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Napoli vs. Milan Odds & Betting Predictions - September 28, 2025

Napoli at Milan

6:45 pm

SSC Napoli

14-5-4
1
1 - 2

AC Milan

13-1-8
2

Napoli at Milan Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Napoli
14-5-4
-1.5
+0.5-110
o2.5+100
N/A
Milan
13-1-8
u2.5
-0.5-115
u2.5-129
N/A
location pinSunday 6:45 p.m.
September 28, 2025
Giuseppe MeazzaMilan

Line Movement Tracker

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Napoli vs. Milan Public Betting Percentages

Away Logo

Napoli

Public

Home Logo

Milan

50%

Bets%

50%

Money%

Serie A Public Betting Right Arrow

Betting Trends

  • Milan are 3-1 in their last 5 games.
  • Milan are 2-3 in their last 5 games against the spread
  • Milan are 9-2 in their road games against the spread
  • The totals have gone OVER in 3 of Milan' last 5 games
  • The totals have gone OVER in 6 of Milan' 11 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Milan		15-76-59-211-74-0
Napoli		2-52-10-42-30-2

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Milan		10-126-54-710-80-4
Napoli		2-51-21-32-30-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Milan		13-17-1-36-0-512-1-51-0-3
Napoli		2-32-0-10-3-12-1-20-2

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 20th@UDIW 3-0-1 WO 2.5ACM -155
Sep 14thBFCW 1-0-0.5 WU 2.5ACM -130
Aug 29th@LECW 2-0-1 WU 2.5ACM -175
Aug 23rdCREL 1-2-1.5 LO 2.5CRE -310
May 24thMONW 2-0-2 LU 3ACM -424

Milan vs. Napoli Injury Updates

Milan Injuries

  • Ruben Loftus-Cheek
    MID

    Heel Injury

    Out

  • Christian Pulisic
    F

    Knock

    Out

  • Luka Modric
    MID

    Modric is doubtful

    Doubtful

  • Fikayo Tomori
    DEF

    Knock

    Out

  • Pervis Estupinan
    DEF

    Hamstring

    Out

  • Rafael Leao
    F

    Ankle/Foot Injury

    Out Indefinitely

  • Strahinja Pavlovic
    DEF

    Knock

    Out Indefinitely

Napoli Injuries

  • Romelu Lukaku
    F

    Lukaku is out with thigh

    Out

  • Frank Anguissa
    MID

    Suspended

    Out

  • Matteo Politano
    F

    Politano is out with thigh

    Out

  • Stanislav Lobotka
    MID

    Ankle/Foot Injury

    Out Indefinitely

  • Vanja Milinkovic-Savic
    GK

    Milinkovic-Savic is out with thigh

    Out

  • Mathias Olivera
    DEF

    Calf Muscle Strain

    Out Indefinitely

  • Giovanni Di Lorenzo
    DEF

    Di Lorenzo is out with knee

    Out

  • Pasquale Mazzocchi
    DEF

    Mazzocchi is out with leg

    Out

  • Amir Rrahmani
    DEF

    Rrahmani is out with muscle

    Out

  • Eljif Elmas
    MID

    Elmas is injured

    Out Indefinitely

See more SERIEA Injuries Right Arrow
Team Stats

6
Fouls
5
19
Shots
6
7
Corners
1
0
Offsides
1
0
Red Cards
1
0
Yellow Cards
1
7
Shots On Goal
3
64%
Possession Time
36%

Goalkeeping

Napoli vs. Milan Odds Comparison

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Could not load odds

See more Serie A Odds Right Arrow

Napoli at Milan Team Totals

MatchupOverUnder
Napoli
14-5-4
N/A
N/A
Milan
13-1-8
N/A
N/A