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Sassuolo vs. Inter Odds & Betting Predictions - September 21, 2025

Sassuolo at Inter

6:45 pm

Sassuolo

3-4-1
1
1 - 2

Inter

5-3
2

Sassuolo at Inter Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Sassuolo
3-4-1
+1.5
+1.5-115
o3.5+125
N/A
Inter
5-3
u2.5
-1.5-125
u3.5-163
N/A
location pinSunday 6:45 p.m.
September 21, 2025
Giuseppe MeazzaMilan

Line Movement Tracker

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Sassuolo vs. Inter Public Betting Percentages

Away Logo

Sassuolo

Public

Home Logo

Inter

50%

Bets%

50%

Money%

Serie A Public Betting Right Arrow

Betting Trends

  • Inter are 3-0 in their last 5 games.
  • Inter are 3-0 in their last 5 games against the spread
  • Inter are 2-0 in their road games against the spread
  • The totals have gone OVER in 1 of Inter' last 3 games
  • The totals have gone OVER in 0 of Inter' 1 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Inter		3-01-02-03-0N/A
Sassuolo		4-42-22-21-23-2

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Inter		1-20-11-11-2N/A
Sassuolo		2-61-31-32-10-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Inter		3-01-02-03-0N/A
Sassuolo		3-42-21-2-11-1-12-3

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 13th@JUVL 3-4-0.5 LO 2.5-
Aug 31stUDIL 1-2-1.5 LO 2.5-
Aug 25thTORW 5-0-1.5 WO 2.5INT -275
May 23rd@COMW 2-0-0.5 WU 3.5INT -135
May 18thLAZW 2-2-1 LO 2.5LAZ -147

Sassuolo vs. Inter Injury Updates

Sassuolo Injuries

  • Nemanja Matic
    MID

    Calf/Shin Injury

    Out Indefinitely

  • Armand Lauriente
    F

    Back Injury

    Out

  • Edoardo Pieragnolo
    DEF

    Pieragnolo is doubtful with soreness

    Doubtful

  • Daniel Boloca
    MID

    Boloca is out with soreness

    Out

  • Tarik Muharemovic
    DEF

    Muharemovic is out with soreness

    Out

  • Laurs Skjellerup
    F

    Skjellerup is out with muscle

    Out

Inter Injuries

  • Matteo Darmian
    DEF

    Darmian is out with muscle

    Out

  • Henrikh Mkhitaryan
    MID

    Back Injury

    Out Indefinitely

  • Yann Sommer
    GK

    Ankle Ligaments

    Out Indefinitely

  • Raffaele Di Gennaro
    GK

    Di Gennaro is out with hand

    Out

See more SERIEA Injuries Right Arrow
Team Stats

8
Fouls
13
7
Shots
15
3
Corners
7
3
Offsides
2
0
Red Cards
0
1
Yellow Cards
2
5
Shots On Goal
5
40%
Possession Time
60%

Goalkeeping

Sassuolo vs. Inter Odds Comparison

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See more Serie A Odds Right Arrow

Sassuolo at Inter Team Totals

MatchupOverUnder
Sassuolo
3-4-1
o0.5-140
u0.5+105
Inter
5-3
o2.5+107
u2.5-152