Cardinals vs. Pirates Odds & Betting Predictions - April 27, 2026

Cardinals at Pirates

10:40 pm • CARD
@
Starting Pitchers
pitcherteameraw-l
Mason Montgomery logoM.MontgomeryPittsburgh Pirates logo3.971-0
Dustin May logoD.MaySt. Louis Cardinals logo5.843-2

Cardinals at Pirates Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cardinals
14-13
+1.5
+1.5-183
o8-118
+115
Pirates
16-12
u8.5
-1.5+152
u8-103
-132
location pinMonday 10:40 p.m.
April 27, 2026
PNC ParkPittsburgh
thermometer image70°Fahrenheit
rain image0%Rain
wind image10Wind
Cardinals vs. Pirates Expert Picks
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 293-298-11 (+16.8u)
D.May o15.5 Outs+108
0.71u
#EV 6.17% Pinny -123 BO -120
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 89-121-8 (+13.1u)
B.Lowe o1.5 Total Bases+140
1u
@cowhitchurch ⭐️⭐️⭐️ https://myaction.app/pHsh0nYiG2b
Brian Bitler
Brian Bitler
Last 30d: 87-83-0 (+12.6u)
STL +120
3u
Cam Is Money
Cam Is Money
Last 30d: 121-115-2 (+12.2u)
R.O'Hearn o1.5 Hits + Runs + RBIs-120
1.2u
W/ @RoyalsProps
RoyalsProps
RoyalsProps
Last 30d: 66-57-7 (+4.4u)
R.O'Hearn o1.5 Hits + Runs + RBIs-118
1.18u
@CamIsMoney18
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 293-298-11 (+16.8u)
Over 4.5 (F5)+105
0.55u
#EV 2.3% Pinny -106 Circa -110 BM -111 FD -108 BO -110
Doug Ziefel
Doug Ziefel
Last 30d: 269-337-21 (-20.0u)
D.May o15.5 Outs+114
0.44u
Frank Ammirante
Frank Ammirante
Last 30d: 314-340-14 (+5.1u)
Under 8.5-118
1.18u
D.May u2.5 Earned Runs-128
1.28u
Under 0.5 (1st Inn)-125
1.25u
Cam Is Money
Cam Is Money
Last 30d: 121-115-2 (+12.2u)
PIT -123
1.23u
Doug Ziefel
Doug Ziefel
Last 30d: 269-337-21 (-20.0u)
Under 8.5-112
0.56u

Cardinals vs. Pirates Previews & Analysis

  • A Historically Profitable Cardinals-Pirates Pick article feature image

    A Historically Profitable Cardinals-Pirates Pick

    PJ Walsh
    Apr 27, 2026 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Cardinals vs. Pirates Public Betting Percentages

Away Logo

Cardinals

Public

23%

Bets%

77%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Pirates
17-118-59-610-47-7
Cardinals
16-119-67-51-115-10

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Pirates
15-138-57-88-67-7
Cardinals
14-12-18-76-5-11-113-11-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Pirates
16-128-58-710-46-8
Cardinals
14-137-87-51-113-12

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 26th@MILL 0-5-1.5 LU 7.5MIL +101
Apr 25th@MILW 6-3+1.5 WO 8PIT +101
Apr 24th@MILW 6-0-1.5 WU 7PIT -111
Apr 24th@TEXL 1-6+1.5 LU 7.5TEX +135
Apr 23rd@TEXW 8-4-1.5 WO 7.5PIT -119

Pirates vs. Cardinals Injury Updates

Pirates Injuries

  • Jared Jones
    SP

    Jones is out with elbow

    Out

Cardinals Injuries

  • Lars Nootbaar
    LF

    Nootbaar is out with heel

    Out

  • Hunter Dobbins
    SP

    Dobbins is out with knee

    Out

Cardinals vs. Pirates Starting Lineups
Cardinals Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Dustin May logoRD.May, P3-25.841.5407.30
HITTERSAVGOBPSLGHR
JJ Wetherholt logo1J.Wetherholt, 2B.238.363.4065
Ivan Herrera logo2I.Herrera, C.240.403.4174
Alec Burleson logo3A.Burleson, 1B.245.328.3923
Jordan Walker logo4J.Walker, RF.283.360.5668
Nolan Gorman logo5N.Gorman, DH.225.297.3483
Masyn Winn logo6M.Winn, SS.265.347.3861
Nathan Church logo7N.Church, LF.269.311.5075
Ramon Urias logo8R.Urias, 3B.180.288.3602
Victor Scott logo9V.Scott, CF.191.243.2060
Pirates Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Mason Montgomery logoLM.Montgomery, P1-03.971.50016.68
HITTERSAVGOBPSLGHR
Oneil Cruz logo1O.Cruz, CF.259.320.5188
Brandon Lowe logo2B.Lowe, 2B.247.340.5277
Bryan Reynolds logo3B.Reynolds, LF.242.387.3743
Marcell Ozuna logo4M.Ozuna, DH.169.237.2582
Ryan O'Hearn logo5R.O'Hearn, RF.315.404.4894
Nick Gonzales logo6N.Gonzales, 3B.303.347.3480
Spencer Horwitz logo7S.Horwitz, 1B.257.372.3712
Konnor Griffin logo8K.Griffin, SS.224.286.3161
Henry Davis logo9H.Davis, C.161.266.2140

Cardinals vs. Pirates Odds Comparison

Right Arrow

Could not load odds

Cardinals at Pirates Team Totals

MatchupOverUnder
Cardinals
14-13
N/A
N/A
Pirates
16-12
N/A
N/A