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Astros vs. Orioles Odds & Betting Predictions - August 22, 2025

Astros at Orioles

11:05 pm • MLB Network

Houston Astros

7-11
10
10 - 7

Baltimore Orioles

9-8
7
Starting Pitchers
pitcherteameraw-l
Cade Povich logoC.PovichBaltimore Orioles logo5.213-8
Lance McCullers logoL.McCullersHouston Astros logo6.512-5

Astros at Orioles Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
7-11
-1.5
-1.5+137
o9.5-108
-116
Orioles
9-8
u9
+1.5-164
u9.5-114
-104
location pinFriday 11:05 p.m.
August 22, 2025
Oriole Park at Camden YardsBaltimore
Astros vs. Orioles Expert Picks
VegasIsMyBitch
VegasIsMyBitch
Last 30d: 0-0-0 (+0.0u)
Under 9+101
0.5u
1.5u play overall
Under 9+101
1u
Matt Trollo
Matt Trollo
Last 30d: 28-42-3 (-10.4u)
BAL -110
0.55u
Both pitchers have horrid contact profiles, but Povich's SIERA is a run better - BAL pen estimators 3/4 run better L30 days.
Scott Rickenbach
Scott Rickenbach
Last 30d: 100-120-4 (-28.6u)
Over 9.5-111
0.9u
Player Prop Savant
Player Prop Savant
Last 30d: 94-77-3 (+2.8u)
HOU o4.5 Team Total-117
1.25u
Sean Paul
Sean Paul
Last 30d: 19-23-1 (-3.4u)
BAL -110
1u
Derek Carty
Derek Carty
Last 30d: 7-27-3 (-6.5u)
Samuel Basallo o0.5 Hitter BBs+280
1u
@PayoffPitchPodcast https://myaction.app/GzR2JxlP2Vb
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 79-117-8 (-6.8u)
Samuel Basallo o0.5 Hitter BBs+280
1u
@DerekCarty https://myaction.app/FsqgauOO2Vb

Astros vs. Orioles Previews & Analysis

  • Astros vs Orioles: Bounce Back Spot article feature image

    Astros vs Orioles: Bounce Back Spot

    Sean Paul•
    Aug 22, 2025 UTC
  • Friday's MLB Best Bets article feature image

    Friday's MLB Best Bets

    Action Network Staff•
    Aug 22, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Astros vs. Orioles Public Betting Percentages

Away Logo

Astros

Public

Home Logo

Orioles

60%

Bets%

40%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Orioles are 3-2 in their last 5 games.
  • Orioles are 3-2 in their last 5 games against the spread
  • Orioles are 2-4 in their road games against the spread
  • The totals have gone OVER in 3 of Orioles' last 5 games
  • The totals have gone OVER in 6 of Orioles' 11 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Orioles		7-105-62-46-71-3
Astros		7-115-32-83-74-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Orioles		9-86-53-36-73-1
Astros		12-5-16-26-3-16-45-1-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Orioles		9-86-53-38-51-3
Astros		7-116-21-94-63-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Aug 21stHOUL 2-7+1.5 LO 8.5HOU -120
Aug 19th@BOSW 4-3+1.5 WU 9.5BAL +125
Aug 18th@BOSW 6-3-1.5 WO 8BAL +105
Aug 17th@HOUW 12-0-1.5 WO 8.5BAL -101
Aug 16th@HOUL 4-5+1.5 WO 8.5HOU +118

Orioles vs. Astros Injury Updates

Orioles Injuries

  • Adley Rutschman
    C

    Adley Rutschman has been scratched Saturday.

    Out

  • Heston Kjerstad
    LF

    Kjerstad is out with hamstring

    Out

  • Jordan Westburg
    3B

    Westburg is out with elbow

    Out

  • Jackson Holliday
    2B

    Holliday is out with hand

    Out

Astros Injuries

  • Zach Dezenzo
    LF

    Dezenzo is out with elbow

    Out

See more MLB Injuries Right Arrow
Astros vs. Orioles Box Score
Astros Player Stats
Projected
PITCHERPCIPKER
Lance McCullers logoRL.McCullers, P87443
Shawn Dubin logoRS.Dubin, P281.202
Steven Okert logoLS.Okert, P30.110
Enyel De Los Santos logoRE.De Los Santos, P19121
Kaleb Ort logoRK.Ort, P160.201
Bryan Abreu logoRB.Abreu, P211.140
HITTERSH-ABRHRRBI
Jeremy Pena logo1J.Pena, SS2-5114
Carlos Correa logo2C.Correa, 3B1-4100
Jose Altuve logo3J.Altuve, DH2-5100
Christian Walker logo4C.Walker, 1B1-5113
Yainer Diaz logo5Y.Diaz, C1-4000
Ramon Urias logo6R.Urias, 2B2-5100
Mauricio Dubon logo7M.Dubon, LF0-3100
Cam Smith logo8C.Smith, RF0-3100
Jesus Sanchez logo8J.Sanchez, PH0-1100
Jesus Sanchez logo8J.Sanchez, RF0-1100
Chas McCormick logo9C.McCormick, CF0-1100
Victor Caratini logo9V.Caratini, PH1-1002
Jacob Melton logo9J.Melton, PR0-0100
Jacob Melton logo9J.Melton, CF0-0100
Orioles Player Stats
Projected
PITCHERPCIPKER
Cade Povich logoLC.Povich, P964.254
Yennier Cano logoRY.Cano, P120.111
Kade Strowd logoRK.Strowd, P12100
Bowman logoRM.Bowman, P161.112
Martin logoRC.Martin, P201.221
HITTERSH-ABRHRRBI
Jackson Holliday logo1J.Holliday, 2B1-3001
Jeremiah Jackson logo2J.Jackson, RF2-5003
Gunnar Henderson logo3G.Henderson, SS2-5000
Ryan Mountcastle logo4R.Mountcastle, DH1-4000
Colton Cowser logo5C.Cowser, CF1-5111
Coby Mayo logo6C.Mayo, 1B0-3100
Dylan Beavers logo7D.Beavers, LF1-3200
Luis Vazquez logo8L.Vazquez, 3B2-3100
Samuel Basallo logo8S.Basallo, PH0-2000
Samuel Basallo logo8S.Basallo, C0-2000
Alex Jackson logo9A.Jackson, C2-3101
Vimael Machin logo9V.Machin, 3B1-2111

Astros vs. Orioles Odds Comparison

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Astros at Orioles Team Totals

MatchupOverUnder
Astros
7-11
N/A
N/A
Orioles
9-8
N/A
N/A