red Sox Team Totals

    MatchupOverUnder
    Guardians
    1-2
    o3.5-138
    u3.5+107
    Red Sox
    1-2
    o4.5-106
    u4.5-124