Cardinals vs. Pirates Odds & Betting Predictions - April 29, 2026

Cardinals at Pirates

10:40 pm • SportsNet PT

St. Louis Cardinals

16-13

1 - 0

Pittsburgh Pirates

16-14

MatchupOpenSpreadTotalMoneyline
Cardinals 16-13	+1.5	+1.5-193	o8.5-110	+113
Pirates 16-14	u8.5	-1.5+164	u8.5-110	-131

Wednesday 10:40 p.m.

April 29, 2026

PNC ParkPittsburgh

STL +125 (Live)

B.Chandler o4.5 Ks-114

0.5u

B.Chandler o15.5 Outs+119

0.5u

PIT -125

0.63u

Bet to -133

STL +110

O.Cruz o1.5 Hits + Runs + RBIs-145

$1.45

O.Cruz To Hit 1+ Home Runs Yes+525

0.23u

#EV 9.71% Pinny +391 Circa +400

STL +125

Join Discord. All picks posted before 8am https://discord.gg/HjKxYKdSUy This is a live-dog series spot, not a clean pitching-trust bet. St. Louis has already won 4-2 and 11-7 in Pittsburgh, and Chandler enters with a 4.88 ERA. Pallante's 4.26 ERA is the risk, but plus money fits the current matchup.

J.Walker o1.5 Hits + Runs + RBIs-107

1.07u

B.Chandler o4.5 Ks-121

1.21u

Cardinals vs Pirates: Fade Inflated Run Expectations
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No props found

MLB Public Betting

Pirates are 2-3 in their last 5 games.
Pirates are 2-3 in their last 5 games against the spread
Pirates are 9-6 in their road games against the spread
The totals have gone OVER in 2 of Pirates' last 5 games
The totals have gone OVER in 9 of Pirates' 15 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Pirates	17-13	8-7	9-6	10-6	7-7
Cardinals	18-11	9-6	9-5	1-1	17-10

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Pirates	16-14	9-6	7-8	9-7	7-7
Cardinals	15-13-1	8-7	7-6-1	1-1	14-12-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Pirates	16-14	8-7	8-7	10-6	6-8
Cardinals	16-13	7-8	9-5	1-1	15-12

date	opponent	score	spread	over/under	moneyline
Apr 28th	STL	L 7-11	-1.5 L	O 8.5	STL -160
Apr 27th	STL	L 2-4	-1.5 L	U 8	STL -121
Apr 26th	@MIL	L 0-5	-1.5 L	U 7.5	MIL +101
Apr 25th	@MIL	W 6-3	+1.5 W	O 8	PIT +101
Apr 24th	@MIL	W 6-0	-1.5 W	U 7	PIT -111

Jared Jones
SP
Jones is out with elbow
Out

Lars Nootbaar
LF
Nootbaar is out with heel
Out
Hunter Dobbins
SP
Dobbins is out with knee
Out

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PITCHER		PC	IP	K	ER
RA.Pallante, P		44	3	0	0

HITTERS	H-AB	R	RBI
1J.Wetherholt, 2B	1-2	0	1
2I.Herrera, C	0-1	0	0
3A.Burleson, 1B	0-2	0	0
4J.Walker, RF	0-2	0	0
5N.Gorman, DH	0-1	0	0
6M.Winn, SS	0-1	0	0
7N.Church, LF	0-2	0	0
8R.Urias, 3B	0-1	1	0
9V.Scott, CF	0-1	0	0

PITCHER		PC	IP	K	ER
RB.Chandler, P		71	4	5	1

HITTERS	H-AB	R	HR	RBI
1O.Cruz, CF	0-2	0	0	0
2B.Lowe, 2B	1-2	0	0	0
3B.Reynolds, LF	0-1	0	0	0
4R.O'Hearn, RF	0-1	0	0	0
5M.Ozuna, DH	0-1	0	0	0
6N.Gonzales, 3B	0-1	0	0	0
7S.Horwitz, 1B	0-1	0	0	0
8K.Griffin, SS	0-1	0	0	0
9J.Bart, C	1-1	0	0	0