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Pisa vs. Napoli Odds & Betting Predictions - September 22, 2025

Pisa at Napoli

6:45 pm

Pisa

1-11-11
2
2 - 3

SSC Napoli

14-5-4
3

Pisa at Napoli Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Pisa
1-11-11
+1.5
+1.5-135
o2.5-107
N/A
Napoli
14-5-4
u2.5
-1.5-106
u2.5-123
N/A
location pinMonday 6:45 p.m.
September 22, 2025
Stadio Diego Armando MaradonaNaples

Line Movement Tracker

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Pisa vs. Napoli Public Betting Percentages

Away Logo

Pisa

Public

Home Logo

Napoli

50%

Bets%

50%

Money%

Serie A Public Betting Right Arrow

Betting Trends

  • Napoli are 2-3 in their last 5 games.
  • Napoli are 2-3 in their last 5 games against the spread
  • Napoli are 0-4 in their road games against the spread
  • The totals have gone OVER in 2 of Napoli' last 5 games
  • The totals have gone OVER in 1 of Napoli' 3 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Napoli		2-52-10-42-30-2
Pisa		12-114-88-31-211-9

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Napoli		2-51-21-32-30-2
Pisa		10-132-108-30-310-10

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Napoli		2-32-0-10-3-12-1-20-2
Pisa		1-111-7-40-4-71-1-10-10-10

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 13th@FIOW 3-1-O 2.5-
Aug 30thCAGW 1-0-1.5 LU 2.5NAP -247
Aug 23rd@SASW 2-0-1 WU 2.5NAP -155
May 23rdCAGW 2-0-1.5 WU 3.5NAP -500
May 18th@PARL 0-0-1.5 L-PAR -221

Napoli vs. Pisa Injury Updates

Napoli Injuries

  • Romelu Lukaku
    F

    Lukaku is out with thigh

    Out

  • Frank Anguissa
    MID

    Suspended

    Out

  • Matteo Politano
    F

    Politano is out with thigh

    Out

  • Stanislav Lobotka
    MID

    Ankle/Foot Injury

    Out Indefinitely

  • Vanja Milinkovic-Savic
    GK

    Milinkovic-Savic is out with thigh

    Out

  • Mathias Olivera
    DEF

    Calf Muscle Strain

    Out Indefinitely

  • Giovanni Di Lorenzo
    DEF

    Di Lorenzo is out with knee

    Out

  • Pasquale Mazzocchi
    DEF

    Mazzocchi is out with leg

    Out

  • Amir Rrahmani
    DEF

    Rrahmani is out with muscle

    Out

  • Eljif Elmas
    MID

    Elmas is injured

    Out Indefinitely

Pisa Injuries

  • Juan Cuadrado
    DEF

    Cuadrado is out with hamstring

    Out

  • Mateus Lusuardi
    DEF

    Lusuardi is doubtful with soreness

    Doubtful

  • Isak Vural
    MID

    Vural is out with knee

    Out

  • Adrian Semper
    GK

    Semper is out with knee

    Out

See more SERIEA Injuries Right Arrow
Team Stats

16
Fouls
9
11
Shots
14
3
Corners
5
1
Offsides
1
0
Red Cards
0
2
Yellow Cards
1
7
Shots On Goal
6
36%
Possession Time
64%

Goalkeeping

Pisa vs. Napoli Odds Comparison

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Could not load odds

See more Serie A Odds Right Arrow

Pisa at Napoli Team Totals

MatchupOverUnder
Pisa
1-11-11
N/A
N/A
Napoli
14-5-4
N/A
N/A