Sassuolo vs. Inter Odds & Betting Predictions - September 21, 2025

Sassuolo at Inter

6:45 pm

Sassuolo

10-11-5

1

1 - 2

Inter

21-4-1

2

MatchupOpenSpreadTotalMoneyline
Sassuolo 10-11-5	+1.5	+1.5-115	o3.5+125	N/A
Inter 21-4-1	u2.5	-1.5-125	u3.5-163	N/A

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Sunday 6:45 p.m.

September 21, 2025

Giuseppe MeazzaMilan

Serie A Public Betting

Inter are 3-2 in their last 5 games.
Inter are 3-2 in their last 5 games against the spread
Inter are 2-1 in their road games against the spread
The totals have gone OVER in 2 of Inter' last 5 games
The totals have gone OVER in 1 of Inter' 4 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Inter	3-4	1-3	2-1	3-2	0-1
Sassuolo	14-12	5-8	9-4	4-6	10-6

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Inter	3-4	1-3	2-1	1-4	1-0
Sassuolo	13-13	7-6	6-7	6-4	7-9

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Inter	4-3	2-2	2-1	4-1	0-1
Sassuolo	10-11	5-6-2	5-5-3	4-3-3	6-8-2

date	opponent	score	spread	over/under	moneyline
Sep 13th	@JUV	L 3-4	-0.5 L	O 2.5	-
Aug 31st	UDI	L 1-2	-1.5 L	O 2.5	-
Aug 25th	TOR	W 5-0	-1.5 W	O 2.5	INT -275
May 23rd	@COM	W 2-0	-0.5 W	U 3.5	INT -135
May 18th	LAZ	W 2-2	-1 L	O 2.5	LAZ -147

Nemanja Matic
MID
Calf/Shin Injury
Out Indefinitely
Armand Lauriente
F
Back Injury
Out

Edoardo Pieragnolo
DEF
Pieragnolo is doubtful with muscle
Doubtful
Daniel Boloca
MID
Boloca is out with knee
Out

Henrikh Mkhitaryan
MID
Back Injury
Out Indefinitely
Yann Sommer
GK
Ankle Ligaments
Out Indefinitely

Alessandro Bastoni
DEF
Bastoni is suspended with yellow cards
Lautaro Martinez
F
Martinez is out with calf
Out

See more SERIEA Injuries

Sassuolo

Inter

8

Fouls

13

7

Shots

15

3

Corners

7

3

Offsides

2

0

Red Cards

0

1

Yellow Cards

2

5

Shots On Goal

5

40%

Possession Time

60%

Sassuolo

Goalkeeping

Inter

Could not load odds

See more Serie A Odds

MatchupOverUnder
Sassuolo 10-11-5	N/A	N/A
Inter 21-4-1	N/A	N/A