Sassuolo vs. Inter Odds & Betting Predictions - September 21, 2025

Sassuolo at Inter

6:45 pm

Sassuolo

8-10-5

1

1 - 2

Inter

18-4-1

2

MatchupOpenSpreadTotalMoneyline
Sassuolo 8-10-5	+1.5	+1.5-115	o3.5+125	N/A
Inter 18-4-1	u2.5	-1.5-125	u3.5-163	N/A

location pin

Sunday 6:45 p.m.

September 21, 2025

Giuseppe MeazzaMilan

Serie A Public Betting

Inter are 3-2 in their last 5 games.
Inter are 3-2 in their last 5 games against the spread
Inter are 2-1 in their road games against the spread
The totals have gone OVER in 2 of Inter' last 5 games
The totals have gone OVER in 1 of Inter' 4 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Inter	3-4	1-3	2-1	3-2	0-1
Sassuolo	12-11	4-7	8-4	3-6	9-5

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Inter	3-4	1-3	2-1	1-4	1-0
Sassuolo	10-13	5-6	5-7	5-4	5-9

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Inter	4-3	2-2	2-1	4-1	0-1
Sassuolo	8-10	4-5-2	4-5-3	3-3-3	5-7-2

date	opponent	score	spread	over/under	moneyline
Sep 13th	@JUV	L 3-4	-0.5 L	O 2.5	-
Aug 31st	UDI	L 1-2	-1.5 L	O 2.5	-
Aug 25th	TOR	W 5-0	-1.5 W	O 2.5	INT -275
May 23rd	@COM	W 2-0	-0.5 W	U 3.5	INT -135
May 18th	LAZ	W 2-2	-1 L	O 2.5	LAZ -147

Henrikh Mkhitaryan
MID
Back Injury
Out Indefinitely
Yann Sommer
GK
Ankle Ligaments
Out Indefinitely
Nicolo Barella
MID
Barella is out with muscle
Out

Nemanja Matic
MID
Calf/Shin Injury
Out Indefinitely
Armand Lauriente
F
Back Injury
Out

Edoardo Pieragnolo
DEF
Pieragnolo is doubtful with muscle
Doubtful
Daniel Boloca
MID
Boloca is doubtful with muscle
Doubtful

See more SERIEA Injuries

Sassuolo

Inter

8

Fouls

13

7

Shots

15

3

Corners

7

3

Offsides

2

0

Red Cards

0

1

Yellow Cards

2

5

Shots On Goal

5

40%

Possession Time

60%

Sassuolo

Goalkeeping

Inter

Could not load odds

See more Serie A Odds

MatchupOverUnder
Sassuolo 8-10-5	N/A	N/A
Inter 18-4-1	N/A	N/A